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21761“…Cluster analysis with principal coordinate analysis (PCoA) and discriminant analysis of principal components (DAPC) identified fungicide-exposed isolates as a distinct group from non-exposed control isolates (PhiPT = 0.15, P = 0.001). Dendrograms based on neighbor-joining also supported allelic variation associated with fungicide-exposure. …”
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21762por Maphis, Nicole, Jiang, Shanya, Xu, Guixiang, Kokiko-Cochran, Olga N., Roy, Saktimayee M., Van Eldik, Linda J., Watterson, D. Martin, Lamb, Bruce T., Bhaskar, Kiran“…This also resulted in a significant reduction in AT180 (pT231) site tau phosphorylation and Sarkosyl-insoluble tau aggregates. …”
Publicado 2016
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21763por Ballard, Darren D, Choksi, Neel, Lin, Jingmei, Choi, Eun-Young, Elmunzer, B Joseph, Appelman, Henry, Rex, Douglas K, Fatima, Hala, Kessler, William, DeWitt, John M“…AIM: To investigate the outcomes and recurrences of pT1b esophageal adenocarcinoma (EAC) following endoscopic mucosal resection (EMR) and associated treatments. …”
Publicado 2016
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21764por Hwang, Sung Hwan, Kim, Hyun Il, Song, Jun Seong, Lee, Min Hong, Kwon, Sung Joon, Kim, Min Gyu“…There was a significant difference in overall survival between rN2 and rN3 groups in patients with pT4N3 (P=0.013). In contrast, the difference in metastatic lymph nodes was not significant in these patients (≥16 vs. <15; P=0.177). …”
Publicado 2016
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21765por Kang, Ho Won, Seo, Sung Pil, Kim, Won Tae, Kim, Yong-June, Yun, Seok Joong, Lee, Sang-Cheol, Choi, Young Deuk, Ha, Yun-Sok, Kim, Tae-Hwan, Kwon, Tae Gyun, Byun, Seok-Soo, Jeh, Seong Uk, Kim, Wun-Jae“…Locally advanced UTUC was defined as ≥ pT3 and/or pN1 disease. The influence of ASA-PS score on survival was evaluated by Kaplan-Meier analyses and a multivariate Cox regression model. …”
Publicado 2017
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21766por Chiong, Mary Anne D., Canson, Daffodil M., Abacan, Mary Ann R., Baluyot, Melissa Mae P., Cordero, Cynthia P., Silao, Catherine Lynn T.“…Six (6) novel mutations were observed (43%): p.C422F, p.P86Rfs*44, p.Q121*, p.L209Wfs*4, p.T409R, and c.1461_1462insN[710]. CONCLUSION: The age at diagnosis in this series was much delayed and majority of the patients presented with severe neurologic impairment. …”
Publicado 2017
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21767por Konishi, Hirotaka, Ichikawa, Daisuke, Itoh, Hiroshi, Fukuda, Kenichiro, Kakihara, Naoki, Takemura, Manabu, Okugawa, Kaori, Uchiyama, Kiyoshi, Nakata, Masashi, Nishi, Hiroshi, Kosuga, Toshiyuki, Komatsu, Shuhei, Okamoto, Kazuma, Otsuji, Eigo“…Univariate and multivariate analyses of the 113 patients who underwent R0 or R1 resection identified the factors of pT3/4 and limited lymphadenectomy as predictive of worse prognosis (HR = 4.68, P = 0.02 and HR =2.19, P = 0.05, respectively). …”
Publicado 2017
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21768por Sinacki, Marcin, Serkies, Krystyna, Dziadziuszko, Rafał, Narkowicz, Magdalena, Kamińska, Joanna, Lipniewicz, Joanna“…MATERIAL AND METHODS: Thirty consecutive pT1-3N0-1M0 breast cancer patients boosted between 2014 and 2015 with 10 Gy/10 pulses/hour PDR-BT following a computed tomography (CT) simulation with the multi-catheter implant were included. …”
Publicado 2017
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21769por Aravindan, Sheeja, Ramraj, Satishkumar, Kandasamy, Kathiresan, Thirugnanasambandan, Somasundaram S., Somasundaram, Dinesh Babu, Herman, Terence S., Aravindan, Natarajan“…HT-EA treatment resulted in translational repression of IR-induced CXCR4, COX2, β-catenin, MMP9, Ki-67, BAPX, PhPT-1, MEGF10, and GRB10 in residual PC. Muting CXCR4 or COX2 regulated the migration/invasion potential of IR-surviving cells, while forced expression of CXCR4 or COX2 significantly increased migration/invasion capabilities of PC cells. …”
Publicado 2016
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21770por Maeda, Yuko, Sato, Noriko, Naka-Mieno, Makiko, Mori, Seijiro, Arai, Tomio, Tanaka, Masashi, Muramatsu, Masaaki, Sawabe, Motoji“…The strongest associations were found with rs3750092 (p.E321G, OR: 0.36, 95% CI: 0.24–0.56, P = 6.09 × 10(−6)), a variant in the WAS/WASL interacting protein family 3 (WIPF3), and with rs1051338 (p.T16P, OR: 2.50, 95% CI: 1.70–3.66, P = 2.79 × 10(−6)) and rs2246942 (intronic, OR: 2.32, 95% CI: 1.58–3.41, P = 1.61 × 10(−5)), variants in the lysosomal acid lipase A (LIPA). …”
Publicado 2016
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21771“…Inclusion criteria included participation in or acceptance to the residency program, practice as a PT between 3 and 25 years, and 50% of workday being involved in direct patient care. …”
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21772por van Kessel, Kim E. M., van de Werken, Harmen J. G., Lurkin, Irene, Ziel – van der Made, Angelique C. J., Zwarthoff, Ellen C., Boormans, Joost L.“…Node-negative patients had a significantly lower tumor grade at TURBT (p = 0.03), a lower pT stage (p<0.01) and less frequent lymphovascular invasion (13% versus 38%, p<0.01) at radical cystectomy than node-positive patients. …”
Publicado 2017
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21773por Jernström, Sandra, Hongisto, Vesa, Leivonen, Suvi-Katri, Due, Eldri Undlien, Tadele, Dagim Shiferaw, Edgren, Henrik, Kallioniemi, Olli, Perälä, Merja, Mælandsmo, Gunhild Mari, Sahlberg, Kristine Kleivi“…Interestingly, two cell lines insensitive to trastuzumab (KPL4 and SUM190PT) showed sensitivity to an Akt1/2 kinase inhibitor. …”
Publicado 2017
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21774por Taga, Mariko, Minett, Thais, Classey, John, Matthews, Fiona E., Brayne, Carol, Ince, Paul G., Nicoll, James AR, Hugon, Jacques, Boche, Delphine“…Neocortex from 299 participants from the MRC Cognitive Function and Ageing Studies was analysed by immunohistochemistry for the expression of the phosphorylated (active) form of IKKβ [pSer(176/180)], IRS1 [pS(312)], JNK [pThr(183)/Tyr(185)] and PKR [pT(451)]. The data were analyzed to investigate whether the proteins were expressed together and in relation with metabolic disorders, dementia, Alzheimer's pathology and APOE genotype. …”
Publicado 2016
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21775por Heumann, Asmus, Kaya, Özge, Burdelski, Christoph, Hube-Magg, Claudia, Kluth, Martina, Lang, Dagmar S., Simon, Ronald, Beyer, Burkhard, Thederan, Imke, Sauter, Guido, Izbicki, Jakob R., Luebke, Andreas M., Hinsch, Andrea, Jacobsen, Frank, Wittmer, Corinna, Büscheck, Franziska, Höflmayer, Doris, Minner, Sarah, Tsourlakis, Maria Christina, Schlomm, Thorsten, Wilczak, Waldemar“…Similarly, significant associations with pT stage and Gleason grade (p < 0.0001 each) were driven by the ERG negative subset. …”
Publicado 2017
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21776“…Further studies are indicated to better understand the individual components of this multimodal treatment program. Pacik PT, Geletta S. Vaginismus Treatment: Clinical Trials Follow Up 241 Patients. …”
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21777“…Additionally, the expression of TPD52 was detected under the same condition and was shown to be positively correlated withtumor status (pathological assessment of the primary tumor (pT, P = 0.035), distant metastasis (pM, P = 0.001)) and CRC clinicopathology(P = 0.024). …”
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21778por Amirpour Haredasht, Sara, Polson, Dale, Main, Rodger, Lee, Kyuyoung, Holtkamp, Derald, Martínez-López, Beatriz“…We estimated five PD models with different weights namely: (i) geographical distance weight which contains the inverse distance between each pair of farms in kilometers, (ii) pig trade weight (PT (ji)) which contains the absolute number of pig movements between each pair of farms, (iii) the product between the distance weight and the standardized relative pig trade weight, (iv) the product between the standardized distance weight and the standardized relative pig trade weight, and (v) the product of the distance weight and the pig trade weight. …”
Publicado 2017
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21779por Chen, Meiqing, Wu, Pingxiao, Chen, Liya, Yang, Shanshan, Yu, Langfeng, Ding, Yuefei, Zhu, Nengwu, Shi, Zhenqing, Liu, Zehua“…The ORR activity performance of Fe-Mt-SS-C, including the value of onset potential (0.03 V) and E(1/2) (−0.09 V), was better than that of commercial 20 wt% Pt/C (−0.02 V and −0.18 V, respectively). Moreover, the Fe-Mt-SS-C possessed excellent durability and outstanding immunity toward methanol crossover effects. …”
Publicado 2017
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21780por Xiao, Yihong, Zhang, Chufan, Zhang, Xu, Cai, Guohui, Zheng, Yong, Zheng, Ying, Zhong, Fulan, Jiang, Lilong“…In this work, perovskite-phase Na(0.5)Bi(0.5)TiO(3) (NBT) oxygen conductor was chosen as the solid electrolyte to fabricate a novel highly sensitive NO(2) sensor with CuO as the sensing electrode and Pt as reference electrode. Na dopped Na(0.5)Bi(0.5)TiO(3) greatly improved the sensing performance of this sensor. …”
Publicado 2017
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