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  1. 73661
    “…METHODS: We searched PubMed, CENTRAL, ISI Web of Sciences, Scopus, OVID (Medline), CINAHL, LILACS, CNKI and OpenGrey for randomized controlled trials (RCTs) and cluster RCTs conducted in LMICs from January 2000 to September 2021. Two reviewers independently screened studies, extracted data, assessed risk of bias and certainty of evidence. …”
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    Interventions to increase the uptake of cervical cancer screening in low- and middle-income countries: a systematic review and meta-analysis
  2. 73662
    “…METHODS: A systematic search strategy was used to identify eligible studies from MEDLINE, Embase, PsycINFO, Scopus, CINAHL, Cochrane Library, INFORMIT, IEEE Xplore and Clinical Trial Registries, published between January 2000 and August 2022. Digital interventions to increase vegetable intake were included, with effective interventions identified based on statistically significant improvement in vegetable intake. …”
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    Digital behaviour change interventions to increase vegetable intake in adults: a systematic review
  3. 73663
    “…In a previous screening of 2000 approved drugs, natural products, and bioactive substances, various non-steroidal anti-inflammatory drugs (NSAIDs) were found to inhibit P2X3R-mediated currents. …”
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    Diclofenac and other non-steroidal anti-inflammatory drugs (NSAIDs) are competitive antagonists of the human P2X3 receptor
  4. 73664
    “…DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study included patients with mild cognitive impairment (cohort 1; enrollment in 2000-2005) and replication in cohort 2 from the Swedish BioFINDER-2 study, including both cognitively unimpaired individuals and those with cognitive impairment (enrollment in 2017-2022). …”
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    Mitigating the Associations of Kidney Dysfunction With Blood Biomarkers of Alzheimer Disease by Using Phosphorylated Tau to Total Tau Ratios
  5. 73665
    “…We enrolled patients during the 10-year study period (January 1, 2000, to December 31, 2010), and each patient was followed up for 5 years. …”
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    The adjusted impact of different severities of acute exacerbations and medications on the risk of developing dementia in COPD patients
  6. 73666
    “…Pneumococcal conjugate vaccines were introduced in the United States (US) in 2000 (7-valent [PCV7]) and 2010 (13-valent [PCV13]). …”
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    Incidence of non-invasive all-cause pneumonia in children in the United States before and after the introduction of pneumococcal conjugate vaccines: a retrospective claims database analysis
  7. 73667
    “…There was a comparable increase in SV (crystalloids: 65 (54–74 ml; colloids: 67.5 (60–75.25 ml) and total volume infused (crystalloids: 2575 (2000–4210) ml; colloids: 2435 (1760–3480) ml; and controls: 2210 (1658–3000) ml). …”
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    Goal-directed fluid therapy using uncalibrated pulse contour analysis and balanced crystalloid solutions during hip revision arthroplasty: a quality implementation project
  8. 73668
    “…The LFA-REAL ClinRO correlated with Physician Global Assessment (r=0.39, 0.65 and 0.74, p<0.001), British Isles Lupus Assessment Group Index (r=0.43, 0.67 and 0.73, p<0.001) and SLE Disease Activity Index-2000 (r=0.35, 0.60 and 0.62, p<0.001). The LFA-REAL ClinRO arthralgia/arthritis score correlated well with active joint counts (r=0.54, 0.73 and 0.68, p<0.001) and the mucocutaneous global score correlated strongly with Cutaneous Lupus Erythematosus Disease Area and Severity Index total activity (r=0.57, 0.77 and 0.81, p<0.001). …”
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    Evaluation of the LFA-REAL clinician-reported outcome (ClinRO) and patient-reported outcome (PRO): prespecified analysis of the phase III ustekinumab trial in patients with SLE
  9. 73669
    “…The purpose of this project was to develop asynchronous faculty development to rapidly educate/re-educate > 2000 clinical faculty spread across geographic sites and clinical disciplines on components of a well-written narrative and methods to minimize bias in the assessment of students. …”
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    Creation of an asynchronous faculty development curriculum on well-written narrative assessments that avoid bias
  10. 73670
    “…RESULTS: Eleven studies (published between 2000 and 2022) were included in this study, including 1,131 SPLC patients. …”
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    Evaluation of surgical outcomes and prognostic factors of second primary lung cancer based on a systematic review and meta-analysis
  11. 73671
    “…METHODS: After Institutional Review Board approval, a retrospective review of consecutive patients who underwent DFR between December 2000 to September 2020 was performed using a single-institutional database. …”
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    Clinical outcomes of cemented distal femur replacements with all-polyethylene tibial components for oncologic indications
  12. 73672
    “…METHODS: 63 PB/ELBW and 64 controls born in Norway in the periods 1982–1985, 1991–1992, and 1999–2000 were examined with echocardiography. LV ejection fraction (EF) and LV global longitudinal strain (GLS) were measured. …”
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    Myocardial function including estimates of myocardial work in young adults born very preterm or with extremely low birthweight - a cohort study
  13. 73673
    “…PARTICIPANTS: 141 765 women aged 20 years and older with a diagnosis of invasive breast cancer between 1 January 2000 and 31 December 2020. MAIN OUTCOME MEASURES: Four model building strategies comprising two regression (Cox proportional hazards and competing risks regression) and two machine learning (XGBoost and an artificial neural network) approaches. …”
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    Development and internal-external validation of statistical and machine learning models for breast cancer prognostication: cohort study
  14. 73674
    “…Addressing the CDKN2A/2B deletions’ additive prognostic effect in current risk-stratification algorithms, we present a retrospective study of a Greek pediatric ALL cohort comprising 247 patients studied over a 24-year period (2000–2023). Herein, we provide insight regarding the correlation with disease features, MRD clearance, and independent prognostic significance for this ALL cohort treated with contemporary BFM-based treatment protocols. …”
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    The Prognostic Effect of CDKN2A/2B Gene Deletions in Pediatric Acute Lymphoblastic Leukemia (ALL): Independent Prognostic Significance in BFM-Based Protocols
  15. 73675
    “…BACKGROUND: The share of people over 80 years in the European Union is estimated to increase two-and-a-half-fold from 2000 to 2100. A substantial share of older persons experiences fear of falling. …”
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    The association of fear of falling and physical and mental Health-Related Quality of Life (HRQoL) among community-dwelling older persons; a cross-sectional study of Urban Health Centres Europe (UHCE)
  16. 73676
    “…Data from the 200 Holter and 204 Zio cases was extrapolated to model outcomes for 1 year, assuming 2000 patients undergo ECG monitoring per year (based on annual figures for our centre). …”
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    Zio XT for ambulatory heart rhythm monitoring: a cost-benefit analysis
  17. 73677
    “…The patient cohort was identified via the Danish Pacemaker and ICD Registry and consisted of consecutive Danish patients undergoing a CRT de novo implantation or an upgrade to CRT, from 01.01.2000 to 31.08.2018. Upgrade from a CRT pacemaker to a CRT defibrillator, and simple device replacement procedures were not included. …”
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    Long-term mortality in cardiac resynchronization therapy upgrade procedures compared with de novo implantations - a nationwide cohort study
  18. 73678
    “…METHODS: Baseline surveys were conducted in 5,997 households, randomly selected from 24 clusters (neighbourhoods with on average 2000 houses and 250 households inspected) in the metropolitan area of Cucuta, Colombia. …”
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    Risk of dengue, Zika, and chikungunya transmission in the metropolitan area of Cucuta, Colombia: cross-sectional analysis, baseline for a cluster-randomised controlled trial of a novel vector tool for water containers
  19. 73679
    “…We included patients with type 2 DM who were aged 40 years or older and admitted to hospital between Jan. 1, 2000, and May 26, 2021, and excluded those with pre-existing chronic kidney disease and those who were already on statins or without follow-up at an affiliated outpatient clinic within 90 days after discharge. …”
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    Statin initiation and risk of incident kidney disease in patients with diabetes
  20. 73680
    “…All databases published from January 2000 to August 2022. The treatment group was treated with sivelestat and the control group was given normal saline. …”
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    Effect of Sivelestat in the Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis
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