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21081“…Varying concentrations (5–20 mg/mL) of the extract and fractions were tested in vitro on blood coagulation profile; clotting time (CT), prothrombin time (PT), and activated partial thromboplastin time (aPTT) of apparently healthy human volunteers, while phytochemical characterization of the Hexane fraction was done by gas chromatography-mass spectrometry (GC-MS). …”
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21082“…Data regarding biopsies, ultrasound, the computed tomography scan, adopted treatment strategy, treatment-emergent adverse effect, and a follow-up period of 312 patients with confirmed nonmuscle invasive bladder cancer (pTa, pTis, or pT1 stage; intermediate or high-risk cancer) were reviewed. …”
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21083por Çamtosun, Emine, Akıncı, Ayşehan, Demiral, Emine, Tekedereli, İbrahim, Sığırcı, Ahmet“…Molecular analysis detected a novel heterozygous mutation ‘NM_001024630.3p.T155P(c.463A>C)’ in the RUNX2 gene. At age seven years and two months old, because of her severe short stature, growth hormone (GH) treatment was started and she responded well to GH therapy with no adverse effects. …”
Publicado 2019
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21084“…We first predicted its secondary and tertiary structures on the basis of the Piriformospora indica Pi transporter (PiPT) and identified 28 amino acid residues potentially engaged in the activity of AtPHT1;1. …”
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21085por Ucar, Murat, Varol, Alkim T, Gülkesen, Kemal H, Caylan, Ahmet E, Kutlu, Ömer, Güntekin, Erol“…However, there was no statistically significant difference between the groups in terms of hemoglobin decrease, hospitalization and catheterization time, and intraoperative and postoperative complication rates. The rates of pT2 cancers’ positive surgical margins (PSMs) were 32.4% and 19.4%, respectively. …”
Publicado 2019
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21086por Schlomberg, Hendrik, Kröger, Julia, Savasci, Gökcen, Terban, Maxwell W., Bette, Sebastian, Moudrakovski, Igor, Duppel, Viola, Podjaski, Filip, Siegel, Renée, Senker, Jürgen, Dinnebier, Robert E., Ochsenfeld, Christian, Lotsch, Bettina V.“…K- and H-PHI adopt a uniquely long-lived photoreduced polaronic state in which light-induced electrons are stored for more than 6 h in the dark and released upon addition of a Pt cocatalyst. This work highlights the importance of structure–property relationships in carbon nitrides for the rational design of highly active hydrogen evolution photocatalysts.…”
Publicado 2019
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21087por Alduhaish, Osamah, Ubaidullah, Mohd, Al-Enizi, Abdullah M., Alhokbany, Norah, Alshehri, Saad M., Ahmed, Jahangeer“…Therefore, the mesoporous α-Fe(2)O(3)@g-C(3)N(4)-NCs bifunctional electro-catalysts can be considered as potential future low-cost alternatives for Pt/C catalysts, which are currently used in fuel cells.…”
Publicado 2019
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21088“…Furthermore, the results demonstrated that high expression of AGBL2 was associated with tumor histological grade, advanced pT/pN/pM and cancer stage according to the International Federation of Gynecology and Obstetrics (P<0.05). …”
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21089por Lebok, Patrick, von Hassel, Aurelia, Meiners, Jan, Hube-Magg, Claudia, Simon, Ronald, Höflmayer, Doris, Hinsch, Andrea, Dum, David, Fraune, Christoph, Göbel, Cosima, Möller, Katharina, Sauter, Guido, Jacobsen, Frank, Büscheck, Franziska, Prien, Kristina, Krech, Till, Krech, Rainer Horst, von der Assen, Albert, Wölber, Linn, Witzel, Isabell, Schmalfeldt, Barbara, Geist, Stefan, Paluchoswski, Peter, Wilke, Christian, Heilenkötter, Uwe, Terracciano, Luigi, Müller, Volkmar, Wilczak, Waldemar, Burandt, Eike Christian“…In the subset of NST cancers the prognostic effect of LPCAT1 expression was independent of pT, and BRE grade (p<0.0001 each). A comparison with molecular features showed that LPCAT1 was strongly associated with estrogen receptor negativity (p<0.0001), progesterone receptor negativity (p<0,0001), amplification of HER2 (p<0.0001) and MYC (p=0.0066), as well as deletions of PTEN (p<0.0001) and CDKNA2 (p=0.0151). …”
Publicado 2019
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21090“…In total, 946 (9.17%) SRC GC patients with pT1a-4bN0-3bM0 stage cancer were recruited. The optimal cut-off point for size was 49 mm. …”
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21091por Kashiwagi, Shinichiro, Asano, Yuka, Ishihara, Sae, Morisaki, Tamami, Takashima, Tsutomu, Tanaka, Sayaka, Amano, Ryosuke, Ohsawa, Masahiko, Hirakawa, Kosei, Ohira, Masaichi“…The final diagnosis, given the above findings, was left breast cancer (ACC) pT1N0M0 stage I triple-negative subtype.…”
Publicado 2019
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21092por Maeda-Katahira, Akiko, Nakamura, Natsuko, Hayashi, Takaaki, Katagiri, Satoshi, Shimizu, Satoko, Ohde, Hisao, Matsunaga, Tatsuo, Kaga, Kimitaka, Nakano, Tadashi, Kameya, Shuhei, Matsuura, Tomokazu, Fujinami, Kaoru, Iwata, Takeshi, Tsunoda, Kazushige“…Each DOA-plus patient harbored one of the monoallelic mutations in the OPA1 gene: c.1334G>A, p.R445H, c.1618A>C, p.T540P, and c.892A>C, p.S298R. Missense mutations accounted for 100% (4/4) of the DOA-plus families and only 11.5% (3/26) of the families with simple DOA. …”
Publicado 2019
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21093por Farhat, Waad, Azzaza, Mohamed, Mizouni, Abdelkader, Ammar, Houssem, ben Ltaifa, Mahdi, Lagha, Sami, Kahloul, Mohamed, Gupta, Rahul, Mabrouk, Mohamed Ben, Ali, Ali Ben“…The multivariate analysis identified four parameters independently associated with the risk of recurrence after curative surgery: a distal margin ≤ 2 cm (HR = 6.8, 95% CI 2.7–16.6, 6), extracapsular invasion of lymph node metastasis (HR = 4.4, 95% CI 1.3–14), tumor stenosis (HR = 4.3, 95% CI 1.2–15.2), and parietal invasion (pT3/T4 disease) (HR = 3, 95% CI 1.1–9.4). CONCLUSION: The determination of the prognostic factors affecting the recurrence of rectal adenocarcinoma after curative surgery allows us to define the high-risk patients for recurrence. …”
Publicado 2019
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21094“…Radiographic evaluation included the following elements: grade and percentage of listhesis (%L), lumbar lordosis (LL), lumbar-sacral angle (LSA), pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT) distinguishing between “balanced” and “unbalanced” patients. …”
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21095por Krajewska, Jolanta, Jarzab, Michal, Kukulska, Aleksandra, Czarniecka, Agnieszka, Roskosz, Jozef, Puch, Zbigniew, Wygoda, Zbigniew, Paliczka-Cieslik, Ewa, Kropinska, Aleksandra, Krol, Aleksandra, Handkiewicz-Junak, Daria, Jarzab, Barbara“…MATERIAL: The analyzed group involved 701 DTC patients staged pT(1b)-T(4)N(0)-N(1)M(0), who underwent total thyroidectomy and postoperative RAI therapy. …”
Publicado 2019
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21096por Li, Kun‐Kun, Mao, Cheng‐Yi, Zhang, Jing‐Ge, Ma, Qiang, Wang, Ying‐Jian, Liu, Xue‐Hai, Bao, Tao, Guo, Wei“…High expression of UTP14a in ESCC correlated significantly with tumor invasive depth (pT stage), which predicts poor disease‐free survival and disease‐specific survival, as indicated by the log‐rank test and Cox proportional hazards regression analysis. …”
Publicado 2019
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21097por Wei, Zhishun, Endo-Kimura, Maya, Wang, Kunlei, Colbeau-Justin, Christophe, Kowalska, Ewa“…The precursor (TNW) and the product (OAP) of US-HT reaction were modified with nanoparticles of noble metals (Au, Ag or Pt) by photodeposition. Samples were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), diffuse reflectance spectroscopy (DRS), scanning transmission electron microscopy (STEM) and time-resolved microwave conductivity (TRMC). …”
Publicado 2019
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21098por Rodrigue, Amélie, Margaillan, Guillaume, Torres Gomes, Thiago, Coulombe, Yan, Montalban, Gemma, da Costa e Silva Carvalho, Simone, Milano, Larissa, Ducy, Mandy, De-Gregoriis, Giuliana, Dellaire, Graham, Araújo da Silva Jr, Wilson, Monteiro, Alvaro N, Carvalho, Marcelo A, Simard, Jacques, Masson, Jean-Yves“…At the C-terminus, PALB2 variants p.L947F [c.2841G>T], p.L947S [c.2840T>C], and most strikingly p.T1030I [c.3089C>T] and p.W1140G [c.3418T>C], stood out with pronounced PARP inhibitor sensitivity and cytoplasmic accumulation in addition to marked defects in recruitment to DNA damage sites, interaction with BRCA2 and homologous recombination. …”
Publicado 2019
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21099por Mijnes, Jolein, Tiedemann, Janina, Eschenbruch, Julian, Gasthaus, Janina, Bringezu, Sarah, Bauerschlag, Dirk, Maass, Nicolai, Arnold, Norbert, Weimer, Jörg, Anzeneder, Tobias, Fasching, Peter A., Rübner, Matthias, Bruno, Benjamin, Heindrichs, Uwe, Freres, Jennifer, Schulz, Hanna, Hilgers, Ralf-Dieter, Ortiz-Brüchle, Nadina, von Serenyi, Sonja, Knüchel, Ruth, Kloten, Vera, Dahl, Edgar“…In the serum test cohort, a panel of SPAG6 and ITIH5 showed 63% sensitivity for DCIS and 51% sensitivity for early invasive tumor (pT1, pN0) detection at 80% specificity. The serum validation cohort revealed 50% sensitivity for DCIS detection on basis of NKX2-6 and ITIH5. …”
Publicado 2019
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21100por Ataka, Ryo, Ito, Takashi, Masui, Toshihiko, Seo, Satoru, Ishii, Takamichi, Ogiso, Satoshi, Yagi, Shintaro, Taura, Kojiro, Uemoto, Shinji“…He underwent flow diversion surgery and cholecystectomy, and the specimen showed adenocarcinoma foci, pT1, pStage IA. Five and a half years passed without any recurrence of bile duct cancer. …”
Publicado 2019
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