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  1. 23601
    por Jamal, Issra
    Publicado 2020
    “…He is currently status post stem cell transplantation with a good response and the weakness and polyneuropathy improved with PT and OT. POEMS syndrome has major and minor criteria for diagnosis, mandatory major criteria includes polyneuropathy, monoclonal plasma cell proliferative disorder (almost always lambda). …”
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    SAT-LB117 POEMS Syndrome: Rare Presentation of New Onset Diabetes Mellitus
  2. 23602
    “…RESULTS: We observed significant associations with PRS for T1D and percentage BMI/weight change from baseline to the endpoint at P-value threshold=0.0022 (R2=0.02, p=0.03), as well as presence/absence of significant weight gain at PT=0.00015 (R2=0.02, p=0.047). In contrast, we observed no significant associations with PRS for SCZ, BMI, or T2D and AIWG (p>0.05). …”
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    M172. POLYGENIC RISK SCORES ANALYSES IN ANTIPSYCHOTIC-INDUCED WEIGHT GAIN
  3. 23603
    “…Severe group also had significantly abnormal coagulation parameters than non-severe group: prothrombin time (PT) 14.55 (13.40–16.53) s vs. 12.70 (12.15–13.59) s, p = 0.000; international normalized ratio (INR) 1.21 (1.13–1.36) vs. 1.06 (1.01–1.13), p = 0.000; thrombin time (TT) 16.35 (15.69–17.47) s vs. 15.68 (14.79–16.69) s, p = 0.011; D-Dimer 1.05 (0.68–5.90) mg/L vs. 0.42 (0.28–0.79) mg/L, p = 0.000; While the liver function parameter alanine aminotransferase (ALT) and aspartate aminotransferase (AST) didn’t show significance between two groups, ALT 30.80 (19.00–58.30) IU/L vs. 28.80 (15.75–50.15) IU/L, p = 0.487; AST 27.80 (19.30–40.55) IU/L vs. 22.6 (16.7–32.03) IU/L, p = 0.102. …”
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    SARS-CoV-2 induced thrombocytopenia as an important biomarker significantly correlated with abnormal coagulation function, increased intravascular blood clot risk and mortality in COVID-19 patients
  4. 23604
    “…This process was performed at all phases: surgical intervention, all clinical follow-ups, and physical therapy (PT) sessions. RESULTS: A total of 611 patients were included for this investigation. …”
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    Does Graft type affect the Cost of Anterior Cruciate Ligament Reconstruction: A Time-Driven Activity-Based Costing Approach Comparing Hamstring and Bone Patella Bone Autograft
  5. 23605
    “…Results of the resection histopathology revealed an invasive ductal carcinoma, pT3N0M0, stage IIB, HER2 positive. The lady patient received 6 cycles of adjuvant chemotherapy and was subjected to adjuvant trastuzumab therapy for 1 year. …”
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    Human epidermal growth factor receptor 2-positive metastatic breast cancer with novel epidermal growth factor receptor -ZNF880 fusion and epidermal growth factor receptor E114K mutations effectively treated with pyrotinib: A case report
  6. 23606
    “…RESULTS: Among patients with migraine, mean improvements from baseline in MSQ domain scores increased with each successive level of migraine headache day response. On a 100‐pt scale, increases in Role Function‐Restrictive score in EM were 16.8 and 36.0 at the <30% and ≥75% response levels, respectively, and for CM were 10.7 and 46.5. …”
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    Migraine Headache Day Response Rates and the Implications to Patient Functioning: An Evaluation of 3 Randomized Phase 3 Clinical Trials of Galcanezumab in Patients With Migraine
  7. 23607
    “…The EMR was reviewed up to 1 year after the IC. Pt and culture characteristics were recorded. The primary outcome was proportion of pts who developed an ESBLP SI. …”
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    838. Drivers of empiric carbapenem use: How important is history of extended-spectrum beta-lactamase (ESBL) infection?
  8. 23608
    por Nagami, Yasuaki, Sakai, Taishi, Yamamura, Masafumi, Nakatani, Masami, Katsuno, Takayuki, Suekane, Takehisa, Uno, Hironori, Minamino, Hiroaki, Okuyama, Masatsugu, Okamoto, Junichi, Kumamoto, Mitsutaka, Noguchi, Atsushi, Yamamori, Kazuki, Takaishi, Osamu, Ochi, Masahiro, Miyazaki, Takako, Tsuji, Shigetsugu, Ikehara, Hisatomo, Kawaguchi, Koichiro, Hayashi, Tomoyuki, Mannami, Tomohiko, Kakimoto, Kazuki, Naito, Yoshihide, Hashimoto, Satoru, Li, Zhaoliang, Komeda, Yoriaki, Kishino, Takaaki, Yamamoto, Yoshinobu, Iguchi, Mikitaka, Akamatsu, Takuji, Horii, Toshiki, Miura, Ko, Yamashina, Takeshi, Sugihara, Yuusaku, Watanabe, Noboru, Kiyotoki, Shu, Fujii, Ryoji, Murata, Masaki, Ono, Satoshi, Narasaka, Toshiaki, Kitamura, Shinji, Kono, Mitsuhiro, Kato, Motohiko, Kawaratani, Hideto, Tanaka, Kyosuke, Yaoita, Takao, Yamaguchi, Shinjiro, Abe, Keiichiro, Kawamura, Takuji, Kinoshita, Yosuke, Imai, Kenichiro, Fujinami, Haruka, Yada, Tomoyuki, Miyamoto, Hayato, Yoshida, Hisako, Fujiwara, Yasuhiro
    Publicado 2021
    “…On the contrary, the secondary outcomes include the rate of cumulative bleeding, rate of overt haemorrhage (that does not qualify for the definition of haemorrhage after endoscopic polypectomy), incidence of haemorrhage requiring haemostasis during endoscopic polypectomy, intraoperative bleeding during endoscopic colorectal polypectomy requiring angiography, abdominal surgery and/or blood transfusion, total rate of bleeding, risk factors for postoperative bleeding, length of hospital stay, incidence of thromboembolism, prothrombin time-international ratio (PT-INR) 28 days after the surgery, and incidence of serious adverse events. …”
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    Continuous warfarin administration versus heparin bridging therapy in post colorectal polypectomy haemorrhage: a study protocol for a multicentre randomised controlled trial (WHICH study)
  9. 23609
    “…Reduced E-Cadherin expression was linked to higher grade (p = 0.0009), triple negative receptor status (p = 0.0336), and poor prognosis (p = 0.0466) in invasive breast carcinoma of no special type, triple negative receptor status in lobular carcinoma of the breast (p = 0.0454), advanced pT stage (p = 0.0047) and lymph node metastasis in colorectal cancer (p < 0.0001), and was more common in recurrent than in primary prostate cancer (p < 0.0001). …”
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    E-Cadherin expression in human tumors: a tissue microarray study on 10,851 tumors
  10. 23610
    “…Using computational prediction, we identified NF1 p.T700I and NOTCH1 p.V2153M as tumor-associated neoantigens, representing potential therapeutic targets for immunotherapy. …”
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    Comprehensively Exploring the Mutational Landscape and Patterns of Genomic Evolution in Hypermutated Cancers
  11. 23611
    “…Routine and specialized coagulation tests were performed on patients' platelet-poor plasma at the time of study inclusion (day 0), days 3, 7 and at discharge on STAR Max®3 (Diagnostica Stago France) automated coagulation analyzer and included prothrombin time (PT), international normalized ratio (INR) (STA® -NeoPTimal), activated partial thromboplastin time (APTT) (STA® -Cephascreen), fibrinogen (STA® Liquid Fib), D-dimer (STA® LiatestD- Dimer), Protein C (STA Stachrom® Protein C), Protein S (STA® Latest Free Protein S) and Antithrombin (STA® Chrom ATIII). …”
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    A Prospective Study of Specialized Coagulation Parameters in Admitted COVID-19 Patients and Their Correlation With Acute Respiratory Distress Syndrome and Outcome
  12. 23612
    “…Univariate survival analysis showed that RUNX3 expression, EZH2 expression, cN, clinical T (cT), pathological T (pT) and pathological N (pN) were significantly correlated with the 5-year DFS and 5-year OS. …”
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    Combined Detection of RUNX3 and EZH2 in Evaluating Efficacy of Neoadjuvant Therapy and Prognostic Value of Middle and Low Locally Advanced Rectal Cancer
  13. 23613
    por Picetti, Edoardo, Iaccarino, Corrado, Coimbra, Raul, Abu-Zidan, Fikri, Tebala, Giovanni D., Balogh, Zsolt J., Biffl, Walter L., Coccolini, Federico, Gupta, Deepak, Maier, Ronald V., Marzi, Ingo, Robba, Chiara, Sartelli, Massimo, Servadei, Franco, Stahel, Philip F., Taccone, Fabio S., Unterberg, Andreas W., Antonini, Marta Velia, Galante, Joseph M., Ansaloni, Luca, Kirkpatrick, Andrew W., Rizoli, Sandro, Leppaniemi, Ari, Chiara, Osvaldo, De Simone, Belinda, Chirica, Mircea, Shelat, Vishal G., Fraga, Gustavo P., Ceresoli, Marco, Cattani, Luca, Minardi, Francesco, Tan, Edward, Wani, Imtiaz, Petranca, Massimo, Domenichelli, Francesco, Cui, Yunfeng, Malchiodi, Laura, Sani, Emanuele, Litvin, Andrey, Hecker, Andreas, Montanaro, Vito, Beka, Solomon Gurmu, Di Saverio, Salomone, Rossi, Sandra, Catena, Fausto
    Publicado 2022
    “…A little more than half of respondents considered safe a platelet (PLT) count > 100.000/mm(3) [n = 99 (57.9%)] and prothrombin time (PT)/activated partial thromboplastin time (aPTT) < 1.5 times the normal control [n = 85 (49.7%)] in patients needing spinal surgery. …”
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    The acute phase management of spinal cord injury affecting polytrauma patients: the ASAP study
  14. 23614
    “…There was no significant difference between the two groups of patients in terms of upper resection margin, operation time, blood loss, tumor diameter, pT, pN and postoperative hospital stay. The gastric resection volume of the DTR group was much larger than that of the ENGC group, and there was a significant difference between the two (p = 0.000). …”
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    Selection of Digestive Tract Reconstruction After Partial Gastric Sparing Surgery in Patients With Adenocarcinoma of the Esophagogastric Junction of cT(2)-T(3) Stage
  15. 23615
    “…We found a significant impact of high ki-67 (p = 0.002, log-rank) and p53 (p = 0.032, log-rank) expression on decreasing patients’ survival, as well as grade, pT, stage, pattern, and depth of invasion (p < 0.05, log-rank). …”
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    A comprehensive analysis of penile cancer in the region with the highest worldwide incidence reveals new insights into the disease
  16. 23616
    “…RESULTS: The predictive nomogram modle comprised eleven variables: overweight(24-28) defined by body mass index (BMI): [odds ratio (OR): 1.90, 95% confidence interval (CI): 1.19-3.07], adenocarcinoma(OR:3.00, 95% CI: 1.88-4.87), stageIII-IV(OR:2.75, 95%CI: 1.58-4.96), Central venous catheters(CVCs) (OR:4.64, 95%CI: 2.86-7.62), D-dimer levels≥2.06mg/L(OR:5.58, 95%CI:3.54-8.94), PT levels≥11.45sec(OR:2.15, 95% CI:1.32-3.54), Fbg levels≥3.33 g/L(OR:1.76, 95%CI:1.12-2.78), TG levels≥1.37mmol/L (OR:1.88, 95%CI:1.19-2.99), ROS1 rearrangement(OR:2.87, 95%CI:1.74-4.75), chemotherapy history(OR:1.66, 95%CI:1.01-2.70) and radiotherapy history(OR:1.96, 95%CI:1.17-3.29). …”
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    Derivation, validation and assessment of a novel nomogram-based risk assessment model for venous thromboembolism in hospitalized patients with lung cancer: A retrospective case control study
  17. 23617
    por Tafuri, Alessandro, Marchioni, Michele, Cerrato, Clara, Mari, Andrea, Tellini, Riccardo, Odorizzi, Katia, Veccia, Alessandro, Amparore, Daniele, Shakir, Aliasger, Carbonara, Umberto, Panunzio, Andrea, Trovato, Federica, Catellani, Michele, Janello, Letizia M. I., Bianchi, Lorenzo, Novara, Giacomo, Dal Moro, Fabrizio, Schiavina, Riccardo, De Lorenzis, Elisa, Parma, Paolo, Cimino, Sebastiano, De Cobelli, Ottavio, Maiorino, Francesco, Bove, Pierluigi, Crocerossa, Fabio, Cantiello, Francesco, D’Andrea, David, Di Cosmo, Federica, Porpiglia, Francesco, Ditonno, Pasquale, Montanari, Emanuele, Soria, Francesco, Gontero, Paolo, Liguori, Giovanni, Trombetta, Carlo, Mantica, Guglielmo, Borghesi, Marco, Terrone, Carlo, Del Giudice, Francesco, Sciarra, Alessandro, Galosi, Andrea, Moschini, Marco, Shariat, Shahrokh F., Di Nicola, Marta, Minervini, Andrea, Ferro, Matteo, Cerruto, Maria Angela, Schips, Luigi, Pagliarulo, Vincenzo, Antonelli, Alessandro
    Publicado 2022
    “…In LM models, age (p = 0.019), hydronephrosis (p < 0.001), POD-1 AKI (p < 0.001) and pT-stage (p = 0.001) influenced renal function variation (ß 9.2 ± 0.7, p < 0.001) during follow-up. …”
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    Changes in renal function after nephroureterectomy for upper urinary tract carcinoma: analysis of a large multicenter cohort (Radical Nephroureterectomy Outcomes (RaNeO) Research Consortium)
  18. 23618
    “…The diagnosis includes acromegaly in 16 pts, Cushing disease in 10 pts, prolactinomas in 50 pts, non-functioning PA in 37 pts, TSHoma in 1 pt, and gonadotrophinoma in 14 pts. None of those pts had a family history of PA or known syndromes. …”
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    LBMON174 Germline Molecular Genetics Of Pituitary Adenomas
  19. 23619
    “…RACHS1, 10.754, 4.751–24.342, P < 0.001), APTT (1.628, 1.058–2.503, P = 0.027), and PT (2.174, 1.065–4.435, P = 0.033) to be plasma. …”
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    The characteristics of blood transfusion and analysis of preoperative factors associated with intraoperative blood transfusion in congenital heart surgery: a case–control study
  20. 23620
    “…METHODS: We analysed data from the EpiReumaPt study (n = 10,661), that included a representative sample of the Portuguese population. …”
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    Prevalence of and factors associated with unmanageable pain levels in people with knee or hip osteoarthritis: a cross-sectional population-based study
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