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23441“…The sagittal imaging parameters including sagittal vertebral axis (SVA),thoracic kyphosis (TK),thoracolumbar kyphosis (TLK),lumbar lordosis (LL),pelvic incidence (PI),pelvic tilt (PT),and sacral slope (SS) before operation,immediately after operation,and the last follow-up of each case were measured and evaluated. …”
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23442por Chou, Shih-Hsiang, Li, Wen-Wei, Lu, Cheng-Chang, Lin, Kun-Ling, Lin, Sung-Yen, Shen, Po-Chih, Tien, Yin-Chun, Huang, Hsuan-Ti“…The radiographic assessments included deformity correction and progressive changes in the major curve angle, pelvic tilt (PT) and coronal balance (CB). The correction of deformities was observed postoperatively and at the patient’s 2-year follow-up to test the efficacy of each type of construct. …”
Publicado 2021
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23443por Chen, Zhijian, Song, Jianling, Li, Xinyong, Arango, Jacobo, Cardoso, Juan Andres, Rao, Idupulapati, Schultze-Kraft, Rainer, Peters, Michael, Mo, Xiaohui, Liu, Guodao“…A group of differentially expressed genes (DEGs) involved in Pi uptake and Pi homeostasis were identified, such as genes encoding Pi transporter (PT), purple acid phosphatase (PAP), and multidrug and toxin extrusion (MATE). …”
Publicado 2021
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23444“…Variants in exon 8, 15, 12, and 16 were most prevalent, while the most common variants were c.892G>A (p.A298T) (n = 9), c.139C>T (p.R47W) (n = 3), c.1205C>T(p.A402V) (n = 3), c.1657A>T (p.I553F) (n = 3), c.1679T>C (p.M560T) (n = 3), c.350A>G (p.D117G) (n = 2), c.762C>G (p.C254W) (n = 2), c.782A>G (P.Y261C) (n = 2), and c.1277C>A (p.T426N) (n = 2). Conclusion: Our results reported five CLCN1-related MC patients, which expanded the clinical and genetic spectrum of MC patients in China. …”
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23445por Chaloupka, Michael, Stoermer, Lina, Apfelbeck, Maria, Buchner, Alexander, Wenter, Vera, Stief, Christian G., Westhofen, Thilo, Kretschmer, Alexander“…However, evidence regarding radical prostatectomy (RP) in this setting is still subpar, and the effect of cytoreductive RP on postoperative health-related quality of life (HRQOL) is still unclear. (2) Methods: for the current study, patients with de-novo oligo-metastatic PC (cM1-oligo), defined as ≤5 bone lesions in the preoperative staging, were included, and matched cohorts using the variables age, body-mass index (BMI), and pT-stage were generated. Patient-reported outcome measures (PROMS) were assessed pre- and postoperatively using the validated EORTC-QLQ-C30, IIEF-5, and ICIQ-SF questionnaires. …”
Publicado 2021
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23446por Hengel, Richard L, Metzger, Brian S, Barry Baker, H, Adams, John S, Nathan, Ramesh V, Bhattacharyya, Rishi, Mandel, Richard M, Couch, Kimberly A, Schroeder, Claudia P, Van Anglen, Lucinda J“…METHODS: Records from 18 POICs were queried for GUI pts with ≥1 GNP receiving OPAT from 2018 to 2020. Demographics, pt location prior to OPAT, infection type, year of therapy, and GNP were recorded. …”
Publicado 2021
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23447por Roberto, T.N., de Carvalho, J.A., Beale, M.A., Hagen, F., Fisher, M.C., Hahn, R.C., de Camargo, Z.P., Rodrigues, A.M.“…Analysis of molecular variance (AMOVA) revealed that the total genetic variance (65-66 %) was due to variability among P. brasiliensis complex and P. lutzii (PhiPT = 0.651–0.658, P < 0.0001), supporting a highly structured population. …”
Publicado 2021
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23448por de Carvalho, J.A., Beale, M.A., Hagen, F., Fisher, M.C., Kano, R., Bonifaz, A., Toriello, C., Negroni, R., Rego, R.S. de M., Gremião, I.D.F., Pereira, S.A., de Camargo, Z.P., Rodrigues, A.M.“…AMOVA revealed highly structured clusters (PhiPT = 0.458–0.484, P < 0.0001), with roughly equivalent genetic variability within (46–48 %) and between (52–54 %) populations. …”
Publicado 2021
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23449por Bhimani, Rohan, Shahriarirad, Reza, Ranjbar, Keivan, Erfani, Amirhossein, Ashkani-Esfahani, Soheil“…Furthermore, the pooled complication rates from all studies were similar between the two groups (AIT: 54 patients, 8.26% vs. PT: 55 patients, 6.62%). However, the four studies that prospectively compared AIT and TP techniques showed lesser complications in the AIT group than the TP group. …”
Publicado 2021
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23450por Kasahara, Kenta, Enomoto, Masanobu, Udo, Ryutaro, Tago, Tomoya, Mazaki, Junichi, Ishizaki, Tetsuo, Yamada, Tesshi, Nagakawa, Yuichi, Katsumata, Kenji, Tsuchida, Akihiko“…In the multivariate analysis of the HS-GPS model, age, pT, pN, and HS-GPS of 2 compared to HS-GPS of 0 (2 vs 0; hazard ratio [HR], 2.638; 95% confidence interval [CI], 1.046–6.650; P = 0.04) were identified as independent prognostic predictors of OS. …”
Publicado 2022
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23451por Fitzal, Florian, Bolliger, Michael, Dunkler, Daniela, Geroldinger, Angelika, Gambone, Luca, Heil, Jörg, Riedel, Fabian, de Boniface, Jana, Andre, Camilla, Matrai, Zoltan, Pukancsik, Dávid, Paulinelli, Regis R., Ostapenko, Valerijus, Burneckis, Arvydas, Ostapenko, Andrej, Ostapenko, Edvin, Meani, Francesco, Harder, Yves, Bonollo, Marta, Alberti, Andrea S. M., Tausch, Christoph, Papassotiropoulos, Bärbel, Helfgott, Ruth, Heck, Dietmar, Fehrer, Hans-Jörg, Acko, Markus, Schrenk, Peter, Trapp, Elisabeth K., Gunda, Pristauz-Telsnigg, Clara, Paliczek, Montagna, Giacomo, Ritter, Mathilde, Blohmer, Jens-Uwe, Steffen, Sander, Romics, Laszlo, Morrow, Elizabeth, Lorenz, Katharina, Fehr, Mathias, Weber, Walter Paul“…The BCS/OBCI group had significantly smaller tumors and smaller resection margins compared with OBCII (pT1: 50% vs. 37%, p = 0.002; proportion with margin <1 mm: 17% vs. 6%, p < 0.001). …”
Publicado 2021
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23452por Saad, Eddy, Semaan, Karl, Kawkabani, Georges, Massaad, Abir, Salibv, Renee Maria, Mekhael, Mario, Fakhoury, Marc, Karam, Krystel Abi, Jaber, Elena, Ghanem, Ismat, Lafage, Virginie, Skalli, Wafa, Rachkidi, Rami, Assi, Ayman“…ASD were further divided into 34 ASD-sag (with PT > 25° and/or SVA >5 cm and/or PI-LL >10°), 32 ASD-hyperTK (with only TK >60°), and 27 ASD-front (with only frontal malalignment: Cobb >20°). …”
Publicado 2022
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23453por Kuriyama, Kengo, Sohda, Makoto, Saito, Hideyuki, Ubukata, Yasunari, Nakazawa, Nobuhiro, Hara, Keigo, Sakai, Makoto, Sano, Akihiko, Ogawa, Hiroomi, Sano, Takaaki, Yasuda, Shigeo, Ishikawa, Hitoshi, Shirabe, Ken, Saeki, Hiroshi“…The tumors were diagnosed as pathological stage IA (pT1aN0M0) according to the TNM criteria. Moreover, pathological examinations showed severe fibrosis of the previously irradiated tissues compared to the normal esophagus located outside of the irradiation field. …”
Publicado 2022
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23454por Rondung, Elisabet, Leiler, Anna, Sarkadi, Anna, Bjärtå, Anna, Lampa, Elin, Löfving, Sandra Gupta, Calam, Rachel, Oppedal, Brit, Keeshin, Brooks, Warner, Georgina“…A process for Decision-making after Pilot and feasibility Trials (ADePT) was used to support systematic decision-making in moving forward with the trial. …”
Publicado 2022
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23455por Takebayashi, Takashi, Takahashi, Kayoko, Okita, Yuho, Kubo, Hironobu, Hachisuka, Kenji, Domen, Kazuhisa“…RESULTS: Overall, significant differences of the group × severity interaction were found in most of the outcomes, including FMA-proximal (p = 0.038, η(2) = 0.13), WMFT-PT (p = 0.021, η(2) = 0.17), and WMFT-FAS (p = 0.045, η(2) = 0.14). …”
Publicado 2022
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23456“…Based on postoperative pathology, the rates of PSMs in the entire cohort and in those with stage pT2 disease were 26.6% and 8.5%, respectively. The continence and potency rates at 12 months were 88.3% and 56.4%, respectively. …”
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23457por Kurien, Surupa S, David, Regi S, Chellappan, Ajitha K, Varma, Ravi P, Pillai, Padmakumar R, Yadev, Induprabha“…On bivariate analyses, the mean values of total leukocyte count (TLC), absolute neutrophil count (ANC), neutrophil-to-lymphocyte ratio (NLR), C-reactive protein (CRP), ferritin, lactate dehydrogenase (LDH), D-dimer at admission, prothrombin time international normalized ratio (PT INR), blood urea nitrogen (BUN), and creatinine were significantly higher in non-survivors than in survivors: mean (SD) 11.9 (7.6) vs 7.5 (4.2) (x10(9)/L), 10.5 (7.4) vs 5.3 (4.1) (x10(9)/L), 11.6 (13.5) vs 3.4 (3.5), 185 (117) vs 48 (85) (mg/L), 829.4 (551.2) vs 323.6 (374.1) (ng/ml), 905.5 (589.1) vs 485.1 (353.9) (U/L), 4.01 (3.53) vs 1.29 (2.08) (µg/ml), 1.21 (0.42) vs 0.99 (0.18), 105.1 (91.4) vs 33.6 (31.0) (mg/dl), 3.6 (4.1) vs 1.1 (1.6) (mg/dl), respectively, p < 0.001. …”
Publicado 2022
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23458por Dagher, Sami, Sulaiman, Abdulrazzaq, Bayle-Bleuez, Sophie, Tissot, Claire, Grangeon-Vincent, Valérie, Laville, David, Fournel, Pierre, Tiffet, Olivier, Forest, Fabien“…In univariate analysis, performance status, pathological stage pT or pN, pleural invasion, histopathological subtype, percentage of tumor necrosis, vasculolymphatic invasion, single-cell invasion, budding and tumor nest size correlated with the percentage of survival at 5 years. …”
Publicado 2022
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23459por Guo, Wei, Yao, Xiaohui, Lan, Siyuan, Zhang, Chi, Li, Hanhan, Chen, Zhuangzhong, Yu, Ling, Liu, Guanxian, Lin, Yuan, Liu, Shan, Chen, Hanrui“…The core target genes included BCL2, MCL1, Myc, PTEN, gsk3b, CASP9, CREB1, MDM2, pt53 and CCND1. Cancer-associated pathways were largely involved in SNKAF mechanisms, including P53, FoxO, and PI3K/Akt signaling pathways, which are closely related to induced-tumor cell apoptosis. …”
Publicado 2022
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23460“…RESULTS: Multivariate Cox regression identified stage, PM, chemotherapy, Age, PT, and radiation_surgery as independent influence factors for cervical carcinoma patients. …”
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