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  1. 71401
    “…In the current study, a random transposon (Tn) insertion library was constructed in L. monocytogenes strain F2365 and screened to identify genes and pathways affecting in vitro growth and fitness in minimal medium (MM) containing different single carbohydrate as the sole carbon source. About 2,000 Tn-mutants were screened for impaired growth in MM with one of the following carbon sources: glucose, fructose, mannose, mannitol, sucrose, glycerol, and glucose 6-phosphate (G6P). …”
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    Identification of genetic elements required for Listeria monocytogenes growth under limited nutrient conditions and virulence by a screening of transposon insertion library
  2. 71402
    “…METHOD: We searched the PubMed, Cochrane Library, Web of Science, Medline and Embase covering January 1, 2000 to April 30, 2022. Randomized control trials comparing finerenone or SGLT2i with placebo in patients with T2DM and CKD were selected. …”
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    Network meta-analysis on the efficacy and safety of finerenone versus SGLT2 inhibitors on reducing new-onset of atrial fibrillation in patients with type 2 diabetes mellitus and chronic kidney disease
  3. 71403
    “…We matched total of 5439 5-year solid CCS diagnosed before the age of 21 between 1945 and 2000 by sex, birth year and region of residence to 386,073 individuals of the French general population. …”
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    Long-term hospitalisations in survivors of paediatric solid tumours in France
  4. 71404
    “…METHODS: We used the Canadian Community Health Survey from 2000 to 2016 to create a large population-representative cohort of individuals over the age of 30 and free from prior stroke. …”
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    Vascular risk factors and stroke risk across the life span: A population-representative study of half a million people
  5. 71405
    “…Following PRISMA guidelines, we identified studies published between January 2000 and March 2022 from online databases. Search keywords included EEG, addictive substances (e.g., alcohol, cocaine, methamphetamine), and treatment related terms (e.g., abstinence, relapse). …”
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    A scoping review of electroencephalographic (EEG) markers for tracking neurophysiological changes and predicting outcomes in substance use disorder treatment
  6. 71406
    “…The primary event was time-to-COPD diagnosis during the follow-up period (January 1, 2000 to December 31, 2018). The proportion of days covered (PDC) – was used as a surrogate measure for medication adherence (MA) assessed at optimal-level (≥ 0.80), Intermediate-level (0.50–0.79), and low-level (< 0.5) of adherence. …”
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    Association Between Medication Adherence and Risk of COPD in Adult Asthma Patients: A Retrospective Cohort Study in Canada
  7. 71407
    “…Data were collected (in 2014 and 2015) through a survey of 97 Canadian dairy herds that shifted to AMS from 2000 to 2014. Producers were asked their perception about milk yield and SCC changes (increase, decrease, or no change) after AMS introduction. …”
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    Performance perception of Canadian dairy producers when transitioning to an automatic milking system
  8. 71408
    “…After washing and addition of read buffer, the signal responses are measured in a SQ120 reader and concentration in test samples is estimated by dose-interpolation using a weighted 5-PL curve fit with an EFX standard curve ranging from 10–2,000 ng/mL. The new assay allows measurement of serum EFX at concentrations as low at 20 ng/mL. …”
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    ODP178 Development and Validation of a Noncompetitive Immunoassay Optimized for the Assessment of Pharmacokinetics of Biologically Active Efruxifermin in Humans
  9. 71409
    por Boily, Pascale, St-Jean, Matthieu
    Publicado 2022
    “…Adults followed at CHUS between 2000 and 2021, with a confirmed diagnosis of PA and a follow-up of at least 6 months were included. …”
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    ODP038 Efficacy of Medical Treatment Compared to Unilateral Adrenalectomy in a Cohort of Patients with Primary Aldosteronism Treated at the Centre Hospitalier Universitaire de Sherbrooke – CHUS
  10. 71410
    “…BACKGROUND: The Accelerating Innovation for Mothers (AIM) project established a database of candidate medicines in research and development (R&D) between 2000 and 2021 for five pregnancy-related conditions, including pre-eclampsia. …”
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    Systematic evaluation of the pre-eclampsia drugs, dietary supplements and biologicals pipeline using target product profiles
  11. 71411
    por Lyu, Qian, Nie, Yu, Yuan, Jiazheng, Wang, Dong
    Publicado 2022
    “…Therefore, the study used a population-based cohort study in the United States from 2000 to 2017 to analyze causes of death for women who underwent local tumor excision or radical cystectomy stratified by demographics and tumor stage. standardized mortality ratios (SMRs) were calculated based on general population data. …”
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    Causes of death in female patients with bladder cancer after local tumor excision and radical cystectomy: a contemporary, US population-based analysis
  12. 71412
    “…Specimens and clinicopathological data of 642 GBC patients, diagnosed between 2000 and 2019 were collected using the Dutch Pathology Registry (PALGA) and the Netherlands Cancer Registry. …”
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    Comprehensive clinicopathological and genomic profiling of gallbladder cancer reveals actionable targets in half of patients
  13. 71413
    “…METHODS: We conducted a review of football players who underwent shoulder labral repair between 2000 and 2020 at a single institution. Inclusion criteria were NCAA Division I level, diagnosis of shoulder instability, and labral tear requiring arthroscopic repair. …”
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    Player Position and Labral Tear Location and Size in NCAA Division I Football Players Undergoing Arthroscopic Surgery
  14. 71414
    “…METHODS: The clinical data of patients with RCC and VTT diagnosed from 2000–2018 in the Surveillance Epidemiology and End Results (SEER) database were downloaded and compared with the clinical data of patients with VTT admitted to the Department of Urology of the Tongji Hospital (TJH) from 2004–2020. …”
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    Prognostic indicators for survival in renal cell carcinoma with venous thrombus and development of predictive nomograms
  15. 71415
    “…Patients with CMP diagnosed between 2000 and 2017 were assigned to the case group; patients without CMP were randomly selected from the same database and paired with controls matched by age and sex. …”
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    Chondromalacia patella increases the risk of herpes zoster: a population-based study
  16. 71416
    “…Searches were limited to English-language items published from 1 January 2000 to 14 June 2022. No publication-type limit was used. …”
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    Interventions to support the mental health and well-being of front-line healthcare workers in hospitals during pandemics: an evidence review and synthesis
  17. 71417
    “…Included studies were published between 2000 and 2020 reporting on the attributes, evidence usage and impact of clinical practice guidelines and clinical quality registries on health service delivery. …”
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    Which strategies support the effective use of clinical practice guidelines and clinical quality registry data to inform health service delivery? A systematic review
  18. 71418
    por Dong, Zheng, Zhou, Hongyu
    Publicado 2022
    “…Here, we performed a pan-cancer analysis of genome-wide DNAm in over 2,000 samples from nine pediatric cancers to elucidate the DNAm landscape of pediatric cancers. …”
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    Pan-cancer landscape of aberrant DNA Methylation across childhood Cancers: Molecular Characteristics and Clinical relevance
  19. 71419
    por Rabiei, Reza, Almasi, Sohrab
    Publicado 2022
    “…METHODS: In this systematic review, four databases, including the Web of Science, PubMed, EMBASE, and Scopus, were searched to find relevant articles from 2000 until May 30, 2020. The final search was conducted on May 30, 2020. …”
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    Requirements and challenges of hospital dashboards: a systematic literature review
  20. 71420
    “…METHODS: A retrospective multicenter analysis of patients treated for AciCC of the parotid gland from 2000 to 2021 was performed. Exclusion criteria were pediatric (0–18 years) patients, the absence of follow-up and patients with secondary metastatic disease to the parotid gland. …”
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    Acinic cell carcinoma of the parotid gland: Timeo Danaos et dona ferentes? A multicenter retrospective analysis focusing on survival outcome
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