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  1. 21881
    “…Multivariate analysis showed that age < 65 years and pT2-3 stage were independent favorable prognostic factors for prolonged overall survival in patients with pathological stage IIIA disease. …”
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    Prognostic significance of 14v-lymph node dissection to D2 dissection for lower-third gastric cancer
  2. 21882
    “…Silencing OMA1 in vitro in patient-derived metastatic breast cancer cells isolated from the metastatic pleural effusion and atypical ductal hyperplasia mammary tumor specimens (21MT-1 and 21PT) enhances the formation of filopodia, increases cell proliferation (Ki67 expression), and induces epithelial-mesenchymal transition (EMT). …”
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    Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells
  3. 21883
    “…For TAMs subsets, high density of CD68+ TAMs in either intratumor (IT) (pooled HR = 1.417; 95% CI = 1.092–1.839; P = 0.009) or peritumor (PT) (pooled HR = 1.393; 95% CI = 1.022–1.899; P = 0.036) was associated with a poor OS. …”
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    Clinicopathologic and prognostic significance of tumor-associated macrophages in patients with hepatocellular carcinoma: A meta-analysis
  4. 21884
    “…As expected for a cofactor synthesis pathway, protein profiles failed to detect enzymes involved in NAD synthesis or utilization, except for nicotinic acid phosphoribosyltransferase (NaPT) and nicotinamidase (NIC), which suggested that most NAD metabolic enzymes were poorly represented quantitatively. …”
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    Regulation of Pyridine Nucleotide Metabolism During Tomato Fruit Development Through Transcript and Protein Profiling
  5. 21885
    “…Histopathology revealed a squamotransitional cervical cancer as the primary tumor with a tumor stage of pT3b, pN1 (1/2), V0, RX, G2, corresponding to International Federation of Gynecology and Obstetrics stage IIIB. …”
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    Papillary squamotransitional cell carcinoma of the uterine cervix: a case report and review of the literature
  6. 21886
    “…PATIENT CONCERNS: A 70-year-old man with squamous cell carcinoma of the middle third of the esophagus (initial staging, pT2N0M0; stage IIB; in January 2017) underwent Video-assisted esophagectomy and reconstruction with a gastric conduit via a substernal route. …”
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    Bronchoscopic cryosurgery for metastatic tumor causing central airway obstruction: A case report
  7. 21887
    “…Previously, we and others report that cyclin E/cyclin-dependent kinase 2 (CDK2) phosphorylates enhancer of zeste homolog 2 (EZH2) at T416 (pT416-EZH2). Here, we show that transgenic expression of phospho-mimicking EZH2 mutant EZH2(T416D) in mammary glands leads to tumors with TNBC phenotype. …”
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    CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer
  8. 21888
    “…Baseline investigations incorporated hemogram, liver biochemical parameters, coagulation parameters (PT/INR), serum creatinine, serum electrolytes and blood gas analysis, to calculate the CTP score, MELD, MELD-Na, MESO, iMELD, Updated MELD, UKELD, SOFA and APACHE II. …”
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    Scoring Systems that Predict Mortality at Admission in End-stage Liver Disease
  9. 21889
    “…Considering the 17 preoperatively potent patients who underwent bi- or unilateral nerve-sparing surgery, 41% reported their first sexual intercourse within 1 year after rsRARP. 84% of patients had ≥pT3a disease and 42% positive surgical margins. …”
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    Retzius-sparing robot-assisted laparoscopic radical prostatectomy: functional and early oncologic results in aggressive and locally advanced prostate cancer
  10. 21890
    “…Administration of a HIF-2α antagonist (PT2385) restored YTHDF2-programed epigenetic machinery and repressed liver cancer. …”
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    YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma
  11. 21891
    “…The BOLD co-activation of the L-ITG (ant) with bilateral frontal pole (FP) and paracingulate gyrus was positively associated with IRI-perspective taking (PT) (r = 0.38, p = 0.007), SNQ total (r = 0.37, p = 0.009), and TASIT-EET (r = 0.47, p < 0.001). …”
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    Association Between Social Cognition Changes and Resting State Functional Connectivity in Frontotemporal Dementia, Alzheimer’s Disease, Parkinson’s Disease, and Healthy Controls
  12. 21892
    “…Three variants, p.G313R, p.T418M, and p.L406P, in the WIPI1 gene were identified from the independent replication cohort consisting of 502 cases. …”
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    Whole-Exome Sequencing Identifies Damaging de novo Variants in Anencephalic Cases
  13. 21893
    “…Overall, 63% of the esophagi were T0N0: most residual lesions were T1a metachronous lesions, and four (13%) patients had advanced pT status (n = 3) or lymph node metastases (n = 2). …”
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    Outcomes of esophagectomy after noncurative endoscopic resection of early esophageal cancer
  14. 21894
    “…Results: Tumor invasion (pT) was significantly correlated with intratumoral (p = 0.011) and peritumoral (p = 0.016) CD8+ CTLs density in the tumor microenvironment. …”
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    Intratumoral Cytotoxic T-Lymphocyte Density and PD-L1 Expression Are Prognostic Biomarkers for Patients with Colorectal Cancer
  15. 21895
    “…RESULTS: Results from the DNA sequencing revealed five potential causative mutations: c.154 T > C(p.F52 L) in GJA8 of Family 1, c.1152_1153insG(p.S385Efs*83) in GJA3 of Family 2, c.1804 G > C(p.G602R) in BFSP1 of Family 3, c.1532C > T(p.T511 M) in EPHA2 of Family 4 and c.356G > A(p.R119H) in HSF4 of Family 5. …”
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    Novel mutations identified in Chinese families with autosomal dominant congenital cataracts by targeted next-generation sequencing
  16. 21896
    “…With a median follow–up of 64 months (range: 56–71), no local relapse occurred while 1 pt. developed an axillary relapse (2.1%). No Grade 3 or higher late toxicity was observed while 16 late toxicities occurred (G1: 14 events [87.5%) mainly G1 breast fibrosis). …”
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    Five-year oncological outcome after a single fraction of accelerated partial breast irradiation in the elderly
  17. 21897
    “…The prognosis of MSI-H tumors was similar to that of MSS tumors (log-rank test, P=0.797, the hazard ratio for MSI-H was adjusted by age, sex, pT stage, and the number of metastatic LNs, 0.932; 95% confidence interval, 0.423–2.054; P=0.861). …”
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    Clinical Implications of Microsatellite Instability in Early Gastric Cancer
  18. 21898
    “…Research was focused on the photocatalytic process involving visible light (UVA and natural sunlight) and TiO(2) catalysts modified by different metals (Ag, Pt, Pd, Au). Photocatalytic oxidation showed the lowest efficiency, while in combining ozone with catalysis and photocatalysis process, degradation efficiency and toxicity removal were improved. …”
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    Comparison of radical-driven technologies applied for paraben mixture degradation: mechanism, biodegradability, toxicity and cost assessment
  19. 21899
    “…Final histopathology report revealed moderately differentiated adenocarcinoma of GB invading serosa (pT3) with negative margins and 4 out of 14 lymph nodes showed presence of metastases. …”
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    Outcome of Robot-Assisted Radical Cholecystectomy in a High-Volume Tertiary Cancer Center in India
  20. 21900
    “…This molecular classification was associated with pathological stage (P<0.01), pT stage (P=0.04), pN stage (P<0.01), the grade of tumor budding (P=0.04), and maspin expression in both the tumor core (P=0.04) and the invasion front (P<0.01). …”
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    Immunohistochemical-based molecular subtyping of colorectal carcinoma using maspin and markers of epithelial-mesenchymal transition
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