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  1. 71821
    “…In 1995, 7,900 people died from AIDS in the country; and the annual number rose to 25,000 in 2000. Out of 1,200,000 orphans and vulnerable children in Cameroon in 2010, 300,000(25%) were AIDS orphans. …”
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    The Burden of Orphans and Vulnerable Children Due to HIV/AIDS in Cameroon
  2. 71822
    por Elbers, Clara C., Guo, Yiran, Tragante, Vinicius, van Iperen, Erik P. A., Lanktree, Matthew B., Castillo, Berta Almoguera, Chen, Fang, Yanek, Lisa R., Wojczynski, Mary K., Li, Yun R., Ferwerda, Bart, Ballantyne, Christie M., Buxbaum, Sarah G., Chen, Yii-Der Ida, Chen, Wei-Min, Cupples, L. Adrienne, Cushman, Mary, Duan, Yanan, Duggan, David, Evans, Michele K., Fernandes, Jyotika K., Fornage, Myriam, Garcia, Melissa, Garvey, W. Timothy, Glazer, Nicole, Gomez, Felicia, Harris, Tamara B., Halder, Indrani, Howard, Virginia J., Keller, Margaux F., Kamboh, M. Ilyas, Kooperberg, Charles, Kritchevsky, Stephen B., LaCroix, Andrea, Liu, Kiang, Liu, Yongmei, Musunuru, Kiran, Newman, Anne B., Onland-Moret, N. Charlotte, Ordovas, Jose, Peter, Inga, Post, Wendy, Redline, Susan, Reis, Steven E., Saxena, Richa, Schreiner, Pamela J., Volcik, Kelly A., Wang, Xingbin, Yusuf, Salim, Zonderland, Alan B., Anand, Sonia S., Becker, Diane M., Psaty, Bruce, Rader, Daniel J., Reiner, Alex P., Rich, Stephen S., Rotter, Jerome I., Sale, Michèle M., Tsai, Michael Y., Borecki, Ingrid B., Hegele, Robert A., Kathiresan, Sekar, Nalls, Michael A., Taylor, Herman A., Hakonarson, Hakon, Sivapalaratnam, Suthesh, Asselbergs, Folkert W., Drenos, Fotios, Wilson, James G., Keating, Brendan J.
    Publicado 2012
    “…To address this, we performed dense genotyping of ∼2,000 candidate genes in 7,657 African Americans, 1,315 Hispanics and 841 East Asians, using the IBC array, a custom ∼50,000 SNP genotyping array. …”
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    Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations
  3. 71823
    “…Exome analysis was performed using the Agilent SureSelect 50Mb All Exon Kit and the Illumina HiSeq 2000 next-generation-sequencing (NGS) platform. Compound heterozygous mutations were identified by exome sequencing and confirmed by Sanger sequencing within the dehydrogenase domain (c.101C>T; p.Ala34Val) and hydratase domain (c.1547T>C; p.Ile516Thr) of the 17β-hydroxysteroid dehydrogenase type 4 gene (HSD17B4). …”
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    Specific combination of compound heterozygous mutations in 17β-hydroxysteroid dehydrogenase type 4 (HSD17B4) defines a new subtype of D-bifunctional protein deficiency
  4. 71824
    “…The patients underwent CCRT between 2000 and 2010. The mean patient age was 68.1 years (range, 46-80 years). …”
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    Correlation among 16 biological factors [p53, p21(waf1), MIB-1 (Ki-67), p16(INK4A), cyclin D1, E-cadherin, Bcl-2, TNF-α, NF-κB, TGF-β, MMP-7, COX-2, EGFR, HER2/neu, ER, and HIF-1α] and clinical outcomes following curative chemoradiation therapy in 10 patients with esophageal squamous cell carcinoma
  5. 71825
    “…RESULTS: The overall transcriptome analysis of TGFβ3 wildtype mice (C57BL/6) reveals that almost 6000 genes were upregulated during the transition from E14.5 to E15.5 and more than 2000 were downregulated from E15.5 to E16.5. Using bioinformatics tools and databases, we identified the most comprehensive list of CP genes (n = 322) in which mutations cause CP either in humans or mice, and analyzed their expression patterns. …”
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    Systematic analysis of palatal transcriptome to identify cleft palate genes within TGFβ3-knockout mice alleles: RNA-Seq analysis of TGFβ3 Mice
  6. 71826
    “…METHODS: We searched databases and systematic review citations for papers published between 2000 and 2012 (May) that evaluated the perceived impact of using an EMR system in an office-based practice, were based on original data, had providers as the primary end user, and reported outcome measures related to the system’s positive or negative impact. …”
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    Perceived Impact of Electronic Medical Records in Physician Office Practices: A Review of Survey-Based Research
  7. 71827
    “…METHODS: From January 2000 to December 2006, 101 newly diagnosed elderly non-metastatic NPC patients (age≥65 years) who received cisplatin 3-weekly or weekly concurrent CRT with/without sequential chemotherapy were recruited. …”
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    Feasibility and efficacy of chemoradiotherapy for elderly patients with locoregionally advanced nasopharyngeal carcinoma: results from a matched cohort analysis
  8. 71828
    “…We morphologically identified 72 Anopheles gambiae sl. from 156 mosquitoes captured by pyrethrum spray catches in sleeping rooms of households within a 2,000 km(2) vicinity of the Malaria Institute at Macha. …”
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    A Simple Chelex Protocol for DNA Extraction from Anopheles spp.
  9. 71829
    “…METHODS: The Systemic Lupus International Collaborating Clinics Registry for Atherosclerosis inception cohort enrolled recently diagnosed (<15 months) SLE patients from 30 centres across 11 countries from 2000. Clinical, laboratory and therapeutic data were collected according to a standardised protocol. …”
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    Clinical associations of the metabolic syndrome in systemic lupus erythematosus: data from an international inception cohort
  10. 71830
    “…METHODS: This retrospective cohort study extracted data from May 1, 2000 until June 30, 2010, from the i3 InVision Data Mart™ database. …”
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    Comparing Pioglitazone to Insulin with Respect to Cancer, Cardiovascular and Bone Fracture Endpoints, Using Propensity Score Weights
  11. 71831
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    Psychometric properties of a culture-adapted Spanish version of AIDA (Assessment of Identity Development in Adolescence) in Mexico
  12. 71832
    “…A total of 84,942 patients were registered from 2000 to 2012, growing by 10% annually. RESULTS: The SNDR reporting system for epidemiology data gives better understanding of the disease pattern, types, and gender characteristics. …”
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    A Web-Based Interactive Diabetes Registry for Health Care Management and Planning in Saudi Arabia
  13. 71833
    “…OBJECTIVE: Totally endoscopic surgery compared with the conventional heart operation in children is described in this article to find a preferable treatment for congenital heart diseases. METHODS: Between May 2000 and December 2007, 708 children with congenital heart disease were divided into two groups: endoscopic group and conventional group. …”
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    Totally endoscopic congenital heart surgery compared with the traditional heart operation in children
  14. 71834
    “…The samples were labelled with cyanine-3 (cye-3) CTP dye and the universal human reference was labelled with cyanine-5 (cye-5) CTP dye. cRNA was purified with the RNeasy Plus Mini kit and quantified using a NanoDrop 2000c spectrophotometer. The arrays were scanned data analysed using Feature Extraction and GeneSpring software. …”
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    Thymoquinone regulates gene expression levels in the estrogen metabolic and interferon pathways in MCF7 breast cancer cells
  15. 71835
    “…Since 2000, a sentinel surveillance of influenza, INFLUNET, exists in Italy. …”
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    Influenza epidemiology in Italy two years after the 2009–2010 pandemic: Need to improve vaccination coverage
  16. 71836
    “…Each individual was captured with the Agilent SureSelect Human All Exon kit, sequenced on the Illumina Hiseq 2000, and the resulting data processed and annotated with Burrows-Wheeler Aligner (BWA), Genome Analysis Toolkit (GATK), and SeattleSeq. …”
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    Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disorders
  17. 71837
    “…Associations between daily PM(2.5) constituents and sources and risk of cardiovascular and respiratory hospitalizations for the Medicare population (> 333,000 persons ≥ 65 years of age) were estimated with time-series analyses (August 2000–February 2004). Results: PM(2.5) total mass and PM(2.5) road dust contribution were associated with cardiovascular hospitalizations, as were the PM(2.5) constituents calcium, black carbon, vanadium, and zinc. …”
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    Associations of PM(2.5) Constituents and Sources with Hospital Admissions: Analysis of Four Counties in Connecticut and Massachusetts (USA) for Persons ≥ 65 Years of Age
  18. 71838
    “…Adding Covey's notion of Holistic Renewal, we held leaders accountable for self-renewal and work regeneration. In 2000, we introduced the Hartman Value Profile. This tool assesses one's value system, measuring critical-thinking skills, morale, and amount of stress. …”
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    Aligning Heart Intelligence for Strategic Impact
  19. 71839
    “…METHODS: We included 2,245 invasive tumors (1,297 screening-detected and 948 interval cancers) diagnosed from 2000 to 2009 among 645,764 women aged 45 to 69 who underwent biennial screening in Spain. …”
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    Tumor phenotype and breast density in distinct categories of interval cancer: results of population-based mammography screening in Spain
  20. 71840
    “…MATERIAL AND METHODOLOGY: Retrospectively we analyzed patients with CCHD and protein-losing enteropathy in our institution, starting from January 2000 to December 2012. The including criteria were age between two and 17 years, to have a complex congenital heart disease and available complete documentation of cardiac surgery under cardiopulmonary bypass. …”
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    Treatment of Children with Protein – Losing Enteropathy After Fontan and Other Complex Congenital Heart Disease Procedures in Condition with Limited Human and Technical Resources
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