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  1. 73861
    “…All patients were assessed for disease activity using the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) scale. In addition, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) inflammatory parameters were determined in each patient. …”
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    Differential approach to peripheral blood cell ratios in patients with systemic lupus erythematosus and various manifestations
  2. 73862
    “…We will enroll children at 6 months of age and follow up on a monthly basis up to 24 months of age. A total of 2000 children, 400 in each arm, will be enrolled to detect a 20% reduction in the prevalence of stunting among children aged 24 months. …”
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    Specialized Nutritious Food Combined With Cash Transfers and Social and Behavior Change Communication to Prevent Stunting Among Children Aged 6 to 23 Months in Pakistan: Protocol for a Cluster Randomized Controlled Trial
  3. 73863
    por Delgado-Enciso, Ivan, Paz-Garcia, Juan, Barajas-Saucedo, Carlos E, Mokay-Ramírez, Karen A, Meza-Robles, Carmen, Lopez-Flores, Rodrigo, Delgado-Machuca, Marina, Murillo-Zamora, Efren, Toscano-Velazquez, Jose A., Delgado-Enciso, Josuel, Melnikov, Valery, Walle-Guillen, Mireya, Galvan-Salazar, Hector R., Delgado-Enciso, Osiris G., Cabrera-Licona, Ariana, Guzman-Esquivel, José, Montes-Galindo, Daniel A., Hemandez-Rangel, Alejandra E., Montes-Diaz, Patricia, Rodriguez-Sanchez, Iram P, Martinez-Fierro, Margarita L, Garza-Veloz, Idalia, Tiburcio-Jimenez, Daniel, Zaizar-Fregoso, Sergio A, Ramirez-Flores, Mario, Gaytan-Sandoval, Gustavo, Martinez-Perez, Carlos R., Espinoza-Gómez, Francisco, Rojas-Larios, Fabián, Hirsch-Meillon, Michael J., Barrios-Navarro, Enrique, Oviedo-Rodriguez, Vladimir, Baltazar Rodriguez, Luz M., Paz-Michel, Brenda A.
    Publicado 2020
    “…RESULTS: The experimental treatment decreased the risk for hospitalization by 92% (adjusted RR=0.08, 95% CI: 0.01–0.50, P=0.007), with a 43-fold increase in the probability of achieving an acceptable symptom state on day 5 (adjusted RR= 42.96, 95% CI: 9.22–200.0, P<0.001). Intravenous + nebulized administration was better than nebulized administration alone, but nebulized administration was better than usual medical care alone. …”
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    Patient-Reported Health Outcomes After Treatment of COVID-19 with Nebulized and/or Intravenous Neutral Electrolyzed Saline Combined with Usual Medical Care Versus Usual Medical care alone: A Randomized, Open-Label, Controlled Trial.
  4. 73864
    “…STUDY DESIGN: We performed a population-based cohort study nested in the Medicaid Analytic eXtract (MAX, 2000–2014) and IBM MarketScan Research Database (MarketScan, 2003–2015). …”
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    Hydroxychloroquine early in pregnancy and risk of birth defects
  5. 73865
    “…METHODS AND RESULTS: All patients undergoing CRT implantation at our institution between November 2000 and January 2015 were enrolled. The study endpoints were (i) a composite of ventricular assist device (VAD) implantation, heart transplantation, or all‐cause mortality; and (ii) reverse remodelling (improvement of LVEF ≥ 10% or reduction of left ventricular end‐systolic volume ≥ 15%). …”
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    Differential effect of cardiac resynchronization therapy in patients with diabetes mellitus: a long‐term retrospective cohort study
  6. 73866
    “…Since the COVID-19 outbreak, the salient politicized discourses of blaming Chinese people for spreading the virus have fueled over 2000 reports of anti-Asian racial incidents and hate crimes in the United States. …”
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    Intergroup Contact, COVID-19 News Consumption, and the Moderating Role of Digital Media Trust on Prejudice Toward Asians in the United States: Cross-Sectional Study
  7. 73867
    por Kang, Youjeong, Hurdle, John
    Publicado 2020
    “…The latter runs exceptionally fast (on the order of tens-of-seconds for 2,000 documents). Machine Learning (ML): the output of the NLP BOW and Document Embedding models were fed to six different conventional machine learning systems (logistic regression, support vector machine, random forest, k-nearest neighbor clustering, a three-layer neural network, and Naïve Bayes). …”
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    Predictive Model for Risk of 30-Day Rehospitalization Using a Natural Language Processing/Machine Learning Approach Among Medicare Patients with Heart Failure
  8. 73868
    “…METHODS: Systematic literature searches in seven databases identified RCTs in healthy adults, or those at risk of disease, published between January 2000–April 2020. Two reviewers independently selected studies, extracted data and assessed risk of bias. …”
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    The effects of step-count monitoring interventions on physical activity: systematic review and meta-analysis of community-based randomised controlled trials in adults
  9. 73869
    “…SETTING: Data were extracted from relevant studies from January 1, 2000 to December 31, 2019 without limitations on country of study conduction. …”
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    A Comparison of Patient-Reported Outcome Measures of Quality of Life By Dialysis Modality in the Treatment of Kidney Failure: A Systematic Review
  10. 73870
    “…SETTING AND COUNTRY SELECTION: Global sample of countries for all years from 1989 to 2019, split into two categories: 17 treatment countries that started autocratising during 2000 to 2010, and 119 control countries that never autocratised from 1989 to 2019. …”
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    Autocratisation and universal health coverage: synthetic control study
  11. 73871
    “…Transfusion of 30 units of packed red cells, 40 units of fresh frozen plasma, 5 units of platelets, 2000IE of PPSB, 30mcg of desmopressin acetate, 5 grams of fibrinogen concentrate guided by repetitive viscoelastic testing was performed. …”
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    Anesthesia for double lung transplant in a patient with confirmed COVID-19 infection: a case report
  12. 73872
    “…Searches were carried out in Medline, Cochrane library, CINAHL, Embase and PsycINFO from 2000 to 27 January 2020. Data extraction and critical appraisal was undertaken by two independent reviewers. …”
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    Preventable medication harm across health care settings: a systematic review and meta-analysis
  13. 73873
    “…METHODS: We used data from 27,090 patients diagnosed with dementia between January 2000 and March 2016 from the Clinical Practice Research Datalink linked to Hospital Episodes Statistics data in England. …”
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    Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study
  14. 73874
    “…Using a portion of the Leiden data (n=2000), we compared 6 different machine learning methods and a naïve word-matching algorithm using 10-fold cross-validation. …”
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    Machine Learning Electronic Health Record Identification of Patients with Rheumatoid Arthritis: Algorithm Pipeline Development and Validation Study
  15. 73875
    “…METHODS: In TMB-301, a Phase 3 study, 40 TE patients with viral load (VL) >1000 copies/mL (c/mL) received an intravenous (IV) loading dose of IBA (2000mg) followed by maintenance doses (800mg IV) every 2 weeks combined with an optimized background regimen. …”
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    1008. Disease Severity Impact on Long-Term Virologic Response to Ibalizumab in Expanded Access Protocol (TMB-311)
  16. 73876
    “…Well-controlled persons (viral load < 2000) were proxies for chronic infection on long-term ART and uncontrolled for recently infected and initiated on ART. …”
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    1043. The impact of integrase strand transfer inhibitors (InSTIs) on weight gain among adults with HIV in clinical care
  17. 73877
    “…Healthy volunteers (n=8/cohort, 3:1 randomization) received SPR720 or placebo in single oral doses of ranging from 100 mg to 2000 mg or repeat total daily doses ranging from 500 mg to 1500 mg for 7 or 14 days. …”
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    1288. Phase 1 First-in-Human Single- and Multiple-Ascending Dose Trial Demonstrates Pharmacokinetics (PK) and Tolerability of SPR720, an Oral DNA GyrB Inhibitor for Mycobacterial Infections
  18. 73878
    “…Metformin will be started at 500 mg b.i.d. and escalated to 1000 mg b.i.d. 2 weeks thereafter (up to a maximum of 2000 mg daily). In addition, all participants will undergo a lifestyle intervention as part of the usual treatment consisting of a combination of an exercise program and dietary consultations. …”
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    Study protocol of a randomized, double-blind, placebo-controlled, multi-center trial to treat antipsychotic-induced weight gain: the Metformin-Lifestyle in antipsychotic users (MELIA) trial
  19. 73879
    “…BACKGROUND: The algal flora of the western group of the Azores archipelago (Islands of Flores and Corvo) has attracted the interest of many researchers on numerous past occasions (such as Drouet 1866, Trelease 1897, Gain 1914, Schmidt 1929, Schmidt 1931, Azevedo et al. 1990, Fralick and Hehre 1990, Neto and Azevedo 1990, Neto and Baldwin 1990, Neto 1996, Neto 1997, Neto 1999, Tittley and Neto 1996, Tittley and Neto 2000, Tittley and Neto 2005, Tittley and Neto 2006, Azevedo 1998, Azevedo 1999, Tittley et al. 1998, Dionísio et al. 2008, Neto et al. 2008). …”
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    Marine algal flora of Flores and Corvo Islands, Azores
  20. 73880
    “…METHODS: We investigated the role of polypyrimidine tract-binding protein-associated splicing factor (PSF) in cellular energy production, migration, and proliferation by targeting HIF-1α in vivo and in vitro PSF plasmids were transfected with liposome 2000 transfection reagent. Young C57/BL6J mice were kept in a hyperoxia environment, followed by indoor air, resulting in oxygen-induced retinopathy. …”
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    PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function
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