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72081“…We did so for two time periods: the “historical” period (1971–2000), and the “projected” period (2041–2070), by county. …”
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72082por Kweon, SoonHo, Phan, Minh-Trang Thi, Chun, Sejong, Yu, HongBi, Kim, Jinho, Kim, Seokho, Lee, Jaemin, Ali, Alaa Kassim, Lee, Seung-Hwan, Kim, Sang-Ki, Doh, Junsang, Cho, Duck“…Results: The culture of NK cells with K562-OX40L cells in combination with the transient exposure to IL-21 highly enhanced NK cell expansion to approximately 2,000-fold after 4 weeks of culture, compared to a 303-fold expansion using the conventional K562 cells. …”
Publicado 2019
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72083por Vatandoust, Sina, Bright, Tim, Roy, Amitesh Chandra, Watson, David, Gan, Susan, Bull, Jeff, Abbas, Muhammad Nazim, Karapetis, Christos Stelios“…This study will be conducted according to the Note for Guidance on Good Clinical Practice (CPMP/ICH/135/95) annotated with TGA comments (Therapeutic Goods Administration DSEB July 2000) and in compliance with applicable laws and regulations. …”
Publicado 2019
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72084por Laopaiboon, Malinee, Lumbiganon, Pisake, Rattanakanokchai, Siwanon, Chaiwong, Warut, Souza, João Paulo, Vogel, Joshua P., Mori, Rintaro, Gülmezoglu, Ahmet Metin“…For Africa, Asia and Latin America, the 95% CI lower limit aORs of at least 2.0 were observed when birthweight was lower than 2200 g (aOR 3.6 (95% CI; 2.0, 6.5) of 2100–2199 g), 2100 g (aOR 7.4 (95% CI; 5.1, 10.7) of 2000–2099 g) and 2200 g (aOR 6.1 (95% CI; 3.4, 10.9) of 2100–2199 g) respectively. …”
Publicado 2019
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72085por Mwanga, Emmanuel P., Mapua, Salum A., Siria, Doreen J., Ngowo, Halfan S., Nangacha, Francis, Mgando, Joseph, Baldini, Francesco, González Jiménez, Mario, Ferguson, Heather M., Wynne, Klaas, Selvaraj, Prashanth, Babayan, Simon A., Okumu, Fredros O.“…METHODS: Laboratory-reared Anopheles arabiensis females were fed on humans, chickens, goats or bovines, then held for 6 to 8 h, after which they were killed and preserved in silica. The sample size was 2000 mosquitoes (500 per host species). Five individuals of each host species were enrolled to ensure genotype variability, and 100 mosquitoes fed on each. …”
Publicado 2019
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72086por Delatorre, Edson, de Abreu, Filipe Vieira Santos, Ribeiro, Ieda Pereira, Gómez, Mariela Martínez, dos Santos, Alexandre Araújo Cunha, Ferreira-de-Brito, Anielly, Neves, Maycon Sebastião Alberto Santos, Bonelly, Iule, de Miranda, Rafaella Moraes, Furtado, Nathália Dias, Raphael, Lidiane Menezes Souza, da Silva, Lucileis de Fátima Fernandes, de Castro, Márcia Gonçalves, Ramos, Daniel Garkauskas, Romano, Alessandro Pecego Martins, Kallás, Esper Georges, Vicente, Ana Carolina Paulo, Bello, Gonzalo, Lourenço-de-Oliveira, Ricardo, Bonaldo, Myrna Cristina“…We found two YFV sub-clade 1E lineages circulating in NHP from Goiás state (GO), resulting from independent viral introductions into the Araguaia tributary river basin: while one strain from 2017 clustered intermingled with Venezuelan YFV strains from 2000, the other YFV strains sampled in 2015 and 2017 clustered with sequences of the current YFV outbreak in the Brazilian Southeastern region (named YFV(2015-2018) lineage), displaying the same molecular signature associated to the current YFV outbreak. …”
Publicado 2019
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72087por Iunes, Roberto, Uribe, Manuela Villar, Torres, Janet Bonilla, Garcia, Marina Morgado, Alvares-Teodoro, Juliana, de Assis Acurcio, Francisco, Junior, Augusto Afonso Guerra“…The continuity of post-trial treatment was only incorporated in the 2000s by the Helsinki Declaration. The Universal Declaration on Bioethics and Human Rights, published in 2006, points out that post-trial continuity may present a broader scope than just the availability of the investigated medicine. …”
Publicado 2019
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72088por Petek, Bradley J., Bennett, Daniel N., Ngo, Christian, Chan, Paul S., Nallamothu, Brahmajee K., Bradley, Steven M., Tang, Yuanyuan, Hayward, Rodney A., van Walraven, Carl, Goldberger, Zachary D.“…DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study used a nationwide cohort from the American Heart Association Get With the Guidelines–Resuscitation IHCA registry to derive a sample of 96 509 patients from 716 US hospitals who experienced IHCA from January 1, 2000, to January 26, 2016. Data analysis began in January 2018 and concluded in June 2018. …”
Publicado 2019
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72089“…South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK355894/ Unless otherwise noted, all abstracts presented at ENDO are embargoed until the date and time of presentation. …”
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72090“…Background: Parathyroid carcinoma is a rare cause of primary hyperparathyroidism (0.74%), with an incidence of 0.36 (2000-2012), age presentation between 44-54 y/o, and symptoms associated with neck mass, bone and renal disease, as a consequence of marked hypercalcemia and elevated Parathyroid Hormone (PTH)(1). …”
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72091por Kumar, Vishak, Usmani, Sabahat, Alam, Sami, Fraz, Muhammad, Patel, Dutt, Goparaju, Pruthvi, Burphy, Thomas, Fayyaz, Tabassum, Noor, Nida, Suleman, Amer“…J et al., Clin Auton Res. 2000. October; 10(5): 293-303. Unless otherwise noted, all abstracts presented at ENDO are embargoed until the date and time of presentation. …”
Publicado 2019
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72092por Kamilaris, Crystal, Mandl, Adel, Simonds, William, Weinstein, Lee, Agarwal, Sunita, Blau, Jenny“…Melanoma has been observed in MEN1 with 9 cases described in the literature, including 2 cases with unknown primary site (Nord et al. 2000; Baldauf et al. 2009; Brown et al. 2015). Clinical Case: A 45 year old man with MEN1 syndrome manifesting as primary hyperparathyroidism, metastatic pancreatic neuroendocrine tumor (NET), Zollinger-Ellison syndrome, nonfunctional pituitary microadenoma, anterior mediastinal mass and skin angiofibromas presented with a left neck mass that developed over 1 year. …”
Publicado 2019
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72093“…METHODS: Data were obtained from Optum Clinformatics(TM) DataMart covering May 1, 2000 to March 30, 2016. Following a 6 month lead-in period of consistent use of Synthroid(®), patients were categorized as continuous users of Synthroid(®) or switchers if they stopped use of Synthroid(®) and filled a prescription for an alternative LT4. …”
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72094“…ACTH on day 6 of admission was greater than 2000, consistent with primary adrenal insufficiency. …”
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72095por Ylli, Dorina, Lima, Cristiane, Wu, Di, Gitterman, Adam L, Fernandez, Stephen J, Mete, Mihriye, Burman, Kenneth Dale, Wartofsky, Leonard“…Background: Although thyroid cancer is considered to have generally a good prognosis, approximately 2000 patients a year die as a consequence of progressive disease. …”
Publicado 2019
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72096por Patel, Dhaval, King, Timothy, Kebebew, Electron, Nilubol, Naris, Boufraqech, Myriem“…To identify the role of glutaminolysis in cancer cell growth, we carried out cell growth assay in three cancer cell lines (BCPAP and 8505c with BRAF(V600E),TPC1 with BRAF(wild-type)) in the presence of increasing concentration of the pharmacological inhibitor of GLS CB-839 (10, 100, 500 and 2000 nM). CB-839 significantly reduced the cell growth at nanomolar concentrations. …”
Publicado 2019
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72097por Seneviratne Epa, Dilan, Ng, Elisabeth, Nagalingam, Vathy, Schneider, Hans, Bach, Leon, Sztal-Mazer, Shoshana“…Diabetic Med 2005; 22: 1766‐69, (3) Krebs et al. NZ Med J 2000; 113: 379‐81.…”
Publicado 2019
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72098“…J Clin Endocrinol Metab,87(2), 489-99 2. Canaris G, et al. (2000). The Colorado Thyroid Disease Prevalence Study. …”
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72099por Touraine, Philippe, Mattsson, Anders, Burman, Pia, Van Beek, Andre, Aydin, Ferah, Kelepouris, Nicky, Feldt-Rasmussen, Ulla, Camacho-Hubner, Cecilia“…Anterior pituitary dysfunction, although well recognized, has been reported in only 5-20% of patients and most clinical information is primarily described in pediatric patients (Kaltsas G et al. JCEM 85: 1370-1376, 2000) with little information on pituitary function in adults with LCH. …”
Publicado 2019
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72100por Guzman, Heidi, Gallagher, Emily, Belbin, Gillian, Cullina, Sinead, Haber, Richard, Cho, Judy, Kenny, Eimear, Abdul-Husn, Noura“…The estimated prevalence of pathogenic RET variant carriers in BioMe was ~1 in 2000. Based on EHRs, only 3 carriers (20%) were identified from usual clinical care as having the diagnosis of MEN2A. …”
Publicado 2019
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