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  1. 21321
    “…There were 12 novel variants among all detected variants, including 3 missense variants (p.G393V, p.T482A, and p.R720P), 4 frameshift variants (p.R53Gfs(∗)49, p.N279Kfs(∗)17, p.I469Lfs(∗)4, p.I655Nfs(∗)12), 2 splicing variants (c.1637-2A > G, c.1951 + 1G > C), 2 stopgain variants (p.L278X, p.W652X) and 1 insertion variants (p.P315LinsT). …”
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    Genetic Analysis of 28 Chinese Families With Tyrosinase-Positive Oculocutaneous Albinism
  2. 21322
    “…Meta-analysis led to the identification of preterm community state types (PT-CSTs), which recur in healthy controls and NEC infants. …”
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    Unraveling the Microbiome of Necrotizing Enterocolitis: Insights in Novel Microbial and Metabolomic Biomarkers
  3. 21323
    “…RESULTS: The platelets (PLTs), fibrinogen (FIB), D-dimer (D-D), and prothrombin time (PT) in CTC-positive group were significantly higher than those in CTC-negative group. …”
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    Relationship between Hypercoagulable State and Circulating Tumor Cells in Peripheral Blood, Pathological Characteristics, and Prognosis of Lung Cancer Patients
  4. 21324
    “…Our mechanistic studies reveal that Mtb triggers mitochondrial permeability transition (mPT) and subsequently extensive macrophage necrosis, which requires activation of the NLRP3 inflammasome. …”
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    Gasdermin D mediates host cell death but not interleukin-1β secretion in Mycobacterium tuberculosis-infected macrophages
  5. 21325
    “…In the second experiment, the semen was diluted 4-times with PBS (−) containing 0.05 mM 5-ALA, and then sperm mitochondrial membrane depolarization and ATP levels after 1.5 h of incubation were analyzed with the MitoPT® JC-1 Assay and ATP Assay kits, respectively. …”
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    5-Aminolevulinic acid improves chicken sperm motility
  6. 21326
    “…Moreover, to gain insight into the factors that affect the current–potential profiles, cyclic voltammograms were recorded at both Pt and glassy carbon working electrodes and electrochemical impedance spectroscopy experiments performed for the first time on molecular carbonyl nanoclusters.…”
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    Atomically Precise Ni–Pd Alloy Carbonyl Nanoclusters: Synthesis, Total Structure, Electrochemistry, Spectroelectrochemistry, and Electrochemical Impedance Spectroscopy
  7. 21327
    “…This longitudinal study investigated the quantity and quality of SARS-CoV-2 antibody response in 846 specimens from 350 patients, comparing BNT162b2-vaccinated individuals (19 previously diagnosed with COVID-19, termed RecoVax; and 49 never diagnosed, termed NaiveVax) with 122 hospitalized unvaccinated (HospNoVax) and 160 outpatient unvaccinated (OutPtNoVax) COVID-19 patients. NaiveVax experienced delay in generating SARS-CoV-2 total antibodies (TAb) and surrogate neutralizing antibodies (SNAb) after the first vaccine dose (D1) but rapid increase in antibody levels after the second dose (D2). …”
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    Rapid, robust, and sustainable antibody responses to mRNA COVID-19 vaccine in convalescent COVID-19 individuals
  8. 21328
    “…The liver damage was more severe in the non-viral AH group with lower PT. There was more severe form, more transition to chronicity and more deaths in the non-viral AH group. …”
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    Spectrum of acute hepatitis and its clinical outcome in a central region in Tunisia
  9. 21329
    “…In this regard, Adaptive Neuro-Fuzzy Inference optimized by Gray Wolf Optimization (GWO) method was used to predict hydrogen adsorption energy (ΔG) obtained from density functional theory (DFT) for single transition-metal atoms including Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Zr, Nb, Mo, Tc, Ru, Rh, Pd, Ag, Cd, Hf, Ta, W, Re, Os, Ir, Pt, and Au embedded in N-doped carbon of different sizes. …”
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    On the evaluation of hydrogen evolution reaction performance of metal-nitrogen-doped carbon electrocatalysts using machine learning technique
  10. 21330
    “…The occurrence of major complications (Clavien–Dindo ≥ 3), operative time, pT3–T4, pathological node involvement (pN+) were prognostic factors associated with worse survival. …”
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    Extended Pleurectomy/Decortication for Malignant Pleural Mesothelioma: Humanitas’s Experience
  11. 21331
    “…Serum samples and clinical data of 557 men who underwent RP for PCa with pathological stage (pT) <3 at Martini Clinic (Hamburg, Germany) were used for analysis. …”
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    A novel serum biomarker quintet reveals added prognostic value when combined with standard clinical parameters in prostate cancer patients by predicting biochemical recurrence and adverse pathology
  12. 21332
    “…We investigate the shading coefficient of three kinds of metal films (gold–palladium alloy (Au/Pd), platinum (Pt), chromium (Cr)) under different coating times, and 3.5 min Au/Pd film is determined as the candidate of the nanofacula array fabrication for its lower thickness (about 23 nm) and higher shading coefficient (≥ 90%). …”
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    Preparation and characteristic analysis of nanofacula array
  13. 21333
    por Du, Lei, Zhang, Gaixia, Sun, Shuhui
    Publicado 2021
    “…One of the biggest challenges for PEM fuel cell technology is the high cost, attributed to the use of precious platinum group metals (PGM), e.g., Pt, particularly at cathodes where sluggish oxygen reduction reaction takes place. …”
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    Proton Exchange Membrane (PEM) Fuel Cells with Platinum Group Metal (PGM)-Free Cathode
  14. 21334
    “…Despite some controversial results and study limitations, PD-L1 expression by tumor cells may be related to clinic–pathologic features of adverse outcome, including advanced tumor stage (high pT, presence of lymph node, and distant metastases), positivity of surgical margins, high Grade Group, and castration resistance. …”
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    What Do We Have to Know about PD-L1 Expression in Prostate Cancer? A Systematic Literature Review. Part 2: Clinic–Pathologic Correlations
  15. 21335
    “…Additionally, in the multivariate analysis of the validation cohort, TSR predicted BR independent of other factors, i.e., pT, pN, and age (p = 0.04, HR 2.75, 95%CI 1.07–7.03). …”
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    Low Tumor-to-Stroma Ratio Reflects Protective Role of Stroma against Prostate Cancer Progression
  16. 21336
    “…Endotype 1 patients had low levels of inflammatory markers (ferritin, IL-6, CRP, LDH), low infectious markers (WBC, procalcitonin), and low degree of coagulopathy (PTT, PT), while endotype 4 had higher levels of those markers. …”
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    Identification of Endotypes of Hospitalized COVID-19 Patients
  17. 21337
    “…Selected area electron diffraction patterns indicated that the side or the end surface of the nanorods was attributable to the {110} or {111} facet, respectively. Deposition of Pt or PbO(2) on the nanorods revealed that the {110} or {111} facet acted as reductive or oxidative sites. …”
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    One-Pot Synthesis of Long Rutile TiO(2) Nanorods and Their Photocatalytic Activity for O(2) Evolution: Comparison with Near-Spherical Nanoparticles
  18. 21338
    “…They were used as drug delivery, photothermal (PT), contrast, therapeutic, radiosensitizing, and gene transfection agents. …”
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    Multifunctional Gold Nanoparticles for Improved Diagnostic and Therapeutic Applications: A Review
  19. 21339
    “…The viability assay combining the Pt treatment with qPCR thereby proved to be a promising method for the enumeration of viable MAP cells in foodstuffs, environmental, and clinical samples which could replace the time-consuming cultivation or laborious procedures required when using PMA.…”
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    A Novel Approach to the Viability Determination of Mycobacterium avium subsp. paratuberculosis Using Platinum Compounds in Combination With Quantitative PCR
  20. 21340
    “…Results: Higher PD-L1, TIMP2 and VIM mRNA levels were found in pT1 compared to pTa NMIBC. As evaluated by Kaplan–Meier and Univariate and Multivariate Cox analysis, enhancement of PD-L1, TWIST1 and TIMP2 expression reduces the recurrent free survival in NMIBC patients. …”
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    Correlation between High PD-L1 and EMT/Invasive Genes Expression and Reduced Recurrence-Free Survival in Blood-Circulating Tumor Cells from Patients with Non-Muscle-Invasive Bladder Cancer
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