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  1. 2821
    por Friesen, Jon A, Rodwell, Victor W
    Publicado 2004
    “…The enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase catalyzes the conversion of HMG-CoA to mevalonate, a four-electron oxidoreduction that is the rate-limiting step in the synthesis of cholesterol and other isoprenoids. …”
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    The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases
  2. 2822
    “…Crystal structures of 14-3-3 chimeras with three different peptides provide detailed structural information on peptide-14-3-3 interactions. …”
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    Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners
  3. 2823
    “…The resultant probe enables linear 3 × 3 Mueller matrix characterization of distal tissue. …”
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    Flexible polarimetric probe for 3 × 3 Mueller matrix measurements of biological tissue
  4. 2824
    “…The three words-three shapes test is a brief bedside technique for assessment of learning and memory using verbal and non-verbal material. …”
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    Performance of elderly on the three words-three shapes test: a Brazilian study
  5. 2825
    “…In this report, we present data on the pharmacokinetics and safety of bevacizumab in children under the age of 3 years with central nervous system (CNS) malignancies. …”
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    Pharmacokinetics of Bevacizumab in Three Patients Under the Age of 3 Years with CNS Malignancies
  6. 2826
    “…Given previous evidences of sleep/circadian disturbances as well as the genetic susceptibility for BD, we decided to investigate the possible link between the PERIOD3 (Per3) circadian gene and BD. METHODS: This is a genetic association case (BD) vs. control study of the Per3 gene. …”
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    Genetic Association of the PERIOD3 (Per3) Clock Gene with Bipolar Disorder
  7. 2827
    por Cornell, Brett, Toyo-oka, Kazuhito
    Publicado 2017
    “…In particular, we focus on the 14-3-3 isoforms and their involvement in the three key stages of cortical development; neurogenesis and differentiation, neuronal migration and neuromorphogenesis and synaptogenesis.…”
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    14-3-3 Proteins in Brain Development: Neurogenesis, Neuronal Migration and Neuromorphogenesis
  8. 2828
    “…Here we demonstrate that GPCR-mediated 14-3-3 signaling is ligand-regulated and is likely to be a more general phenomenon than suggested by the previous reports of 14-3-3 involvement with a few GPCRs. …”
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    G-protein-coupled receptors mediate 14-3-3 signal transduction
  9. 2829
    “…Here we present a new multiphoton photo-excitation method, termed three-dimensional scanless holographic optogenetics with temporal focusing (3D-SHOT), which allows precise, simultaneous photo-activation of arbitrary sets of neurons anywhere within the addressable volume of a microscope. …”
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    Three-dimensional scanless holographic optogenetics with temporal focusing (3D-SHOT)
  10. 2830
    “…In the present study, we performed in vitro and in vivo investigations to elucidate the involvement of flavin-containing monooxygenase-3 (FMO3) and cytochrome P450 enzymes (CYPs) in Bu metabolic pathway. …”
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    Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway
  11. 2831
    “…We found that dihydrosanguinarine (DHS) treatment induced preadipocyte differentiation and lipid droplet accumulation in 3T3-L1 cells, but this effect is weaker than that elicited by the full PPARγ agonist troglitazone. …”
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    Dihydrosanguinarine Enhances Glucose Uptake in Mouse 3T3-L1 Cells
  12. 2832
    “…Our study thus identifies maternal H3K27me3 as the imprinting mark of Xist.…”
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    Genomic imprinting of Xist by maternal H3K27me3
  13. 2833
    “…PURPOSE: 14-3-3ζ regulates cell signaling, cell cycle progression, and apoptosis, and its overexpression is associated with disease recurrence and poor clinical outcomes in some solid tumors. …”
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    14-3-3ζ Overexpression is Associated with Poor Prognosis in Ovarian Cancer
  14. 2834
    “…The aim of this study was to assess both glycerol permeability and metabolism in undifferentiated 3T3-L1 cells (UDCs) as well as in untreated (CTL-DCs) versus lipopolysaccharide (LPS-DCs)-treated differentiated 3T3-L1 adipocytes. …”
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    Lipopolysaccharide Modifies Glycerol Permeability and Metabolism in 3T3-L1 Adipocytes
  15. 2835
    “…Chromosomal translocations that generate in-frame oncogenic gene fusions are powerful examples of success of targeted cancer therapies(1–3). We discovered FGFR3-TACC3 (F3-T3) gene fusions in 3% of human glioblastoma(4). …”
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    A metabolic function of FGFR3-TACC3 gene fusions in cancer
  16. 2836
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    Bi-exponential 3D-T1ρ mapping of whole brain at 3 T
  17. 2837
    por Wu, Ping-Li, He, Yi-Fu, Yao, Han-Hui, Hu, Bing
    Publicado 2018
    “…BACKGROUND: The aim of this study was to investigate the expression level of martrilin-3 (MATN3) in patients with gastric adenocarcinoma (GAC) and to investigate the prognostic significance of MATN3. …”
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    Martrilin-3 (MATN3) Overexpression in Gastric Adenocarcinoma and its Prognostic Significance
  18. 2838
    “…The Am(C5-BPP)(3) NMR sample is furthermore spiked with Cm(iii) and characterized by time-resolved laser fluorescence spectroscopy (TRLFS), yielding important information on the speciation of trace amounts of minor complex species.…”
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    NMR and TRLFS studies of Ln(iii) and An(iii) C5-BPP complexes
  19. 2839
    “…We identified an IPD3-like (IPD3L) gene in the M. truncatula genome. …”
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    IPD3 and IPD3L Function Redundantly in Rhizobial and Mycorrhizal Symbioses
  20. 2840
    “…When NIH3T3 cells were transfected with the plasmids having those genes with valine at codon 12, leucine at codon 61 or arginine at codon 61, transformants were efficiently produced. …”
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    Transformation of NIH3T3 Cells with Synthetic c‐Ha‐ras Genes
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