“…RESULTS: We identified three H3K4me3-lncRNA patterns that exhibited specific immune characteristics. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Extensive investigation of 3-(p-chlorophenyl)-2,3-dihydro-3-hydroxythiazolo(3,2-alpha)-benzimidazole-2-acetic acid (Wy-13,876) in BDF1 mice implanted with Lewis lung tumour has shown that it is an effective anti-tumour and anti-metastatic agent. …”
Enlace del recurso
Enlace del recurso

“…In the mol­ecule of the title compound, C(19)H(18)N(4)O(3)S, the central heterocylic ring system is oriented with respect to the trimethoxy­phenyl and 4-methyl­phenyl rings at dihedral angles of 1.1 (5) and 15.1 (5)°, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The two benzimidazole ring systems are essentially planar, with maximum deviations of 0.011 (4) and 0.023 (3) Å. The dihedral angle between these two ring systems is 25.87 (15)°. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the title compound, C(15)H(20)ClNO(3), the seven-membered ring adopts a distorted boat–sofa conformation; the methyl­ene C atoms of this ring are coplanar with the benzene ring. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The bicyclic mol­ecule of the title compound, C(9)H(12)O(3), contains two five-membered rings with different functional groups, viz. a ketone and an ester. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the mol­ecule of the title compound, C(17)H(15)N(5)O(3)S, the planar central heterocylic ring system is oriented at dihedral angles of 5.32 (4) and 9.41 (4)°, respectively with respect to trimethoxy­phenyl and pyridine rings. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the title coordination complex, [Zn(C(22)H(12)O(6))(H(2)O)(2)](n) or [Zn(H(2)nba)(H(2)O)(2)](n) (H(2)nba is 2,2′-dihydr­oxy-1,1′-bi­naph­thyl-3,3′-dicarboxyl­ate), the Zn(II) atom is coordinated by three H(2)nba ligands and two water molecules, resulting in a distorted trigonal-bipyramidal geometry. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Supra­molecular chains are found in the crystal structure that are sustained by C—H⋯π and π–π [3.6089 (10) Å] inter­actions.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The title compound, C(21)H(21)N(3)O(7)S, contains an oxazolidinone ring and a sulfonamide group, both characteristic for biologically and pharrmaceutically active compounds. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the title compound, C(34)H(23)N(5)O(3)·0.5CH(3)OH, each pyrimid­in­one heterocycle and its adjacent benzene ring are almost coplanar, making dihedral angles of 0.69 (13) and 1.87 (13)°. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the title 1:1 silver(I) 4-carb­oxy­pyridine-3-carboxyl­ate adduct with triphenyl­phosphine, [Ag(C(7)H(4)NO(4))(C(18)H(15)P)](n), the carboxyl­ate anion bridges the phosphine-coordinated Ag atoms through its N and O atoms, generating a coordination polymer forming layers in the bc plane. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the title compound, C(10)H(12)N(6)·C(2)H(5)OH, the planarity of the heterocyclic system is slightly distorted at the triazine ring (r.m.s. deviation = 0.1191 Å), which adopts a conformation best described as inter­mediate between a flattened twisted boat and a half-boat with the tertiary Csp (3) atom at the bow. In the crystal, mol­ecules form centrosymmetric dimers connected by N⋯H—O and O⋯H—N hydrogen bonds between the amino group H atom, the ethanol solvent mol­ecule and the triazine N atom, making an R (4) (4)(12) graph-set motif. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The Cu(II) atoms are bridged by isophthalate and 3-carb­oxy­benzoate ligands, forming a chain structure along the b axis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The conformation of the triazolo-thia­diazin-3-yl fused ring system is a twisted half-chair. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the crystal, N—H⋯O hydrogen bonds form a three-dimensional network.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…H3K56me3 is a novel heterochromatin mark, since it is enriched at pericentromeres but not telomeres and is thereby similar, but not identical, to the localization of H3K9me3 and H4K20me3. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Mitogen-activated protein kinase kinase kinase3 (MAP3K3/MEKK3) was identified to be differentially expressed in esophageal squamous cell carcinoma (ESCC) using cDNA microarrays by our laboratory. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso