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22941por Bornemann, Lea, Schuster, Marc, Schmitz, Saskia, Sobczak, Charlyn, Bessen, Clara, Merz, Simon F., Jöckel, Karl-Heinz, Haverkamp, Thomas, Gunzer, Matthias, Göthert, Joachim R.“…Because of a detected CSF3R (p.T618I) mutation and constitutional symptoms treatment with ruxolitinib was initiated. …”
Publicado 2020
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22942por Zheng, Shaoli, Zhong, Zhaoming, Zhu, Qingan, Li, Zongze, Zhu, Siyuan, Yao, Xinqiang, Zheng, Shuai, Liao, Congrui, Zhu, Yongjian, Chen, Jianting“…In the L5 IS group, pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), lumbar lordosis (LL), and L5 incidence (L5I) were positively associated with slippage rate (SR), but the lumbosacral angle (LSA) was negatively associated with SR (P < 0.01). …”
Publicado 2020
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22943por Ottaiano, Alessandro, Normanno, Nicola, Facchini, Sergio, Cassata, Antonino, Nappi, Anna, Romano, Carmela, Silvestro, Lucrezia, De Stefano, Alfonso, Rachiglio, Anna Maria, Roma, Cristin, Maiello, Monica R., Scala, Stefania, Delrio, Paolo, Tatangelo, Fabiana, Di Mauro, Annabella, Botti, Gerardo, Avallone, Antonio, Nasti, Guglielmo“…G3), side of primary tumour (left vs. right), pT, and pN. At the median follow-up of 25.6 months, there were 77 deaths in KRAS-mutated patients and 94 in wild-type patients. …”
Publicado 2020
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22944por Manica, Santiago Rodrigues, Sepriano, Alexandre, Pimentel-Santos, Fernando, Gouveia, Nélia, Barcelos, Anabela, Branco, Jaime C., Bernardes, Miguel, Ferreira, Raquel Miriam, Vieira-Sousa, Elsa, Barreira, Sofia, Vinagre, Filipe, Roque, Raquel, Santos, Helena, Madeira, Nathalie, Rovisco, João, Daniel, Alexandra, Ramiro, Sofia“…METHODS: Patients with axSpA from the Rheumatic Diseases Portuguese Register (ReumaPt), who discontinued their first TNFi and started the second TNFi between June 2008 and May 2018, were included. …”
Publicado 2020
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22945“…Blood concentrations of AST and ALT were measured using the Vitros 250 device while blood APTT, PT and TT concentrations were measured using commercial diagnostics kits. …”
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22946por Matsuo, Mikiko, Hatano, Yuichiro, Imaizumi, Yuko, Kuroda, Takahiro, Arai, Toshinori, Tomita, Hiroyuki, Matsuhashi, Nobuhisa, Yoshida, Kazuhiro, Hara, Akira“…In addition, TP53 mutational analysis detected an identical missense mutation (p.T211I) between the two intestinal cancers. Moreover, further molecular genetic work-up revealed that both small intestinal and colon adenocarcinomas harbored an identical missense mutation (p.G12D) of KRAS gene. …”
Publicado 2020
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22947por Pizzi, Roberto, Gini, Giancarlo, Caiano, Lucia, Castelli, Beniamino, Dotan, Noga, Magni, Federica, Virano, Alexandra, Roveda, Andrea, Bertù, Lorenza, Ageno, Walter“…After multivariate analysis, results were unchanged (Odds Ratio 1.00 95%CI: 0.99–1.00, p = 0.21). PT and aPTT values were also similar between the two groups, fibrinogen levels were higher in COVID19 than in non-COVID19 patients (684 and 496 mg/dL, respectively, p < 0.0001). …”
Publicado 2020
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22948“…The post-surgery pathology showed that there was squamous cell carcinoma in the upper left lung (pT2bN0M0 p Phase IIA) and no cancer metastasis with the lymph nodes. …”
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22949por Meulemans, Jeroen, Demarsin, Hannelore, Debacker, Jens, Batailde, Gaël, Mennes, Tillo, Laenen, Annouschka, Goeleven, Ann, Neyt, Peter, Vanclooster, Christophe, Vauterin, Tom, Delaere, Pierre, Huvenne, Wouter, Vander Poorten, Vincent“…Achieving postoperative functional speech proved most likely in patients with smaller tumors (lower pT classification) and free section margins. Conclusion: Substantial complication rates and favorable functional outcomes are reported after STL.…”
Publicado 2020
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22950por Yeh, Yu-Hsin, Hsieh, Meng-Ying, Lee, Wen-I, Huang, Jing-Long, Chen, Li-Chen, Yeh, Kuo-Wei, Ou, Liang-Shiou, Yao, Tsung-Chieh, Wu, Chao-Yi, Lin, Syh-Jae“…Six novel mutations were detected: c.504G>T [p.K168N], c.895-2A>G [p.Del K290 fs 23(*)], c.910T>G [p.F304V], c.1132T>C [p.T334H], c.1562A>T [p.D521V], and c.1957delG [Del p.D653 fs plus 45 a.a.]. …”
Publicado 2020
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22951por Rahman, Proton, Baer, Philip, Keystone, Ed, Choquette, Denis, Thorne, Carter, Haraoui, Boulos, Chow, Andrew, Faraawi, Rafat, Olszynski, Wojciech, Kelsall, John, Rampakakis, Emmanouil, Lehman, Allen J., Nantel, Francois“…A significant decrease in baseline disease duration and disease activity parameters (DAS, TJC, SJC, HAQ, AM stiffness, MDGA, PtGA, CRP, ESR) was observed over time. Treatment with IFX, GLM- and GLM-IV significantly improved all disease parameters over time. …”
Publicado 2020
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22952por Lu, Xiao-Jie, Yang, Xiao-Jun, Sun, Jing-Yu, Zhang, Xin, Yuan, Zhao-Xin, Li, Xiu-Hui“…In LASSO logistic regression and filter methods, fibroscan results, platelet count, alanine transaminase (ALT), prothrombin time (PT), type III procollagen aminoterminal peptide (PIIINP), type IV collagen, laminin, hyaluronic acid (HA) and diameter of spleen vein were finally selected as input variables in FibroBox. …”
Publicado 2020
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22953por Engl, Tobias, Mandel, Philipp, Hoeh, Benedikt, Preisser, Felix, Wenzel, Mike, Humke, Clara, Welte, Maria, Köllermann, Jens, Wild, Peter, Deuker, Marina, Kluth, Luis A., Roos, Frederik C., Chun, Felix K. H., Becker, Andreas“…. >3 and <6 months after diagnosis for the following oncological endpoints: pT-stage, ISUP grading, probability of a positive surgical margin, probability of lymph node invasion (LNI), lymphovascular invasion (LVI), and perineural invasion (pn) in patients with intermediate- and high-risk PCa. …”
Publicado 2020
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22954por Long, Xin, Zhang, Zhanguo, Zou, Wenbin, Ling, Jianmin, Li, Donghui, Jing, Liang, Yu, Shanshan, Zou, Xiaojing, Bian, Yi, Wu, Wenjuan, Li, Shusheng, Fang, Minghao“…Raised values of d-dimer and FDP were measured in all patients, especially in non-survivors, who had longer PT, APTT, INR, as well as TT, and lower PTA and AT compared to survivors. …”
Publicado 2020
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22955“…Sensitivity analysis demonstrated that in order for SAM to be the less expensive option, the cost per 15-min session of PT would need to be greater than $88, or SAM would need to be priced at less than or equal to $2276. …”
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22956por Geers, Joachim, Jaekers, Joris, Topal, Halit, Aerts, Raymond, Vandoren, Cindy, Vanden Boer, Guy, Topal, Baki“…Independent predictors of OS were locoregional lymph node metastasis (LNM) (risk ratio (RR) 2.12, confidence interval (CI) 1.19–3.81, p = 0.011), patient American Society of Anesthesiologists (ASA) physical status classification system > 2 (RR 2.10, CI 1.03–4.26, p = 0.043), and depth of tumour penetration (pT) > 2 (RR 2.58, CI 1.03–6.30, p = 0.043). The presence of locoregional LNM (RR 2.95, CI 1.51–5.90, p = 0.002) and caudate lobe resection (RR 2.19, CI 1.01–5.14, p = 0.048) were found as independent predictors of DFS. …”
Publicado 2020
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22957por Koudriavtseva, Tatiana, Stefanile, Annunziata, Fiorelli, Marco, Lapucci, Caterina, Lorenzano, Svetlana, Zannino, Silvana, Conti, Laura, D’Agosto, Giovanna, Pimpinelli, Fulvia, Di Domenico, Enea Gino, Mandoj, Chiara, Giannarelli, Diana, Donzelli, Sara, Blandino, Giovanni, Salvetti, Marco, Inglese, Matilde“…Patients and controls will be tested for either coagulation/complement (C3, C4, C4a, C9, PT, aPTT, fibrinogen, factor II, VIII, and X, D-dimer, antithrombin, protein C, protein S, von-Willebrand factor), soluble markers of endothelial damage (thrombomodulin, Endothelial Protein C Receptor), antiphospholipid antibodies, lupus anticoagulant, complete blood count, viral serological assays, or microRNA microarray. …”
Publicado 2020
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22958por Macchia, Gabriella, Cilla, Savino, Buwenge, Milly, Zamagni, Alice, Ammendolia, Ilario, Zamagni, Claudio, Frezza, Giovanni P, Valentini, Vincenzo, Deodato, Francesco, Morganti, Alessio G“…PATIENTS AND METHODS: In this phase I–II trial, 321 patients with intermediate-high risk BC (pT1-4 with at least one of the following characteristics: pre or perimenopausal status, pN2-3, positive or close margins) were enrolled. …”
Publicado 2020
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22959por Das, Saurav, Plyler-Harveson, T., Santra, Dipak K., Maharjan, Bijesh, Nielson, Kathy A., Harveson, Robert M.“…AMOVA analysis based on ΦPT values showed 87% variation within and 13% among the population with statistical significance (p < 0.05). …”
Publicado 2020
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22960por Wang, Jianyang, Tang, Yu, Jing, Hao, Sun, Guangyi, Jin, Jing, Liu, Yueping, Song, Yongwen, Wang, Weihu, Fang, Hui, Chen, Bo, Qi, Shunan, Ren, Hua, Li, Ning, Tang, Yuan, Lu, Ningning, Yang, Yong, Yu, Zihao, Wang, Shulian, Li, Yexiong“…CONCLUSIONS: Risk Stratification based on age, T stage, ER/PR status and tumor location can stratify patients with pT1–2 N0 breast cancer into subgroups with different risk of LRR. …”
Publicado 2020
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