“…Most AEs were low-grade, although 19.21% of AEs were common terminology criteria for adverse events (CTCAE) Grades 3 or 4. …”
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“…The solids of the BB and CB contained protein (16.88–19.21%), fat (0.01–0.23%), ash (12.89–13.50%), carbohydrate (67.28–70.00%), sugars and polyols (40.55–45.68%), free amino acids (6.58–6.69%), 5′-nucleotides (0.98–1.47%), and bioactive components, especially polysaccharides (4.53–7.45%), ergothioneine (both 0.19%), and total phenols (0.15–0.36%). …”
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“…TNF-alpha has been shown to antagonize the proliferative effects of growth factors present in crude conditioned media from PHA-stimulated leukocytes or cell lines on the clonogenic cells of acute myeloblastic leukemia (AML) (19,21). In the present study, we investigated the responses of AML blasts to TNF-alpha in the presence of defined growth factors (recombinant granulocyte/macrophage-CSF [rGM-CSF], recombinant granulocyte-CSF [rG-CSF], rIL-3, and rIL-1) and under conditions described for autocrine stimulation (32). …”
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“…STUDY POPULATION: Women participating in the Australian Longitudinal Study on Women’s Health (ALSWH), born 1921–1926 and 1946–1951, and two cohorts of British women, the British Women’s Heart and Health Study and the MRC National Survey of Health and Development, born at similar times (1920 to 1939 and 1946, respectively) and surveyed at similar ages to the ALSWH cohorts. …”
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“…The term “robot” was coined by the Czech playright Karel Capek in 1921 in his play Rossom's Universal Robots. The word “robot” is from the check word robota which means forced labor. …”
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“…The three conserved pseudouridine modifications (Ψ1911, Ψ1915, Ψ1917) occurring in the loop of the E. coli H69 affected the dissociation constant, but not the stoichiometry for the binding of paromomycin (K(d) = 2.6 ± 0.1 µM). G1906 and G1921, observed by NMR spectrometry, figured predominantly in the aminoglycoside binding to H69. …”
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“…METHODS: The authors used data from the 1921-26 cohort (n = 12,416, aged 70-75 in 1996) of the Australian Longitudinal Study on Women's Health (ALSWH). …”
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“…RESULTS: With the use of different references the prevalence of thinness varies from 17.18% to 27.73% among the boys and from 19.21% to 28.23% among the girls. On the other hand the prevalence of overweight varies from 1.95% to 7.81% among the boys and 1.96% to 9.41% among the girls. …”
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“…Exome array data were obtained in the Lothian Birth Cohorts of 1921 and 1936 (combined N = 1596). General cognitive ability was assessed at age 11 years and in late life (79 and 70 years, respectively) and was modelled against the total number of stop-gain/loss, splice, and missense exonic variants, with minor allele frequency less than or equal to 0.01, using linear regression adjusted for age and sex. …”
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“…Powers, MD, was one of the most influential figures in American Pediatrics and certainly the leader who created the modern Department of Pediatrics at Yale when he was recruited in 1921 from Johns Hopkins and then served as its second chairman from 1927 to 1951. …”
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“…A physical–empirical model that captures these new predictors can produce an independent forecast skill of 0.51 for 1989–2012 and a 92-year retrospective forecast skill of 0.64 for 1921–2012. The recent low skills of the dynamical models are attributed to deficiencies in capturing the developing CP–ENSO and anomalous Asian Low. …”
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“…All available data about centipedes in Slovenia collected from 1921 to 2014 have been consolidated and constitute a general electronic database called “CHILOBIO”, which was created to provide an easy overview of the Slovenian centipede fauna and to allow entry and interpretation of new data collected in future research. …”
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“…Two northeast Brazilian samples were used: a cross-sectional sample of 3659 (1921 girls) aged 8 to 16 years and a mixed-longitudinal series of cohorts (8–10, 10–12, 12–14, 14–16 years) with 250 boys and 250 girls. …”
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“…Using a 99-CpG aging model, a five-year higher age-prediction was associated with 11% greater mortality risk in DNAm profiles of the Lothian Birth Cohort 1921 study. However, models based on three CpGs, or even individual CpGs, generally revealed very high offsets in age-predictions if applied to independent microarray datasets. …”
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“…Although the attenuated Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine has been used since 1921, tuberculosis (TB) control still proceeds at a slow pace. …”
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“…RESULTS: In comparison with the control group, the passive smoking group showed a significant increase in mast cell degranulation (19.75 ± 3.77% vs. 42.53 ± 0.42%; p < 0.001) and in the levels of reduced glutathione (293.9 ± 19.21 vs. 723.7 ± 67.43 nM/g of tissue; p < 0.05); as well as a significant reduction in mucociliary clearance (p < 0.05), which caused significant changes in pulmonary function (in MIP and MEP; p < 0.05 for both) and airway hyperreactivity. …”
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