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  1. 73681
    “…BACKGROUND: 22q11.2 deletion syndrome (22q11.2DS) is the most common chromosomal interstitial-deletion disorder, occurring in approximately 1 in 2000 to 6000 live births. Affected individuals exhibit variable clinical phenotypes that can include velopharyngeal anomalies, heart defects, T-cell-related immune deficits, dysmorphic facial features, neurodevelopmental disorders, including autism, early cognitive decline, schizophrenia, and other psychiatric disorders. …”
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    Deep psychophysiological phenotyping of adolescents and adults with 22q11.2 deletion syndrome: a multilevel approach to defining core disease processes
  2. 73682
    “…METHODS: PubMed, PsycINFO, and Cochrane CENTRAL were searched for randomized controlled trials (RCTs) published between January 2000 and July 2022. We included RCTs comparing digital CBT with any comparison group in adolescents or adults (aged ≥12 years) for anxiety or depression. …”
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    Skill Enactment and Knowledge Acquisition in Digital Cognitive Behavioral Therapy for Depression and Anxiety: Systematic Review of Randomized Controlled Trials
  3. 73683
    “…Basic information about the subjects was collected, including gender, age, body mass index (BMI), course of disease, evidence of previous tuberculosis, Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) score, and the use of glucocorticoids and immunosuppressants. …”
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    Latent Tuberculosis Infection and Associated Factors in Patients with Systemic Lupus Erythematosus: a Multicenter, Cross-Sectional Study
  4. 73684
    “…The following electronic databases were searched: Cochrane Library, EMBASE, PubMed, Web of Science, PsycINFO, ERIC, AMED and CINAHL for papers published from January 2000 to May 2022. Studies were screened by two independent investigators with a third resolving discrepancies. …”
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    A systematic review of non-coding RNA genes with differential expression profiles associated with autism spectrum disorders
  5. 73685
    “…Patient recruitment will be completed in April 2025, and the target number of enrolled patients is 2000. DISCUSSION: This study will provide evidence about the surgical outcomes, oncologic outcomes, and patient satisfaction with RNSM and endoscopic nipple-sparing mastectomy (NSM), compared with conventional NSM. …”
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    Mastectomy with Reconstruction Including Robotic Endoscopic Surgery (MARRES): a prospective cohort study of the Korea Robot-Endoscopy Minimal Access Breast Surgery Study Group (KoREa-BSG) and Korean Breast Cancer Study Group (KBCSG)
  6. 73686
    “…Similarly, potassium silicate was the most effective chemical inducer followed by salicylic acid, each at 2000 ppm. They reduced the linear growth of F. solani by 62.3 and 55.7%; M. phaseolina by 60.7 and 53.1%; and F. oxysporum by 60.3 and 53%, respectively. …”
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    Induction of Systemic Resistance in Hibiscus sabdariffa Linn. to Control Root Rot and Wilt Diseases Using Biotic and Abiotic Inducers
  7. 73687
    “…INTRODUCTION: Measles is a highly infectious ribonucleic acid (RNA) virus whose prevalence in the United States has continued to increase despite being declared eliminated in 2000,1 and larger outbreaks have been noted among those who elect not to vaccinate.2 The recommended live-attenuated measles, mumps, and rubella (MMR) vaccine schedule for pediatrics includes one routine dose at 12–15 months of age and a second dose between 4–6 years of age with at least 28 days in between dose administration.1–2 Measles-associated complications include otitis media, pneumonia, laryngotracheobronchitis, diarrhea, and corneal ulceration.2 Patients may also develop central nervous system complications, including primary measles encephalitis, acute post-infectious measles encephalomyelitis, measles inclusion body encephalitis, and subacute sclerosing panencephalitis. …”
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    Primary Measles Encephalitis
  8. 73688
    por Piroutek, Mary Jane
    Publicado 2020
    “…With introduction of conjugate vaccines for Haemophilus influenzae type B (Hib) and Streptococcus pneumoniae in the United States in 1987 and 2000 respectively, the incidence of bacterial meningitis is low, but still present.3–7 The most recent American Academy of Pediatrics practice guidelines no longer recommend routine lumbar puncture on children presenting with simple febrile seizures.2 A review of the current literature shows that bacterial meningitis in children after a complex febrile seizure is unexpected when the clinical examination is not suggestive of meningitis or encephalitis.5–8 The goal of this mTBL is for residents to feel comfortable counseling parents about their child currently in the emergency department and the future risk of recurrence. …”
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    Febrile Seizure Team-based Learning
  9. 73689
    “…Methods: Our study extracted data from the Surveillance, Epidemiology, and End Results (SEER) database for the period 2000 to 2018. Cox regression model analysis was performed to identify risk factors independently affecting survival. …”
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    Acinic Cell Carcinoma in the 21st Century: A Population-Based Study from the SEER Database and Review of Recent Molecular Genetic Advances
  10. 73690
    “…In total, 2242 Palestinian children have been killed by Israeli military forces between the years 2000 and 2022. Childhood is not a given for Palestinian children, but instead something that must be determined, retrieved, and understood within a complex web of implications mandated by the dynamics of power that are in play. …”
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    Developing a National Strategy for Child and Adolescent Mental Health in Palestine
  11. 73691
    “…The weighted mean [SE] age was 47.3 [0.2] years; 24 539 (weighted proportion, 51.5%) were women. From the 1999-2000 cycle to the 2017 to March 2020 cycle, the estimated prevalence of the 5 lifestyle factors showed divergent trends, with increasing prevalence of never smoking (from 49.4% [95% CI, 46.4%-52.4%] to 57.7% [95% CI, 55.5%-59.9%]; difference, 8.2% [95% CI, 4.5%-12.0%]), healthy diet (from 19.3% [95% CI, 16.0%-22.6%] to 24.5% [95% CI, 21.5%-27.5%]; difference, 5.2% [95% CI, 0.8%-9.7%]), and sufficient physical activity (from 55.7% [95% CI, 51.8%-59.6%] to 69.1% [95% CI, 67.2%-71.1%]; difference, 13.4% [95% CI, 9.0%-17.8%]), while prevalence of healthy weight decreased from 33.1% (95% CI, 30.5%-35.6%) to 24.6% (95% CI, 22.6%-26.7%; difference, −8.4% [95% CI, −11.8% to −5.1%]) (all P < .001 for trend). …”
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    Trends in Self-Reported Adherence to Healthy Lifestyle Behaviors Among US Adults, 1999 to March 2020
  12. 73692
    “…METHODS: This is a retrospective cohort study on BC patients undergoing radical cystectomy (RC) in Québec province in 2000–2015, as registered in the provincial health administration databases. …”
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    Chronic prednisone, metformin, and nonsteroidal anti-inflammatory drug use and clinical outcome in a cohort of bladder cancer patients undergoing radical cystectomy in Québec, Canada
  13. 73693
    “…Participants included consecutive patients with OCSCC diagnosed between 2000 and 2020. Patients with postradiation OCSCC were matched with patients with sporadic OCSCC using age, year of diagnosis, sex, and anatomic subsites. …”
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    Comparison of Clinical Outcomes, Pathologic Characteristics, and Immune-Related Features of Postradiation vs Sporadic Oral Cavity Squamous Cell Carcinoma
  14. 73694
    “…Initial findings from the prediction curve on all 208 lesions confirmed that a 48-h SUV(max) was the best predictor of lesion radiation dose and permitted calculation of the (131)I activity required to achieve a lesional threshold radiation dose (2000 cGy) within defined confidence intervals. CONCLUSIONS: Based on MIRD lesion-absorbed dose estimates and regression statistics, we report on the feasibility of a new single-timepoint (124)I-PET-based dosimetry biomarker for RAI in patients with mDTC. …”
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    The use of single-timepoint images to link administered radioiodine activity (MBq) to a prescribed lesion radiation-absorbed dose (cGy): a regression-based prediction interval tool for the management of well-differentiated thyroid cancer patients
  15. 73695
    “…METHODS: In this prospective, population-based cohort study and nested case–control study, 9,940 participants in Germany were enrolled between 2000 and 2002 by their general practitioners and followed for up to 17 years. …”
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    Alzheimer’s polygenic risk scores, APOE, Alzheimer’s disease risk, and dementia-related blood biomarker levels in a population-based cohort study followed over 17 years
  16. 73696
    “…Articles published in English between the years 2000 and 2022 with a substantial focus on community TB implementation models were considered for inclusion. …”
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    Mapping the effectiveness of the community tuberculosis care programs: a systematic review
  17. 73697
    por Coulombe, Louis-Philippe, Benneke, Björn, Challener, Ryan, Piette, Anjali A. A., Wiser, Lindsey S., Mansfield, Megan, MacDonald, Ryan J., Beltz, Hayley, Feinstein, Adina D., Radica, Michael, Savel, Arjun B., Dos Santos, Leonardo A., Bean, Jacob L., Parmentier, Vivien, Wong, Ian, Rauscher, Emily, Komacek, Thaddeus D., Kempton, Eliza M.-R., Tan, Xianyu, Hammond, Mark, Lewis, Neil T., Line, Michael R., Lee, Elspeth K. H., Shivkumar, Hinna, Crossfield, Ian J. M., Nixon, Matthew C., Rackham, Benjamin V., Wakeford, Hannah R., Welbanks, Luis, Zhang, Xi, Batalha, Natalie M., Berta-Thompson, Zachory K., Changeat, Quentin, Désert, Jean-Michel, Espinoza, Néstor, Goyal, Jayesh M., Harrington, Joseph, Knutson, Heather A., Kreidberg, Laura, López-Morales, Mercedes, Shporer, Avi, Sing, David K., Stevenson, Kevin B., Aggarwal, Keshav, Ahrer, Eva-Maria, Alam, Munazza K., Bell, Taylor J., Blecic, Jasmina, Caceres, Claudio, Carter, Aarynn L., Casewell, Sarah L., Crouzet, Nicolas, Cubillos, Patricio E., Decin, Leen, Fortney, Jonathan J., Gibson, Neale P., Heng, Kevin, Henning, Thomas, Iro, Nicolas, Kendrew, Sarah, Lagage, Pierre-Olivier, Leconte, Jérémy, Lendl, Monika, Lothringer, Joshua D., Mancini, Luigi, Mikal-Evans, Thomas, Molaverdikhani, Karan, Nikolov, Nikolay K., Ohno, Kazumasa, Palle, Enric, Piaulet, Caroline, Redfield, Seth, Roy, Pierre-Alexis, Tsai, Shang-Min, Venot, Olivia, Wheatley, Peter J.
    Publicado 2023
    “…Close-in giant exoplanets with temperatures greater than 2,000 K (‘ultra-hot Jupiters’) have been the subject of extensive efforts to determine their atmospheric properties using thermal emission measurements from the Hubble Space Telescope (HST) and Spitzer Space Telescope(1–3). …”
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    A broadband thermal emission spectrum of the ultra-hot Jupiter WASP-18b
  18. 73698
    “…Moreover, the JK5G group had a lower incidence of anemia (63.33% vs. 13.33%, p < 0.001), decreased lymphocyte count (20.00% vs. 0%, p = 0.010), decreased appetite (53.33% vs. 16.67%, p = 0.003), nausea (33.33% vs. 6.67%, p = 0.010), and asthenia (30.00% vs. 6.67%, p = 0.017) than the control group. …”
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    JK5G postbiotics attenuate immune-related adverse events in NSCLC patients by regulating gut microbiota: a randomized controlled trial in China
  19. 73699
    “…Retrospective analysis showed that the patenting of sensors for continuous glucose monitoring had positive trend over the analyzed period (2000–2022). Leading development companies are Dexcom Inc., Abbott Diabetes Care Inc., Medtronic Minimed Inc., Roche Diabetes Care Inc., Roche Diagnostics Operations Inc., Roche Diabetes Care Gmbh, and Ascensia Diabetes Care Holdings Ag, among others. …”
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    Patent analysis of digital sensors for continuous glucose monitoring
  20. 73700
    “…Treatments included three diets containing increasing inorganic P from monocalcium P (0.11%, 0.20%, and 0.28% aP), or five diets with increasing phytase (500, 1,000, 1,500, 2,000, or 2,500 FTU/kg) added to the diet containing 0.11% aP. …”
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    Determining the phosphorus release curve for Smizyme TS G5 2,500 phytase from 500 to 2,500 FTU/kg in nursery pig diets
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