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22101por Müller, T., Demes, M., Lehn, A., Köllermann, J., Vallo, S., Wild, P. J., Winkelmann, R.“…RESULTS: Our study showed a significant correlation of immune cell infiltrate and pT stage with overall survival. Therefore, in a subset of tumors, PD-L1 staining was applied. …”
Publicado 2021
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22102“…Accordingly, this case was diagnosed as ASC of Stage IIIC (pT4N2M0) and the adjuvant chemotherapy FOLFOX was recommended, while unfortunately the patient refused it for personal reasons. …”
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22103por Cai, Yubo, Chen, Zequn, Liang, Yutong, Liao, Yuehua, Wu, Yuanwei, Huang, Junqiang, Huang, Zhizhen, Li, Ronggang, Chen, Jiewei“…RESULTS: Statistical analysis revealed that CFIm25 expression was significantly associated with vascular invasion (P=0.000), serous invasion (P=0.007), pT stage (P=0.016), and clinical stage (P=0.007). …”
Publicado 2021
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22104“…Compared with males, females more often had age ≥75 years (55.1% vs. 44%), right-sided colon cancer (56.8% vs. 45.4%), and more advanced pT stage cancer (75.5% vs. 72%). In addition, we found that females had better OS than males and that sex could be an independent factor of OS in T1-3N0M0 (Stage I-II) colon cancer (regardless of right/left-sided tumour) and T1-2N0M0 (Stage I) rectal cancer (each HR <1, each P<0.05). …”
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22105por Wu, Shuiyan, Li, Weixi, Bai, Zhenjiang, Huang, Saihu, Yang, Daoping, Chen, Hongmei, Li, Ying, Liu, Ying, Lv, Haitao“…Novel compound heterozygous mutations of the TRMT5 gene were detected, which were c.881A>C (p.E294A) from her mother and c.1218G>C (p.Q406H) and c.1481C>T (p.T494M) from her father. CONCLUSION: The newly emerged clinical features and mutations of this patient provide useful information for further exploration of genotype–phenotype correlations in COXPD26.…”
Publicado 2022
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22106“…Besides, intima-media thickness (IMT) of common carotid artery (465.84 μm), pulse wave velocity (PWV) (8.09 m/s), pressure of turning point 1 from isovolumic contraction phase to ejection phase (PT1) (126.5 mmHg), arterial enhancement pressure (AP) (6.14 mmHg), and arterial pressure enhancement index (8.58%) were all significantly higher than those of the normal control group (P < 0.05). …”
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22107por Anceschi, Umberto, Flammia, Rocco Simone, Mattevi, Daniele, Tufano, Antonio, Brassetti, Aldo, Ferriero, Maria Consiglia, Tuderti, Gabriele, Misuraca, Leonardo, Bove, Alfredo Maria, Mastroianni, Riccardo, Marsiliani, Davide, Puglisi, Marco, Cai, Tommaso, Leonardo, Costantino, Gallucci, Michele, Malossini, Gianni, Luciani, Lorenzo Giuseppe, Simone, Giuseppe“…On multivariable analysis, age (HR 1.04; 95% CI 1.01–1.08) and trifecta (HR 0.34; 95% CI 0.15–0.76) were independent predictors of OS while pT stage (HR 1.95; 95% CI 0.45–8.43) and trifecta (HR 0.33; 95% CI 0.16–0.67) were predictors of CSS (each p < 0.01). …”
Publicado 2022
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22108por Morabito, Alessandro, Manzo, Anna, Montanino, Agnese, Rachiglio, Anna Maria, Sforza, Vincenzo, Pasquale, Raffaella, Costanzo, Raffaele, Maiello, Monica R, Sandomenico, Claudia, Gallo, Marianna, Palumbo, Giuliano, De Luca, Antonella, La Rocca, Antonello, Martucci, Nicola, De Cecio, Rossella, Picone, Carmine, Lastoria, Secondo, Normanno, Nicola“…Extremely low levels of EGFR p.T790M were detected at progression. Based on preclinical data suggesting activity of osimertinib against EGFR exon-20 insertions, the MTB recommended treatment with brain and bone radiotherapy and osimertinib. …”
Publicado 2022
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22109“…A discordant protease inhibitor mutation/wild-type T74PT in plasma but not in cerebrospinal fluid indicated poor central nervous system penetration due to the selective pressure of drug therapy. …”
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22110por Canaff, Lucie, Guarnieri, Vito, Kim, Yoojung, Wong, Betty Y L, Nolin-Lapalme, Alexis, Cole, David E C, Minisola, Salvatore, Eller-Vainicher, Cristina, Cetani, Filomena, Repaci, Andrea, Turchetti, Daniela, Corbetta, Sabrina, Scillitani, Alfredo, Goltzman, David“…Two novel (p.I383M and p.T386S) and one previously reported (p.Y394S) heterozygous GCM2 variants that lie within a C-terminal conserved inhibitory domain were identified in three affected individuals of the hyperparathyroid families. …”
Publicado 2022
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22111por Murokawa, Takahiro, Okabayashi, Takehiro, Oishi, Kazuyuki, Sui, Kenta, Tabuchi, Motoyasu, Iwata, Jun“…CASE PRESENTATION: A 70-year-old male patient with DTC who had previously undergone total thyroidectomy (pT3N1bM0 Stage IV) received radioiodine treatment at our facility. …”
Publicado 2022
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22112por Lei, Jie, Teng, Xuan, Wang, Yongfei, Jiang, Xiaokang, Zhao, Huanhuan, Zheng, Xiaoming, Ren, Yulong, Dong, Hui, Wang, Yunlong, Duan, Erchao, Zhang, Yuanyan, Zhang, Wenwei, Yang, Hang, Chen, Xiaoli, Chen, Rongbo, Zhang, Yu, Yu, Mingzhou, Xu, Shanbin, Bao, Xiuhao, Zhang, Pengcheng, Liu, Shijia, Liu, Xi, Tian, Yunlu, Jiang, Ling, Wang, Yihua, Wan, Jianmin“…Molecular cloning revealed that the FLO19 allele encodes a plastid‐localized pyruvate dehydrogenase complex E1 component subunit α1 (ptPDC‐E1‐α1) that is expressed in all rice tissues. …”
Publicado 2021
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22113por Khusun, Helda, Februhartanty, Judhiastuty, Anggraini, Roselynne, Mognard, Elise, Alem, Yasmine, Noor, Mohd Ismail, Karim, Norimah, Laporte, Cyrille, Poulain, Jean-Pierre, Monsivais, Pablo, Drewnowski, Adam“…OBJECTIVE: To examine the diversity of protein food sources, in both animal and plant, across diverse socio-demographic groups in Indonesia as compared to Malaysia. DESIGN: The SCRiPT (Socio Cultural Research in Protein Transition) study was based on population-based samples recruited in Indonesia (N = 1665) and in Malaysia (N = 1604). …”
Publicado 2022
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22114por Grammatica, Alberto, Tomasoni, Michele, Fior, Milena, Ulaj, Emanuela, Gualtieri, Tommaso, Bossi, Paolo, Battocchio, Simonetta, Lombardi, Davide, Deganello, Alberto, Mattavelli, Davide, Nicolai, Piero, Girardi, Fabio, Piazza, Cesare“…At multivariable analysis, age, immunosuppression, pT3-T4 categories and a high burden of nodal disease (> 2 NM) confirmed to be independent risk factors, whereas adjuvant radiotherapy was independently associated with better outcome. …”
Publicado 2021
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22115“…This study presents the Claim Pre-Training (Claim-PT) framework, a generic pre-training model that first trains on the entire pediatric claims dataset, followed by a discriminative fine-tuning on each population-specific task. …”
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22116por Ghadami, Ladan, Hasibi, Mehrdad, Asadollahi-Amin, Ali, asanjarani, Behzad, Farahmand, Mohammad, Abdollahi, Hamed“…Moreover, the estimated median of partial thromboplastin time (PTT) and Prothrombin time (PT) in patients did not change after CP therapy (p > 0.05). …”
Publicado 2022
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22117AKT1 and PIK3CA activating mutations in Moroccan bladder cancer patients´ biopsies and matched urinepor El Ahanidi, Hajar, El Azzouzi, Meryem, Arrouchi, Housna, Alaoui, Chaimae Hafidi, Tetou, Mohammed, Bensaid, Mounia, Oukabli, Mohamed, Ameur, Ahmed, Al Bouzidi, Abderrahmane, El Mzibri, Mohammed, Attaleb, Mohammed“…RESULTS: AKT1 alterations were poorly detected. Only one patient with pT1 stage and high-grade tumour carried the E17K mutation. …”
Publicado 2022
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22118“…OBJECTIVE: This study aimed to analyze the effects of transcutaneous electrical acupoint stimulation (TEAS) on the immune function in patients with pulmonary tuberculosis (PT) and the inflammatory response following one-lung ventilation surgery by comparing the levels of inflammatory mediators, such as tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), and interleukin 8 (IL-8); T lymphocyte subsets, including CD3(+), CD4(+), CD8(+), and CD4(+)/CD8(+) cells; and natural killer cells (NK cells). …”
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22119por Baz, Mohamed M., Selim, Abdelfattah, Radwan, Ibrahim Taha, Alkhaibari, Abeer Mousa, Khater, Hanem F.“…Viola odorata, Anethum graveolens, T. vulgaris, and N. sativa provide 100% adult mortalities PT with 10, 25, 20, and 25%. The mortality percentages of the adults subjected to 10% of oils (H group) were 48.89%, 88.39%, 63.94%, 51.54%, 92.96%, 44.44%, 72.22%, and 100% for A. sativum, An. graveolens, C. sinensis, F. vulgare, N. sativa, S. officinalis, T. vulgaris, and V. odorata, respectively. …”
Publicado 2022
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22120por Tang, Xiujun, Chen, Zheng, Shen, Xiaoxia, Xie, Tian, Wang, Xiaohong, Liu, Taixiang, Ma, Xiaolu“…Genetic testing showed a pathogenic variant at exon 2 of the PTPN11 gene with c.124A > G (p.T42A). Respiratory distress was deteriorated with progressive chylothorax. …”
Publicado 2022
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