“…Patient: Female, 42-year-old Final Diagnosis: Biliary neuroendocrine carcinoma involving the common hepatic duct • common bile duct and cystic duct PT1N0M0G3R0 Symptoms: Itching of the hands, forearms and lower legs, followed by symptoms of obstructive jaundice Clinical Procedure: Cholecystectomy • ERCP • resection of a hepatobiliary mass Specialty: Gastroenterology and Hepatology • Oncology • Pathology • Surgery OBJECTIVE: Rare disease BACKGROUND: Neuroendocrine tumors (NETs) primarily originating from the extrahepatic biliary (EB) tree are a medical rarity, accounting for less than 100 recorded instances globally. …”
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“…We further constructed seven time-ordered gene co-expression networks (TO-GCNs) of PFG biosynthesis genes (including EpPAL2, EpC4H, EpCHS2, EpCHI2, EpF3H, EpFLS3, and EpPT8), and three flavonol biosynthesis routines were then predicted. …”
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“…Transient ischemic attack (TIA), homocysteine, education, hematocrit (HCT), diabetes, hemoglobin, red blood cells (RBC), hypertension, prothrombin time (PT) were selected by Boruta algorithm. Logistic regression (AUC = 0.8595) was the best model for predicting MCI in high-risk groups of stroke, followed by elastic network (ENET) (AUC = 0.8312), multilayer perceptron (MLP) (AUC = 0.7908), extreme gradient boosting (XGBoost) (AUC = 0.7691), and support vector machine (SVM) (AUC = 0.7527), random forest (RF) (AUC = 0.7451), K-nearest neighbors (KNN) (AUC = 0.7380), decision tree (DT) (AUC = 0.6972). …”
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“…Clinically significant cancer at RP was defined as any of the following: (1) ISUP grade group 1 with tumor volume ≥1.3 mL; (2) ISUP grade group ≥2; or (3) the presence of advanced stage (≥pT3). RESULTS: Of the 120 men, data of 52 men who met the selection criteria for hemiablation were compared with final RP findings. …”
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“…This work demonstrates a convenient scanning-probe-induced proton evolution within WO(3), driving a reversible insulator-to-metal transition (IMT) at nanoscale. Specifically, the Pt-coated scanning probe serves as an efficient hydrogen catalysis probe, leading to a hydrogen spillover across the nano junction between the probe and sample surface. …”
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“…Warfarin doses were titrated to achieve prothrombin time (PT) increase to the levels seen with therapeutic human doses. …”
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“…To overcome the limitation in the use of CDDP in the treatment of GBM patients, fourth generation platinum compounds are been synthesized, one of them is the Pt(IV)Ac-POA, a prodrug with a medium-chain fatty acid as axial ligand, which acts as a histone 3 deacetylase inhibitor. …”
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“…We explore the impact of different back metal contacts (BMCs), including Cu, Ag, Fe, C, Au, W, Pt, Se, Ni, and Pd combined with the TiO(2) electron transport layer (ETL) and CFTS hole transport layer (HTL), on the performance of the devices. …”
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“…We noticed that lower immunoreactivity of CPS1 in IHCC was associated with tumor progression (pT status) with statistical significance (p = 0.003). …”
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“…Labs indicated anemia, thrombocytopenia, elevated PT and aPTT, high-titer inhibitor on mixing studies, positive ANA and anti-dsDNA antibodies, along with a triple-positive antiphospholipid antibody panel. …”
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“…For control cohorts, we had CSF samples from cognitively healthy individuals (n = 33) and patients with diagnosed AD and no iNPH (n = 39). *-31pt RESULTS: Levels of all investigated biomarkers differed significantly between groups, with the exception of t-Tau levels between healthy individuals and iNPH patients with AD pathology. …”
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“…Ten variables were found to influence survival significantly and were included in the final model, with the most important being lymph node positivity, pT stage and achieving an R0 resection. Patient characteristics including ASA grade and age were also influential. …”
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“…The final histopathological diagnosis was typical carcinoid, pT2aN0M0 stage IB based on the presence of pleural invasion. …”
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“…Glass–ceramic nanocomposites (GCNs) of (10 − x) BaTiO(3) (BT)–xPbTiO(3) (PT)–60V(2)O(5)–30B(2)O(3) with x = 0, 2.5, 5, 7.5 and 10 mol% were formed during heat treatment of conventional melt quenching glasses. …”
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“…Hence, the use of a small amount of Ru in cathodes (~0.04 g(Ru) per kW) is a promising strategy to solve the dichotomy between the capital and operational expenditures of conventional alkaline electrolyzers for high-throughput operation, while facing the scarcity issues of Pt-group metals.…”
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“…In terms of degradation rate, the best anode material for electrochemical oxidation was Ti/RuO(2)–IrO(2), which had the highest degradation kinetic constant compared to Ti/Ta(2)O(5)–IrO(2) and Ti/Pt. Experiments showed the highest degradation rate of SAs at 8.3 pH. …”
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“…In addition, Fe-N,S-C-950 (Zn) shows an outstanding Zn–air battery performance with an open-circuit voltage (OCV) of 1.450 V and a peak power density of 121.9 mW cm(−2), which is higher than that of 20 wt% Pt/C. As a result, the as-prepared electrocatalyst in this work shows the development of the Zn-assisted strategy combined with the assembly of porphyrins as NNMEs for the enhancement of the ORR in both alkaline and acidic solutions.…”
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“…Pathological examination revealed mixed neuroendocrine and endometrioid adenocarcinoma, pT2N0M0, grade 3, and International Federation of Gynecology and Obstetrics stage 2. …”
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“…The assays tested on sthemO 301 were: PT, APTT (silica and kaolin activators), fibrinogen (Fib), thrombin time (TT), chromogenic and clotting protein C (PC) activity, and von Willebrand factor antigen (VWF:Ag) levels. …”
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“…RESULTS: CORE-OM (“Clinical Outcomes in Routine Evaluation-Outcome Measure”) showed improvement in all of four dimensions: subjective well-being (TW), problems/symptoms (PT), general function (TF) and risk (TR). Perception of clinical improving measured by CGI was 81,6%. …”
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