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  1. 72761
    “…PURPOSE: Noonan syndrome and related disorders are genetic conditions affecting 1:1000–2000 individuals. Variants causing hyperactivation of the RAS/MAPK pathway lead to phenotypic overlap between syndromes, in addition to an increased risk of pediatric tumors. …”
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    RASopathy Cohort of Patients Enrolled in a Brazilian Reference Center for Rare Diseases: A Novel Familial LZTR1 Variant and Recurrent Mutations
  2. 72762
    “…Baseline examinations were performed between 2000 and 2004, with follow-up on all-cause and CHD mortality through May 31, 2018. …”
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    Associations of Cardiometabolic Multimorbidity With All-Cause and Coronary Heart Disease Mortality Among Black Adults in the Jackson Heart Study
  3. 72763
    “…We constructed climatic models to evaluate the potential impact of climate change on the distribution of crocodile lizards for the period 2000 to 2100 and determined the key environmental factors that affect the dispersal of this endangered species. …”
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    Climate Change and Dispersal Ability Jointly Affects the Future Distribution of Crocodile Lizards
  4. 72764
    “…Background: Ghana joined the Global Programme to Eliminate Lymphatic Filariasis (GPELF), established in the year 2000, with the aim of eliminating the disease as a public health problem through annual mass treatment of entire endemic populations. …”
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    A Comparative Study of Lymphatic Filariasis-Related Perceptions among Treated and Non-Treated Individuals in the Ahanta West Municipality of Ghana
  5. 72765
    “…In each study room, the bedrails, overbed table, and sink were divided into 2 equal halves, or sides, labeled left and right, with sample areas of 2,000 cm(2), 1,750 cm(2), and 400 cm(2), respectively. …”
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    Measuring the impact of an enhanced strategy for daily disinfection in acute-care hospital rooms
  6. 72766
    “…The risk of developing acute pancreatitis is approximately 5 percent with serum triglycerides >1000 mg/dL and 10 to 20 percent with triglycerides >2000 mg/dL. This is the case of a 63-year-old female who came to the Emergency Department with acute onset of abdominal pain, located at the mid-epigastric region, radiating to back, 10/10 in a scale of severity, no alleviating or aggravating factor, accompanied by nausea, 5 episodes of bilious emesis. …”
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    ODP135 A New Life-Saving Treatment not yet Included in Guidelines for Recurrent Severe Hypertriglyceridemia-Induced Pancreatitis
  7. 72767
    “…METHODS: This was a retrospective cohort study of pediatric patients (≥3 and <16 years) with >1 medication prescription for daily injectable somatropin from 1 st July 2000 to 31 st December 2020 in the IQVIA Medical Research DATA (IMRD) database. …”
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    ODP392 Persistence with daily growth hormone treatment among pediatric patients with growth hormone deficiency in the UK
  8. 72768
    “…HAMA antibodies came back elevated at 552 ng/mL. REFERENCE: Klee, G., 2000. Human Anti-Mouse Antibodies. Archives of Pathology & Laboratory Medicine, 124(6), pp.921-923. …”
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    RF35 | PSAT304 A Case of COVID-19 Infection; COVID-19 mRNA-Based Vaccine Induced Human Anti-Mouse Antibodies (HAMA) Interfering With TSH Testing
  9. 72769
    “…The University of Chicago Monogenic Diabetes Registry has enrolled over 3800 participants from over 2000 families. Participants represent all 50 states and more than 20 different countries. …”
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    Insight on Diagnosis and Treatment From Over a Decade of Research Through the University of Chicago Monogenic Diabetes Registry
  10. 72770
    “…We included peer-reviewed articles published in English between January 2000 and September 2020. The search strategy was developed in collaboration with a research librarian. …”
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    Exploring risk and protective factors for adolescent dating violence across the social-ecological model: A systematic scoping review of reviews
  11. 72771
    “…MATERIALS AND METHODS: Eighty-four male New Zealand White bucks (1.750–2.000 kg) were randomly divided into seven groups (12 each). …”
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    Hepatoprotective and renoprotective effects of silymarin against salinomycin-induced toxicity in adult rabbits
  12. 72772
    “…Prognostic impact was evaluated in 120 patients with follow-up data from the HIT2000 medulloblastoma trial or HIT registries. CTNNB1 mutations were present in 92.2%, and APC mutations in 6.8% of samples. …”
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    Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas
  13. 72773
    “…METHODS: We systematically searched Embase, PubMed and the Cochrane library for published studies from January 2000 to December 2020. Included studies reported any information on the proportion of attainment of optimal glycated haemoglobin (HbA1c), blood pressure (BP) and low-density lipoprotein cholesterol (LDLC) goals and/or prevalence of five diabetes complications (diabetic peripheral neuropathy, retinopathy, nephropathy, foot ulcers and peripheral arterial disease). …”
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    Indicators of optimal diabetes care and burden of diabetes complications in Africa: a systematic review and meta-analysis
  14. 72774
    “…A systematic search and meta-analysis of studies from January 2000 to January 2022 was performed. RESULTS: 41 patients were treated (HF-RT:15, CF-RT:26). …”
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    Moderately hypofractionated versus conventionally fractionated radiation therapy with temozolomide for young and fit patients with glioblastoma: an institutional experience and meta-analysis of literature
  15. 72775
    “…A comparative analysis of two periods (1981–2000 vs 2001–2020) was conducted to analyze changes in epidemiology and outcome over time. …”
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    Forty-Year Trends in Cardiac Implantable Electronic Device Infective Endocarditis
  16. 72776
    “…Genotype G has been exclusively circulating since the early 2000s. Seven clades were identified for genotype G using SH sequence-based classification. …”
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    Nationwide and long-term molecular epidemiologic studies of mumps viruses that circulated in Japan between 1986 and 2017
  17. 72777
    “…METHODS: A retrospective study was conducted between January 2000 and September 2021. Patients with pSLE were identified from multiple sources: computerized hospital archives, registry of referring pediatricians, adult specialists in internal medicine and the French National Registry for rare diseases. …”
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    Systemic lupus of pediatric onset in Afro-Caribbean children: a cohort study in the French West Indies and French Guiana
  18. 72778
    “…METHODS: Consecutive patients who breast cancer developed recurrence at our tertiary referral centre between 2000 and 2015 were included. Clinicopathological and treatment data were assessed using descriptive statistics. …”
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    Breast cancer recurrence: factors impacting occurrence and survival
  19. 72779
    “…METHODS AND DESIGN: A systematic search was conducted using PubMed, EMBASE, Medline, PsycINFO, and CINAHL databases from 1/1/2000 to 1/6/2020. In this systematic review and meta-analysis, we analyzed the psychological impact on confirmed/suspected cases, healthcare workers and the general public during the Severe Acute Respiratory Syndrome (SARS) outbreak and Coronavirus disease (COVID-19) epidemics. …”
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    Psychological impact on healthcare workers, general population and affected individuals of SARS and COVID-19: A systematic review and meta-analysis
  20. 72780
    “…The investigation systematically searched PubMed, Medline, Web of Science, Cochrane Library, and Google Scholar (21-year span, between 2000 and 2021) to retrieve articles reporting the diagnostic role of miRNA panels in detecting CRC. …”
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    MicroRNA panels as diagnostic biomarkers for colorectal cancer: A systematic review and meta-analysis
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