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  1. 21061
    “…Overexpression of SIK1 improved hyperglycaemia, hyperlipidaemia and fatty liver, reduced the expression of cAMP-response element binding protein (CREB)-regulated transcription co-activator 2 (CRTC2), phosphoenolpyruvate carboxykinase (PEPCK), glucose-6-phosphatase (G6Pase), pS577 SIK1, sterol regulatory element binding-protein-1c (SREBP-1c) and its target genes, including acetyl-CoA carboxylase (ACC) and fatty acid synthase (FAS), and increased the expression of SIK1, pT182 SIK1 and pS171 CRTC2 in diabetic rat livers with the suppression of gluconeogenesis and lipid deposition. …”
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    Adenovirus-mediated expression of SIK1 improves hepatic glucose and lipid metabolism in type 2 diabetes mellitus rats
  2. 21062
    “…To make this data available to the scientific community and public health authorities we developed CPLP-TB (available at http://cplp-tb.ff.ulisboa.pt), an online database coupled with web-based tools for exploratory data analysis. …”
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    Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries
  3. 21063
    “…Three of the four patients receiving curative surgery developed hematogenous recurrence within two years of surgery and only one patient with pT1aN0M0 achieved long-term survival. The median overall survival of all six patients was 19.6 (6.4–40.5) months. …”
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    Clinicopathological characteristics and survival of primary malignant melanoma of the esophagus
  4. 21064
    “…These component vaccines were termed acellular vaccines and contained one or more pertussis antigens, including pertussis toxin (PT), filamentous haemagglutinin (FHA), pertactin (PRN), and fimbrial proteins 2 (FIM2) and 3 (FIM3). …”
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    Pertussis Prevention: Reasons for Resurgence, and Differences in the Current Acellular Pertussis Vaccines
  5. 21065
    “…The remaining pathogenic variants were c.235delC, p.T8M, p.R32H, p.R143Q, p.R143W, c‐23+1G>A. The only nonpathogenic variant was polymorphism p.V27I. …”
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    Frequency of GJB2 mutations, GJB6‐D13S1830 and GJB6‐D13S1854 deletions among patients with non‐syndromic hearing loss from the central region of Iran
  6. 21066
    “…Both DAPC and pairwise population differentiation analysis (Ф(PT)) revealed that the genetic groups were closely associated with geographical locations of pathogen collection. …”
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    Genetic and phenotypic diversity of Fusarium oxysporum f. sp. niveum populations from watermelon in the southeastern United States
  7. 21067
    “…The multivariate analysis revealed that abdominal LN dissection, pT category, and pN category were statistically significant prognostic factors. …”
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    The optimal extent of lymph node dissection in gastroesophageal junctional cancer: retrospective case control study
  8. 21068
    “…Isometric tetanic (Po) and twitch (Pt) forces were significantly elevated in the plantaris and soleus muscles of the INS/EX rats (P < 0.05). …”
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    Insulin and exercise improved muscle function in rats with severe burns and hindlimb unloading
  9. 21069
    “…A total of three heterozygous missense ESR1 mutations, p.K303R (c.908A>G), p.T311M (c.932C>T) and p.Y537C (c.1610A>G), were identified in 3/207 (1.4%) cervical squamous cell carcinoma samples, which were absent in 27 adenosquamous carcinomas and 26 adenocarcinomas samples. …”
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    Estrogen receptor 1 mutations in 260 cervical cancer samples from Chinese patients
  10. 21070
    “…The inequality analysis was conducted employing decomposition analysis using ADePT software version 6. Logistic regression models were used to show the association between NCD risk factors and socioeconomic status using SPSS version 25. …”
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    Socioeconomic inequalities in non-communicable disease risk factors in Botswana: a cross-sectional study
  11. 21071
    “…Four distinct genotypes (designated D, PtEb IX, VIC_cat1 and VIC_dog1) of E. bieneusi were identified in 20 of the 514 faecal samples (3.9%). …”
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    Enterocytozoon bieneusi genotypes in cats and dogs in Victoria, Australia
  12. 21072
    “…The pathological assessment showed a pT3a N0, M0 tumour compatible with AS of the kidney. …”
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    Primary Angiosarcoma of the Kidney: Case Report and Comprehensive Literature Review
  13. 21073
    “…The following radiological measures of spinal alignment were measured at three time points, preoperatively, on the first day of standing postoperatively and at 2 years post-surgery: sagittal vertical axis (SVA), lumbar lordosis (LL), thoracic kyphosis (TK), pelvic tilt (PT), and PI-LL. RESULTS: Postoperative change in TK was correlated to preoperative TK and age. …”
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    Postoperative Change of Thoracic Kyphosis after Corrective Surgery for Adult Spinal Deformity
  14. 21074
    “…No significant differences in OS were observed between PORT and non-PORT groups for patients of different ages, sex, tumor sizes or pT stages, and histological types. Conclusions: The findings of this meta-analysis supported a role for PORT in patients with completely resected pIIIA-N2 NSCLC having multiple N2 metastases and favored withholding PORT to patients with single N2 station involvement. …”
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    The role of postoperative radiotherapy for completely resected pIIIA-N2 non-small cell lung cancer patients with different clinicopathological features: a systemic review and meta-analysis
  15. 21075
    “…Very low levels of reported PT in some countries, particularly in sub-Saharan Africa, suggests possible underreporting. …”
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    Reported patterns of pregnancy termination from Demographic and Health Surveys
  16. 21076
    “…INTERVENTIONS: In November 2016, the patient underwent a left hemicolectomy: the pathologic staging described a G2 adenocarcinoma pT3N1b. In May 2018, the Octreotide scan was negative. …”
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    Occurrence of second primary malignancies in patients with neuroendocrine tumors of the digestive tract: A case report
  17. 21077
    “…The parameters measured included trunk shift and Cobb angle, TK (thoracic kyphosis), TLK (thoraco-lumbar junction kyphosis), LL (lumbar lordosis), PI (pelvic incidence), SS (sacral slope), PT (pelvic tilt) and SVA (sagittal vertical axis). …”
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    Coronal and sagittal spinal alignment in lumbar disc herniation with scoliosis and trunk shift
  18. 21078
    “…Abbreviations: CSS: cancer-specific survival; LN(D): lymph node (dissection); MeSH: Medical Subject Headings; OS: overall survival; pT: pathological T stage; RCT: randomised controlled trial; RFS: recurrence-free survival; UTTCC: upper tract TCC…”
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    Lymph node dissection during nephroureterectomy: Establishing the existing evidence based on a review of the literature
  19. 21079
    “…We documented that age, acute infection, prothrombin time (PT), D-dimer, erythrocyte sedimentation rate, blood platelets, and anticoagulation were significantly associated with the occurrence of DVT (P < .05). …”
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    Risk Assessment in Chinese Hospitalized Patients Comparing the Padua and Caprini Scoring Algorithms
  20. 21080
    “…Immunohistochemical studies in a cohort of 152 paraffin‐embedded BC tissues displayed that upregulated expression of KIFC1 clearly correlated with pT status (P = .014) and recurrent status (P = .002). …”
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    Kinesin family member C1 accelerates bladder cancer cell proliferation and induces epithelial–mesenchymal transition via Akt/GSK3β signaling
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