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21721por Schmid, Sebastian C., Thümer, Leonore, Schuster, Tibor, Horn, Thomas, Kurtz, Florian, Slotta-Huspenina, Julia, Seebach, Judith, Straub, Michael, Maurer, Tobias, Autenrieth, Michael, Kübler, Hubert, Retz, Margitta, Protzer, Ulrike, Gschwend, Jürgen E., Hoffmann, Dieter“…RESULTS: We included 109 cases of bladder cancer with 41 superficial (pTa low grade) tumors, 56 invasive (pT1-T4) high grade tumors and 12 others (pTa high grade + pTis). …”
Publicado 2015
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21722“…Based on in silico study, from eight peptides, only three peptides of CSN1S2 protein, which carried by PePT1 to enter the small intestine. The fragments are PepT1-41-NMAIHPR-47; PepT1-182-KISQYYQK-189 and PepT1-214-TNAIPYVR-221. …”
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21723por Li, Ning, Xu, Miao, Li, Chao-Feng, Ou, Wei, Wang, Bao-Xiao, Zhang, Song-Liang, Xu, Peng-Fei, Yuan, Cheng, Huang, Qun-Ai, Wang, Si-Yu“…The association was not significantly modified by other risk factors for NSCLC, including smoking status, pathologic tumor-node-metastasis stage, pT category, pN category, and chemotherapy. CONCLUSIONS: There is an association between the ABO blood types and the survival of Chinese patients with resected NSCLC. …”
Publicado 2015
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21724por Bern, Murray M., Hazel, Diane, Deeran, Elizabeth, Richmond, John R., Ward, Daniel M., Spitz, Damon J., Mattingly, David A., Bono, James V., Berezin, Ronna H., Hou, Laura, Miley, Gerald B., Bierbaum, Benjamin E.“…Taking 1.0 mg warfarin for seven days preoperatively did not prolong the prothrombin time (PT). Two patients in Arm C had asymptomatic distal DVT. …”
Publicado 2015
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21725“…The complete EMT phenotype exhibited significant associations with young age (p=0.017), advanced pT (p<0.001) and pN (p<0.001) stages, higher histological grade (p<0.001), lymphovascular invasion (p<0.001), and triple negativity (p<0.001). …”
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21726por Lee, Jin Ho, Kang, Chang Moo, Bang, Seung Min, Choi, Jin Young, Seong, Jin Sil, Hwang, Ho Kyoung, Choi, Sung Hoon, Lee, Woo Jung“…Pathological tumor size (P < 0.001), pT stage (P = 0.001), pTNM stage (P = 0.002), combined vascular resection (P = 0.003), completeness of adjuvant therapy (P = 0.004) were found to be statistically significantly different between Groups 1 and 2. …”
Publicado 2015
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21727por Zhang, Gui-Ming, Zhu, Yao, Ma, Xiao-Cheng, Qin, Xiao-Jian, Wan, Fang-Ning, Dai, Bo, Sun, Li-Jiang, Ye, Ding-Wei“…As compared with patients in the low-NLR group, those in the high-NLR group had an increased risk of pT3–4 disease (odds ratio (OR), 1.883; 95% confidence interval (CI), 1.419–2.500; P < 0.001), and a 1.7-fold increased risk of lymph node involvement (OR, 1.685; 95% CI, 1.101–2.579; P = 0.016). …”
Publicado 2015
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21728“…RESULTS: Preoperative CEA levels were significantly associated with age, smoking history, pathologic stage including pT (pathologic tumor stge), pN (pathologic nodal stage) and overall pathological stage, tumor size and differentiation, pathologically positive total lymph node, N1 and N2 lymph node, N2 nodal station (0/1/2=1.83/2.94/7.21 ng/mL, p=0.019), and 5-year disease-free survival (0.591 in group with normal preoperative CEA levels vs. 0.40 in group with high preoperative CEA levels, p=0.001). …”
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21729por Xue, Yuhua, Ding, Yong, Niu, Jianbing, Xia, Zhenhai, Roy, Ajit, Chen, Hao, Qu, Jia, Wang, Zhong Lin, Dai, Liming“…Dye-sensitized solar cells, fabricated using the fiber as a counter electrode, showed a power conversion efficiency of 6.8% and outperformed their counterparts with an expensive Pt wire counter electrode by a factor of 2.5. These novel fiber-shaped graphene-RACNT energy conversion and storage devices are so flexible they can be woven into fabrics as power sources.…”
Publicado 2015
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21730por ZHAO, YUE, FENG, YUE, ZHANG, YUN-MEI, DING, XIAO-XUE, SONG, YU-ZHU, ZHANG, A-MEI, LIU, LI, ZHANG, HONG, DING, JIA-HUAN, XIA, XUE-SHAN“…As a result, 7 novel mutations (MYPN, p.E630K; TNNT2, p.G180A; MYH6, p.R1047C; TNNC1, p.D3V; DES, p.R386H; MYBPC3, p.C1124F; and MYL3, p.D126G), 3 variants of uncertain significance (RBM20, p.R1182H; MYH6, p.T1253M; and VCL, p.M209L), and 2 known mutations (MYH7, p.A26V and MYBPC3, p.R160W) were revealed to be associated with DCM. …”
Publicado 2015
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21731por Kessuwan, Kanonkporn, Kubota, Satoshi, Liu, Qi, Sano, Motohiko, Okamoto, Nobuaki, Sakamoto, Takashi, Yamashita, Hirofumi, Nakamura, Yoji, Ozaki, Akiyuki“…Genome-wide and chromosome-wide significances of growth-related quantitative trait loci (QTLs) (body weight (BW) and total length (TL)) were detected using non-parametric mapping, Kruskal-Wallis (K-W) analysis, simple interval mapping (IM) and a permutation test (PT). Two stages and two families of fish were used to confirm the QTL regions. …”
Publicado 2015
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21732por Fu, Qiang, Chang, Yuan, An, Huimin, Fu, Hangcheng, Zhu, Yu, Xu, Le, Zhang, Weijuan, Xu, Jiejie“…Multivariate analyses proved IL-6 and IL-6R as independent predictors after adjusting for demographic factors. Concordance index of pT-IL-6-IL-6R risk stratification was markedly higher compared with the stage, size, grade and necrosis prognostic model (0.724 vs 0.669, P=0.002) or UCLA Integrated Staging System (0.724 vs 0.642, P=0.007) in organ-confined ccRCC population during the first 5 years. …”
Publicado 2015
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21733por Delgado-Ratto, Christopher, Gamboa, Dionicia, Soto-Calle, Veronica E., Van den Eede, Peter, Torres, Eliana, Sánchez-Martínez, Luis, Contreras-Mancilla, Juan, Rosanas-Urgell, Anna, Rodriguez Ferrucci, Hugo, Llanos-Cuentas, Alejandro, Erhart, Annette, Van geertruyden, Jean-Pierre, D’Alessandro, Umberto“…The level of genetic diversity was similar in all areas (He = 0.66–0.76, p = 0.32) though genetic differentiation between areas was substantial (PHI(PT) = 0.17, p<0.0001). Principal coordinate analysis showed a marked differentiation between parasites from urban and rural areas. …”
Publicado 2016
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21734por Pina-Martins, Francisco, Vieira, Bruno M., Seabra, Sofia G., Batista, Dora, Paulo, Octávio S.“…In comparison with other SNP detection approaches, 4Pipe4 showed the best validation ratio, retrieving a smaller number of SNPs but with a considerably lower false positive rate than other methods. 4Pipe4’s source code is available at https://github.com/StuntsPT/4Pipe4.…”
Publicado 2016
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21735por Zhang, Shui-Shen, Xie, Xuan, Wen, Jing, Luo, Kong-Jia, Liu, Qian-wen, Yang, Hong, Hu, Yi, Fu, Jian-Hua“…Patients with downregulation of TRPV6 trended to have a higher rate of advanced pT stage in both mRNA cohort (P = 0.089) and protein cohort (P = 0.073), though not statistically significant. …”
Publicado 2016
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21736por Yanagi, Tadahiro, Mizuochi, Tatsuki, Takaki, Yugo, Eda, Keisuke, Mitsuyama, Keiichi, Ishimura, Masataka, Takada, Hidetoshi, Shouval, Dror S., Griffith, Alexandra E., Snapper, Scott B., Yamashita, Yushiro, Yamamoto, Ken“…We identified a novel mutation (c.537G > A, p.T179T) in exon 4 of the IL10RA gene causing unique splicing aberrations and resulting in lack of signaling through the interleukin-10 receptor. …”
Publicado 2016
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21737por Wu, Bo-Kai, Yuan, Rey-Yue, Lien, Huang-Wei, Hung, Chin-Chun, Hwang, Pung-Pung, Chen, Rita Pei-Yeh, Chang, Chun-Che, Liao, Yung-Feng, Huang, Chang-Jen“…Treatment with chemical compounds that exert anti-oxidative or neurotrophic effects also resulted in a similar protective effect and maintained human tau-GFP protein in a phosphorylated state, as detected by antibodies pT212 and AT8. CONCLUSIONS: The novel finding of this study is that we established an expression system expressing tau-GFP in zebrafish embryos were directly imaged and traced by time-lapse recording to evaluate the neurotoxicity induced by tau-GFP proteins. …”
Publicado 2016
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21738por Ninomiya, Itasu, Okamoto, Koichi, Tsukada, Tomoya, Saito, Hiroto, Fushida, Sachio, Ikeda, Hiroko, Ohta, Tetsuo“…The pathological diagnosis according to the Japanese classification of esophageal cancer was MtLt, 47 mm, 0-IIa + IIb, pT1a-MM, ie(+), INF-b, ly3, v0, pN4(4a), pIM1, M0, and pstage IVa. …”
Publicado 2015
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21739“…Genetic variation among individuals and within populations was found to be relatively low (A = 2.831; H(E) = 0.407), although there was marked differentiation among populations (PhiPT = 0.248). Bayesian, UPGMA and principal coordinates analyses detected three main genotypic clusters (K = 3), which were present at all seven populations. …”
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21740por Greifzu, Franziska, Parthier, Daniel, Goetze, Bianka, Schlüter, Oliver M., Löwel, Siegrid“…We have previously shown that OD-plasticity in adult mouse V1 is absent after a photothrombotic (PT) stroke lesion in the adjacent primary somatosensory cortex (S1). …”
Publicado 2016
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