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7761por Artsi, Hanna, Gurt, Irina, El-Haj, Madi, Müller, Ralph, Kuhn, Gisela A., Ben Shalom, Gal, Cohen-Kfir, Einav, Abramowitz, Eva, Kandel, Leonid, Safran, Ori, Dresner-Pollak, Rivka“…To investigate the role of Sirtuin1 (Sirt1), a key player in metabolism, in MAT, marrow adiposity was evaluated in inbred 5-month-old 129/Sv Sirt1 haplo-insufficient (Sirt1(Δ/+)) and wild type (WT) mice. …”
Publicado 2019
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7762por Pan, Jingwei, Yuan, Mingyuan, Yu, Mengmeng, Gao, Yajie, Shen, Chengxing, Wang, Yining, Lu, Bin, Zhang, Jiayin“…RESULTS: The mean radiation dose for dynamic CT-MPI was 3.2 ± 1.1 mSv. Infarcted territories had significantly lower MBF (30.5 ± 7.4 mL/min/100 mL versus 73.4 ± 8.1 mL/min/100 mL, p < 0.001) and myocardial blood volume (MBV) (2.8 ± 0.9 mL/100 mL versus 4.2 ± 1.1 mL/100 mL, p = 0.044) compared with those of reference territories. …”
Publicado 2019
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7763“…Our studies show an emerging role of Ca(V)β in determining SV maturation toward the priming state and its replenishment after release. …”
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7764por Koskas, Yoann, Lannes, François, Branger, Nicolas, Giusiano, Sophie, Guibert, Nicolas, Pignot, Géraldine, Walz, Jochen, Rossi, Dominique, Bastide, Cyrille“…The inclusion criteria were: follow-up > 24 months, undetectable postoperative prostate-specific antigen (PSA), no seminal vesicle (SV) invasion, no lymph node invasion confirmed by surgery (pN0) or imaging (pNx), and no neoadjuvant or adjuvant treatment. …”
Publicado 2019
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7765por Roger, Claire, Zieleskiewicz, Laurent, Demattei, Christophe, Lakhal, Karim, Piton, Gael, Louart, Benjamin, Constantin, Jean-Michel, Chabanne, Russell, Faure, Jean-Sébastien, Mahjoub, Yazine, Desmeulles, Isabelle, Quintard, Hervé, Lefrant, Jean-Yves, Muller, Laurent“…Fluid responsiveness was defined as a > 15% increase in stroke volume (SV) assessed by velocity-time integral (VTI) measurements at baseline (T(0)), at the end of FC (T(10)), then 10 (T(20)) and 20 min (T(30)) after the end of FC. …”
Publicado 2019
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7766“…Comparison with the transcriptional changes induced by systemic infection by the geminivirus Tobacco curly shoot virus (TbSV) shows common subsets of up- and down-regulated genes similarly affected by both viral species, unveiling a common transcriptional repression of terpenoid biosynthesis, a process also suppressed by the geminivirus Tomato yellow leaf curl China virus. …”
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7767por Yamamoto, Kana, Nomura, Shuhei, Tsubokura, Masaharu, Murakami, Michio, Ozaki, Akihiko, Leppold, Claire, Sawano, Toyoaki, Takita, Morihito, Kato, Shigeaki, Kanazawa, Yukio, Anbe, Hiroshi“…Based on the most conservative assumption, their maximum annual effective doses by Cs-134 and Cs-137 together were estimated at 16 µSv/year. Contrary to limited internal contamination risks and counter-dose initiatives by the government, a considerable number of pregnant women were still concerned about consuming potentially contaminated local food products when purchasing them at supermarkets between 2012 (78.4%) and 2015 (75.0%). …”
Publicado 2019
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7768“…Backcross and intercross populations generated from mating A/J(HD) males with females from four different inbred strains produced recombinant populations with highly variable rates of affected offspring, ranging from none in C57BL/6 J intercrosses, to a few mice with HD using 129S1/SvImJ intercrosses and C57BL/6 J backcrosses, but nearly 8% of intercrosses and > 17% of backcrosses from SJL/J related populations developed HD. …”
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7769“…The estimated effective dose of a rest and stress CT MPI study was 3.04 and 3.19 mSv respectively. CONCLUSION: Quantitative rest and stress myocardial perfusion measurement with a large-coverage CT scanner improves the diagnostic accuracy for detecting functionally significant coronary stenosis.…”
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7770por Bao, Bowen, Zheng, Chunlei, Yang, Bowen, Jin, Yue, Hou, Kezuo, Li, Zhi, Zheng, Xueying, Yu, Shitong, Zhang, Xiaojie, Fan, Yibo, Qu, Xiujuan, Liu, Yunpeng, Che, Xiaofang“…Furthermore, EMCN and COL4A5, rather than CCL11, were proved to be able to enhance the adhesion ability of MKN45 and NUGC4 cells to peritoneal mesothelial cell line HMR-SV5. Eventually, it was proved that COL4A5 promoted peritoneal metastasis by activating Wnt signaling pathway, whereas the upregulation of integrin family genes mediated by FAK-AKT/ERK/STAT3 signaling pathway activation is involved in peritoneal metastasis promotion function of EMCN. …”
Publicado 2019
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7771por Suseel, Appu, Panchu, Pallavi, Abraham, Siju V, Varghese, Salish, George, Tijo, Joy, Lijo“…HOW TO CITE THIS ARTICLE: Suseel A, Panchu P, Abraham SV, Varghese S, George T, Joy L. An Analysis of the Efficacy of Different Teaching Modalities in Imparting Adult Cardiopulmonary Resuscitation Skills among First-year Medical Students: A Pilot Study. …”
Publicado 2019
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7772“…MATERIALS AND METHODS: ANG II infusion was used to establish the hypertensive model in HT22 cells and 129S6/SvEvTac mice, respectively. TUNEL assay was used to evaluate the apoptosis level. …”
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7773por Valbuena, Gabriel N., Cantoni, Lavinia, Tortarolo, Massimo, Bendotti, Caterina, Keun, Hector C.“…We examined effects of SOD1(G93A) on thoracic and lumbar spinal cord metabolites in two mouse ALS models with different rates of disease progression: the transgenic SOD1(G93A)-C57BL/6JOlaHsd (C57-G93A, slow progression) and transgenic SOD1(G93A)-129SvHsd (129S-G93A, fast progression) strains. Samples from three timepoints (presymptomatic, disease onset, and late stage disease) were analyzed using Gas Chromatography-Mass Spectrometry metabolomics. …”
Publicado 2019
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7774por Kollmus, Heike, Fuchs, Helmut, Lengger, Christoph, Haselimashhadi, Hamed, Bogue, Molly A., Östereicher, Manuela A., Horsch, Marion, Adler, Thure, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, Beckers, Johannes, Calzada-Wack, Julia, Garrett, Lillian, Hans, Wolfgang, Hölter, Sabine M., Klein-Rodewald, Tanja, Maier, Holger, Mayer-Kuckuk, Philipp, Miller, Gregor, Moreth, Kristin, Neff, Frauke, Rathkolb, Birgit, Rácz, Ildikó, Rozman, Jan, Spielmann, Nadine, Treise, Irina, Busch, Dirk, Graw, Jochen, Klopstock, Thomas, Wolf, Eckhard, Wurst, Wolfgang, Yildirim, Ali Önder, Mason, Jeremy, Torres, Arturo, Balling, Rudi, Mehaan, Terry, Gailus-Durner, Valerie, Schughart, Klaus, Hrabě de Angelis, Martin“…The collaborative cross (CC) is a large panel of mouse-inbred lines derived from eight founder strains (NOD/ShiLtJ, NZO/HILtJ, A/J, C57BL/6J, 129S1/SvImJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ). Here, we performed a comprehensive and comparative phenotyping screening to identify phenotypic differences and similarities between the eight founder strains. …”
Publicado 2020
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7775por Zhang, Jianping, Zhang, Jiangang, Xu, Xiaoping, Lu, Linjun, Hu, Silong, Liu, Chang, Cheng, Jingyi, Song, Shaoli, Zhang, Yingjian, Shi, L. Q.“…The total-body absorbed dose was 1.54E-03 ± 2.43E-04 mGy/MBq, and the effective dose was 3.72E-03 ± 4.5E-04 mSv/MBq. Compared to published studies of other similar PSMA tracers and (99m)Tc-targeted conventional tracers, the absorbed doses of (99m)Tc-HYNIC-PSMA in all organs showed that it could be used safely in the human body. …”
Publicado 2020
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7776por An, Bingxing, Xu, Lei, Xia, Jiangwei, Wang, Xiaoqiao, Miao, Jian, Chang, Tianpeng, Song, Meihua, Ni, Junqing, Xu, Lingyang, Zhang, Lupei, Li, Junya, Gao, Huijiang“…Among these, 21 genes were promising candidate genes, including SOX2, SNRPD1, RASGEF1B, EFNA5, PTBP1, SNX9, SV2C, PKDCC, SYNDIG1, AKR1E2, and PRIM2 identified by single-trait analysis; SLC37A1, LAP3, PCDH7, MANEA, and LHCGR identified by multi-trait analysis; and P2RY1, MPZL1, LINGO2, CMIP, and WSCD1 identified by LONG-GWAS. …”
Publicado 2020
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7777“…All specimens were inoculated onto R-mix™ shell vials (SV) and CC tubes; and a subset also underwent DAT for influenza A and B and/or RSV. …”
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7778“…In addition, qRT-PCR and Western blotting were applied to detect the expression levels of GRHL2 and ZEB1 in bladder cancer cell lines (RT4, BIU-87, 5637, T24) and immortalized human bladder epithelial cell line (SV-HUC-1). The cell models with up-regulated and down-regulated expression of GRHL2 were constructed using bladder cancer cell lines T24 and 5637 to investigate the underlying roles of GRHL2 on the proliferation, migration, invasion and EMT process of bladder cancer cells. …”
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7779por Treskes, Kaij, Saltzherr, Teun P., Edwards, Michael J. R., Beuker, Benn J. A., Van Lieshout, Esther M. M., Hohmann, Joachim, Luitse, Jan S. K., Beenen, Ludo F. M., Hollmann, Markus W., Dijkgraaf, Marcel G. W., Goslings, J. Carel“…The revised set retains 8.78 mSv (95% CI 6.01–11.56) for 36% of the non-severely injured patients. …”
Publicado 2020
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7780por Deng, Mingyan“…All participants underwent cardiac magnetic resonance examinations and recorded their cardiac structure, functional indicators (such as ejection fraction (EF), end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume(SV), peak filling rate (PFR),myocardial perfusion index (maximum upslope (Slope), half time to maximum signal intensity (Time50Max (s)), time to maximum signal intensity (TimeMax (s)), the maximum signal intensity (MaxSI),, basic signal intensity (Baseline),the ratio of MaxSI and Baseline ((MaxSI (BL) %), the difference value between MaxSI and Baseline (MaxSI (BL))). …”
Publicado 2020
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