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71621por Gibson, Angela, Joe, Victor, Carson, Joshua, Litt, Jeff, Carter, Jeffrey, Holmes, James“…A single application of up to 1:1 meshed BACC was applied to ≤3 burn areas on the torso or extremities (≤2000 cm(2) area of BACC). Patients were followed for 24 weeks. …”
Publicado 2023
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71622“…METHODS: The clinical factors and survival outcomes of SMPCC patients registered on the Surveillance, Epidemiology, and End Results (SEER) database between 2000 and 2017 were extracted. The patients were divided into the training and validation cohorts using a ratio of 7:3. …”
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71623por Chou, Chu-Lin, Chung, Chi-Hsiang, Hsu, Yung-Ho, Wu, Chia-Chao, Sun, Chien-An, Chien, Wu-Chien, Tang, Shih-En, Fann, Li-Yun“…This study analyzed data from the National Health Insurance Research Database from January 2000 to December 2015. Overall, 136,211 individuals diagnosed with chronic stroke who suffered from acute TBI and received inpatient service were enrolled. …”
Publicado 2023
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71624por Kamble, Suchit, Shidhaye, Pallavi, Mukherjee, Anupam, Tak, Madhuri, Bembalkar, Shilpa, Aggarwal, Sumit, Deb, Arpita, Kapoor, Neha, Verma, Vinita, Das, Chinmoyee, Kulkarni, Smita, Ghate, Manisha, Godbole, Sheela“…HIV-1 VL testing using Abbott m2000 platform and DBS as a sample type. METHODS: This ethically approved feasibility study will be implemented at two moderate to high burden ART centres where VL testing facility is not available in the town. …”
Publicado 2023
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71625por Gu, Yu, Wang, Dan, Jia, Congwei, Chen, Lihua, Cang, Wei, Wan, Xirun, Yang, Junjun, Xiang, Yang“…MATERIAL AND METHODS: Seventy recurrent adult granulosa cell tumor patients treated in Peking Union Medical College Hospital between 2000 and 2020 were retrospectively reviewed. The primary outcomes were progression‐free survival after first recurrence (PFS‐R), overall survival after first recurrence (OS‐R) and recurrence frequency. …”
Publicado 2023
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71626por Sarti, Aimee J., Honarmand, Kimia, Sutherland, Stephanie, Hornby, Laura, Wilson, Lindsay C., Priestap, Fran, Carignan, Robert, Joanne, Brennan, Brewster, Heather, Elliott-Pohl, Kennedy, Weiss, Matthew, Shemie, Sam D.“…Survey questions evaluated understanding of how death is determined, acceptance of death determination by neurologic and circulatory criteria, and interest and preferred strategies in learning more about the topic. RESULTS: Among 2,000 respondents (50.8% women; n = 1,015), nearly 67.2% believed that the man in scenario 1 was dead (n = 1,344) and 81.2% (n = 1,623) believed that the man in scenario 2 was dead. …”
Publicado 2023
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71627por Adam, Claire E., Fitzpatrick, Annette L., Leary, Cindy S., Hajat, Anjum, Ilango, Sindana D., Park, Christina, Phelan, Elizabeth A., Semmens, Erin O.“…METHODS: Falls were self-reported every six months, and gait speed was ascertained annually among 2,776 participants in the Ginkgo Evaluation of Memory Study (2000–2008). Adjusted Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for fall risk relative to a 12-month change in gait speed. …”
Publicado 2023
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71628“…CONCLUSIONS AND RELEVANCE: This cohort study demonstrated that the $2000 out-of-pocket cap included in the Inflation Reduction Act may substantially moderate the potential increase in spending faced by individuals who use ultra-expensive drugs when moving from commercial insurance to Part D coverage.…”
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71629“…For the quantification of flow velocity of mLVs, IR-ALADDIN was performed at three inversion times of 2000, 2300, and 2600 ms (three-TI IR-ALADDIN) for both a flow phantom and humans. …”
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71630por Kastlmeier, Miriam T., Gonzalez-Rodriguez, Erika, Cabanis, Phoebe, Guenther, Eva M., König, Ann-Christine, Han, Lianyong, Hauck, Stefanie M., See, Fenja, Asgharpour, Sara, Bukas, Christina, Burgstaller, Gerald, Piraud, Marie, Lehmann, Mareike, Hatz, Rudolf A., Behr, Jürgen, Stoeger, Tobias, Hilgendorff, Anne, Voss, Carola“…To screen for key mediators of the misguided mesenchymal-to-epithelial crosstalk with a focus on disease-relevant inflammatory processes, we used mass spectrometry and characterized the secretome of end stage fibrotic-ILD lung fibroblasts in comparison to non-chronic lung disease (CLD) patient fibroblasts. Out of the over 2000 proteins detected by this experimental approach, 47 proteins were differentially abundant comparing fibrotic-ILD and non-CLD fibroblast secretome. …”
Publicado 2023
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71631por Zhang, Lu, Dong, Yu-jun, Peng, Hong-ling, Li, Hao, Zhang, Ming-zhi, Wang, Hui-han, Liu, Qin-hua, Su, Li-ping, Zhong, Li-ye, Wu, Wen-jun, Huang, Liang, Yan, Xiao-jing, Fan, Lei, Tang, Wen-jiao, Li, Zhen-ling, Bi, Lin-tao, Li, Yan, Gao, Guang-xun, Gao, Li, Liu, Ting-bo, Wei, Yong-qiang, Liu, Yao, Yu, Li, Zhou, Hui, Sun, Chun-yan, Qian, Wen-bin, Zou, De-hui, Zhang, Hui-lai, Ding, Kai-yang, Wang, Xiao-bo, Bai, Ou, Huang, Wen-rong, Chen, Bing, Yang, Lin, Song, Jia, Gao, Da, Chen, Tong, Luo, Jun, Wang, Shu-ye, Ma, Liang-ming, Fajgenbaum, David C., Li, Jian“…METHODS: In this national, multicenter, retrospective study implementing CDCN criteria, we enrolled 1634 CD patients (UCD, n = 903; MCD, n = 731) from 2000 to 2021 at 40 Chinese institutions to depict clinical features, treatment options, and prognostic factors of CD. …”
Publicado 2023
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71632por Yoon, Wan-Soo, Chang, Jong Hee, Kim, Jeong Hoon, Kim, Yu Jung, Jung, Tae-Young, Yoo, Heon, Kim, Se-Hyuk, Ko, Young-Cho, Nam, Do-Hyun, Kim, Tae Min, Kim, Se Hoon, Park, Sung-Hae, Lee, Youn Soo, Yim, Hyeon Woo, Hong, Yong-Kil, Yang, Seung Ho“…METHODS: Included patients were randomly assigned to a control group [placebo plus low-dose temozolomide (50 mg/m(2), daily)] or an experimental group [metformin (1000 mg, 1500 mg, and 2000 mg per day during the 1st, 2nd, and 3rd week until disease progression, respectively) plus low-dose temozolomide]. …”
Publicado 2023
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71633por Lourenção, Marina, Arruda, Gustavo Viani, Rocha, Lucas Penna, Galendi, Julia Simões Corrêa, de Oliveira, Jorge Caldeira, Jacinto, Alexandre Arthur“…For the probabilistic sensitivity analysis, the cost-effectiveness acceptability curve indicates that there is a probability of 99.99% of HYPOFRT being cost-effective considering a willingness-to-pay threshold of R$2,000 ($905.39) per QALY (public sector) and willingness-to-pay threshold of R$16,000 ($7243.10) per QALY (private sector). …”
Publicado 2023
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71634por Osdaghi, Ebrahim, Robertson, Alison E., Jackson‐Ziems, Tamra A., Abachi, Hamid, Li, Xiang, Harveson, Robert M.“…After an outbreak during the 1970s, prevalence of the disease decreased in the 1980s to the early 2000s, before the disease resurged causing a serious threat to maize production in North America. …”
Publicado 2022
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71635“…During CAR-T cell therapy in 35 patients with ALL, fever accounted for 62.86%, chills for 20.00%, gastrointestinal bleeding for 8.57%, nervous system symptoms for 14.29%, digestive system symptoms for 28.57%, abnormal liver function for 11.43%, and coagulation dysfunction for 8.57%. …”
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71636“…METHODS: We searched the PubMed, Embase, and Cochrane Library of Systematic Reviews databases from January 2000 to July 2022 to identify studies that, evaluated the efficacy and safety of mTLT in glaucoma. …”
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71637“…METHODS: We searched PubMed, EMBASE, Web of Science, and the Cochrane Central Register of Controlled Trials from January 2000 until April 2022. RCTs directly comparing regional and general anesthesia in hip fracture surgery were included in the analysis. …”
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71638por Tzanetakos, Dimitrios, Kyrozis, Andreas, Karavasilis, Efstratios, Velonakis, Georgios, Tzartos, John S., Toulas, Panagiotis, Sotirli, Stefania Alexia, Evdokimidis, Ioannis, Tsivgoulis, Georgios, Potagas, Constantin, Kilidireas, Costantinos, Andreadou, Elisabeth“…Data from 35 patients with CIS (CIS group), of which 23 were untreated (CIS-untreated group) and 12 were treated (CIS-treated group) with disease-modifying-therapies (DMTs) at the time of (1)H-MRS, and from 28 age- and sex-matched HCs were collected using a 3.0 T MRI and single-voxel (1)H-MRS (point resolved spectroscopy sequence; repetition time, 2,000 msec; time to echo, 35 msec). Concentrations and ratios of total N-acetyl aspartate (tNAA), total creatine (tCr), total choline (tCho), myoinositol, glutamate (Glu), glutamine (Gln), Glu + Gln (Glx) and glutathione (Glth) were estimated in the thalamic-voxel (th) and centrum semiovale-voxel (cs). …”
Publicado 2023
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71639por Crespo, Grace Velez, Ortiz, Jescelica, O’Farrill, Eliud Hernández, Vlaar, Cornelis P., Inyushin, Mikhail, Kucheryavykh, Yuriy, Kucheryavykh, Lilia“…RESULTS: HV-107 inhibited Rac activity by 50% in MDA-MB-231 and MDA-MB-468 cells at concentrations of 250–2000 nM, leading to a 90% decrease in invasion and invadopodia activity. …”
Publicado 2023
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71640por Geoffrois, Lionnel, Harlé, Alexandre, Sahki, Nassim, Sikanja, Aleksandra, Granel-Brocard, Florence, Hervieu, Alice, Mortier, Laurent, Jeudy, Géraldine, Michel, Catherine, Nardin, Charlée, Huin-Schohn, Cécile, Merlin, Jean-Louis“…BACKGROUND: With more than 15,000 new cases /year in France and 2,000 deaths, cutaneous melanoma represents approximately 4% of incidental cancers and 1.2% of cancer related deaths. …”
Publicado 2023
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