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22601por Mandel, Philipp, Hoeh, Benedikt, Preisser, Felix, Wenzel, Mike, Humke, Clara, Welte, Maria-Noemi, Jerrentrup, Inga, Köllermann, Jens, Wild, Peter, Tilki, Derya, Haese, Alexander, Becker, Andreas, Roos, Frederik C., Chun, Felix K. H., Kluth, Luis A.“…Patients with preoperative systemic therapy (n=19), metastases (cM1, n=5), and locally progressed PCa (pT4 or pN1, n=50) were excluded from analyses. Histopathological features, including total weight of the prostate and specific tumor weight, were recorded by specialized uro-pathologists. …”
Publicado 2021
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22602por Ricci, Jacob C., Hsi, Wen C., Su, Zhong, Mund, Karl, Dawson, Robert, Indelicato, Daniel J.“…Clinically, we use a two‐dimensional (2D) gamma index analysis to obtain the passing rate. The IBA MatriXX PT 2D detection array with finite size ionization chamber was utilized. …”
Publicado 2021
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22603por Barata, Carolina, Rodrigues, Ana Maria, Canhão, Helena, Vinga, Susana, Carvalho, Alexandra M“…METHODS: A data mining approach based on joint models for the survival analysis of the biologic therapy failure is proposed, which considers the information of both baseline and time-varying variables extracted from the electronic medical records of SpA patients from the database, Reuma.pt. RESULTS: Our results show that being a male, starting biologic therapy at an older age, having a larger time interval between disease start and initiation of the first biologic drug, and being human leukocyte antigen (HLA)–B27 positive are indicators of a good prognosis for the biological drug survival; meanwhile, having disease onset or biologic therapy initiation occur in more recent years, a larger number of education years, and higher values of C-reactive protein or Bath Ankylosing Spondylitis Functional Index (BASFI) at baseline are all predictors of a greater risk of failure of the first biologic therapy. …”
Publicado 2021
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22604por Viglialoro, Rita, Esposito, Enrica, Zanca, Roberta, Gessi, Marco, Depalo, Tommaso, Aghakhanyan, Gayane, Bartoli, Francesco, Sollini, Martina, Erba, Paola Anna“…We present a case of a 73-year gentleman diagnosed with prostate adenocarcinoma and surgically treated (pT3bN1Mx, Gleason Score of 9) in February 2016. …”
Publicado 2021
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22605“…Negative correlations between free T3 levels and PT, serum bilirubin and LDL serum levels in children with CLD2 (r= -0.992) (r= -0.902) and (r= -0.946) CONCLUSION: Acute and chronic liver diseases affect thyroid function in children and is correlated with the disease severity.…”
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22606“…Similar results were shown in Model I (adjusted for age, sex and ethnicity) and in Model II (fully adjusting for age, ethnicity, sex, acute kidney injury stage, CHF, renal disease, stroke, malignancy, respiratory failure, pneumonia, sodium, potassium, chloride, BUN, PT, WBC, pH, creatinine, albumin, glucose, bicarbonate, vasopressor use, diastolic blood pressure, respiration rate, temperature, the Elixhauser Comorbidity Index, SOFA score and SAPSII score). …”
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22607“…The secondary outcomes are the comparison between GS upgrading and non-upgrading group, GS upgrading and high-risk PCa (ISUP GG ≥ 3 or ≥ pT3a) predictability of preoperative clinical factors. …”
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22608First case of lung cancer with pneumoconiosis and endobronchial leiomyoma complicating the diagnosispor Takahara, Yutaka, Yamamura, Kouichi, Motono, Nozomu, Oikawa, Taku, Uramoto, Hidetaka, Mizuno, Shiro“…He was, thus, diagnosed with squamous cell lung carcinoma (pT2bN0M0, pStage IIA). CONCLUSIONS: We report a patient with lung cancer and coexistence of a rare endobronchial leiomyoma and pneumoconiosis, who underwent surgery after preoperative evaluation using EBUS-TBNA.…”
Publicado 2021
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22609“…RESULTS: After blood transfusion, serum tumor necrosis interleukin- (IL-) 6, IL-10, factor-α (TNF-α), and C-reactive protein (CRP) decreased in both cohorts, with lower parameters in CG (P < 0.05); the stress indexes, adrenocortical hormone (ACTH), adrenaline (AD), norepinephrine (NE), and cortisol (Cor) increased, especially in CG (P < 0.05); prothrombin time (PT), thrombin time (TT), and activated partial prothrombin time (APTT) in CG were lower than those in OG, and FIB was higher than that in OG with significant differences between two cohorts (all P < 0.05). …”
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22610por Van Oostendorp, Stefan E., Belgers, H. J. (Eric), Hol, Jeroen C., Doornebosch, Pascal G., Belt, Eric J. Th., Oosterling, Steven J., Kusters, Miranda, Bonjer, H. J. (Jaap), Sietses, Colin, Tuynman, Jurriaan B., Boerma, E. J., Creemers, D., Graaf, E. J. De, van der Hoeven, J. A. B., Sosef, M. N., Stockmann, H. B. A. C., van der Stok, E. P., Vuylsteke, R. C. L. M.“…Cox proportional hazards regression revealed procedural experience to be an independent factor in multivariate analysis next to advanced stage (ycMRF+, pT3‐4, pN+) and pelvic sepsis. Corrected analysis projected the 3‐year local recurrence rates to be 9.7%, 3.3% and 3.5% for the implementation, continued adoption and prolonged experience cohorts, respectively. …”
Publicado 2021
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22611por Chen, Zijin, Gao, Chenni, Yu, Haijin, Lu, Lin, Liu, Jialin, Chen, Wei, Xiang, Xiaogang, Hussain, Hafiz Muhammad Jafar, Lee, Benjamin J., Li, Chuanlei, Wei, Wenjie, Huang, Yuhan, Li, Xiang, Fang, Zhengying, Yu, Shuwen, Weng, Qinjie, Ouyang, Yan, Hu, Xiaofan, Tong, Jun, Liu, Jian, Lin, Li, Liu, Mingyu, Xu, Xiaoman, Liu, Dan, Song, Yuan, Lv, Xifeng, Zha, Yixin, Ye, Zhiyin, Jiang, Tingting, Jia, Jieshuang, Chen, Xiaonong, Bi, Yufang, Xue, Jun, Chen, Nan, Hu, Weiguo, He, Cijiang John, Wang, Huiming, Liu, Jun, Xie, Jingyuan“…Using forward stepwise Cox regression analysis, we found eight independent risk factors for AKI including decreased platelet level, lower albumin level, lower phosphorus level, higher level of lactate dehydrogenase (LDH), procalcitonin, C-reactive protein (CRP), urea, and prothrombin time (PT) on admission. For every 0.1 mmol/L decreases in serum phosphorus level, patients had a 1.34-fold (95% CI 1.14–1.58) increased risk of AKI. …”
Publicado 2021
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22612por Sieroń, Karolina, Knapik, Katarzyna, Onik, Grzegorz, Romuk, Ewa, Birkner, Ewa, Kwiatek, Sebastian, Sieroń, Aleksander“…Material and Methods: Forty rats were randomly divided into four equal groups, namely, a control group, a group exposed to low-frequency electromagnetic fields (LF-EMFs; frequency: 50 Hz; intensity: 10 kV/m; magnetic induction: 4.3 pT), a group exposed to radiofrequency electromagnetic fields (RF-EMFs) emitted by mobile phones (frequency: 900 MHz), and a group exposed simultaneously to LF-EMFs and RF-EMFs emitted by mobile phones. …”
Publicado 2021
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22613por Marques, Fernanda, Sousa, Sílvia A., Leitão, Jorge H., Morais, Tânia S., Le Gal, Yann, Lorcy, Dominique“…These compounds feature square planar geometries, as that for cisplatin the Pt(II)-based compound in clinical use as chemotherapeutic drug. …”
Publicado 2021
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22614por Zhu, Shaojin, Zhang, Gengxin, You, Qi, Li, Fei, Ding, Boying, Liu, Feng, Ma, Tongjun“…There were no significant differences between the SS group and NSS group in terms of intraoperative blood loss, postoperative hospital stay, post-surgical pathologic TNM classification (pTNM), post-surgical pathologic tumor classification (pT), post-surgical pathologic extent of lymph node involvement (pN), and total number of dissected lymph nodes. …”
Publicado 2021
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22615por Zvizdic, Zlatan, Milisic, Emir, Ibisevic, Nermina, Pasic, Irmina Sefic, Vranic, Semir“…An appendiceal carcinoid (well-differentiated neuroendocrine tumor, European Neuroendocrine Tumor Society stage pT2) was incidentally detected during histological examination of the appendix. …”
Publicado 2021
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22616por Zhang, Yun, Wang, Jie, Liu, Yong-Mei, Chen, Yin-Ying, Yang, Xiao-Chen, Duan, Lian“…The LVEF and LVFS values significantly increased, the myocardium infarct size and fibrosis significantly decreased, the values of lipid metabolism indexes and blood viscosity indexes significantly reduced in the HQ + DS treatment group vs HQ or DS single treatment (P < 0.05); the LVEDd, LVEDs, and the CSA values significantly reduced in HQ single and HQ + DS treatment groups vs MI group (P < 0.05); the coagulation index (APTT, PT, TT, and FIB) values decreased significantly in the DS single and HQ + DS treatment groups vs MI group (P < 0.05). …”
Publicado 2021
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22617por Li, Di, Deng, Chaoqiang, Zheng, Qiang, Fu, Fangqiu, Wang, Shengping, Li, Yuan, Chen, Haiquan, Zhang, Yang“…Subgroup analyses revealed both adjuvant chemotherapy and adjuvant chemoradiotherapy were significantly associated with superior survival for stage pT2-4 (HR=0.176, 95%CI:0.053-0.578, p=0.004; and HR=0.115, 95%CI:0.033-0.405, p=0.001) and pure SCLC patients (HR=0.182, 95%CI:0.067-0.494, p=0.001; and HR=0.181, 95%CI:0.071-0.465, p<0.001). …”
Publicado 2021
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22618por de Jesus, Joyce de Cassia Rosa, Murari, Ariene Soares de Pinho, Radloff, Katrin, de Moraes, Ruan Carlos Macêdo, Figuerêdo, Raquel Galvão, Pessoa, Ana Flavia Marçal, Rosa-Neto, José César, Matos-Neto, Emídio Marques, Alcântara, Paulo S. M., Tokeshi, Flavio, Maximiano, Linda Ferreira, Bin, Fang Chia, Formiga, Fernanda Bellotti, Otoch, José P., Seelaender, Marilia“…RESULTS: For CC we found opposite modulation in ScAT and PtAT for the gene expression of TLR4, Caspase-1 (cachectic group) and for NF-κB p50, NF-κB p65, IL-1β. …”
Publicado 2021
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22619por Thielemans, Laurence, Peerawaranun, Pimnara, Mukaka, Mavuto, Paw, Moo Kho, Wiladphaingern, Jacher, Landier, Jordi, Bancone, Germana, Proux, Stephane, Elsinga, Henrike, Trip-Hoving, Margreet, Hanboonkunupakarn, Borimas, Htoo, Tha Ler, Wah, Thaw Shee, Beau, Candy, Nosten, Francois, McGready, Rose, Carrara, Verena I.“…Given high levels of pathological jaundice in the first 24 hours and overall high NH burden, guidelines changes were implemented including preventive PT for all neonates <35 weeks and for those 35–37 weeks with risk factors.…”
Publicado 2021
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22620por Galata, Christian, Ronellenfitsch, Ulrich, Weiß, Christel, Blank, Susanne, Reißfelder, Christoph, Hardt, Julia“…METHODS: A retrospective analysis of patients with gastrectomy for pT1–4 gastric cancer between October 1972 and February 2014 at our institution was performed. …”
Publicado 2020
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