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  1. 2861
    “…Specifically, we developed a method to ectopically induce the repressive histone modification, H3K27me3 in a locus-specific manner, using a fusion construct of Oryzias latipes H3K27 methyltransferase Ezh2 (olEzh2) and dCas9 (dCas9-olEzh2). …”
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    Targeted in vivo epigenome editing of H3K27me3
  2. 2862
    “…Equine glutathione transferase A3-3 (EcaGST A3-3) belongs to the superfamily of detoxication enzymes found in all higher organisms. …”
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    Potent inhibitors of equine steroid isomerase EcaGST A3-3
  3. 2863
    por Chen, Fei, Sun, Junjie, Yan, Renpeng, Yu, Xin
    Publicado 2019
    “…The (4)F(3/2) → (4)I(9/2) laser transition of Nd(3+)-doped crystals emitting at 900 nm is a standard quasi-three-level laser system. …”
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    Reabsorption cross section of Nd(3+)-doped quasi-three-level lasers
  4. 2864
    “…Three members of the angiopoietin-like (ANGPTL) protein family-ANGPTL3, ANGPTL4 and ANGPTL8- are important regulators of plasma lipoproteins. …”
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    Angiopoietin-like protein 3 (ANGPTL3) deficiency and familial combined hypolipidemia
  5. 2865
    por Soboleva, Tatiana, Berreau, Lisa M.
    Publicado 2019
    “…In this review, we examine the various conditions under which CO is released from 3-hydroxyflavones and 3-hydroxy-4-oxoquinolines to advance the understanding of how these molecules, or derivatives thereof, may be developed as CORMs. …”
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    3-Hydroxyflavones and 3-Hydroxy-4-oxoquinolines as Carbon Monoxide-Releasing Molecules
  6. 2866
    “…PRL3-zumab binds to surface PRL3 in a manner consistent with that in classical antibody-dependent cell-mediated cytotoxicity or antibody-dependent cellular phagocytosis tumor elimination pathways, as PRL3-zumab requires an intact Fc region and host FcγII/III receptor engagement to recruit B cells, NK cells and macrophages to PRL3(+) tumor microenvironments. …”
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    PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein
  7. 2867
    por Landskron, Daniel, Böhm, Johannes
    Publicado 2017
    “…In other words, when requiring highest precision, VMF3 is to be preferable to VMF1. Aside from revising the discrete form of mapping functions, we also present a new empirical model named Global Pressure and Temperature 3 (GPT3) on a [Formula: see text] as well as a [Formula: see text] global grid, which is generally based on the same data. …”
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    VMF3/GPT3: refined discrete and empirical troposphere mapping functions
  8. 2868
    “…We studied the role of Sirtuin 3 (SIRT3) in microglial cell migration in ischemic stroke. …”
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    Sirtuin 3 promotes microglia migration by upregulating CX3CR1
  9. 2869
    “…Overall, this carboallylation reaction gives a new route to the synthesis of 3,3-disubstituted heterocycles.…”
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    Synthesis of 3,3-Disubstituted Heterocycles by Pd-Catalyzed Arylallylation of Unactivated Alkenes
  10. 2870
    “…[Image: see text] In the present work, we selected hexamethylcucurbit[3,3]uril (Me(6)Q[3,3]) as a building block and obtained two Me(6)Q[3,3]-based porous supramolecular assemblies from neutral water (A) and aqueous HCl solutions (B), respectively. …”
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    Hexamethylcucurbit[3,3]uril-Based Porous Supramolecular Assemblies and Their Adsorption Properties
  11. 2871
    “…We tested for the first time the potential of glyphosate, 2, 4-dichlorophenoxyacetic acid, dicamba, mesotrione, isoxaflutole, and quizalofop-p-ethyl (QpE) to induce lipid accumulation in murine 3T3-L1 adipocytes. Only QpE caused a dose-dependent statistically significant triglyceride accumulation from a concentration of 5 up to 100 µM. …”
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    Quizalofop-p-Ethyl Induces Adipogenesis in 3T3-L1 Adipocytes
  12. 2872
    “…Porcine circovirus 3 (PCV3) is a newly described member of the virus family Circoviridae. …”
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    Transmission of Porcine Circovirus 3 (PCV3) by Xenotransplantation of Pig Hearts into Baboons
  13. 2873
    “…Some GPCRs associate with 14-3-3 proteins at the cell membrane and agonist treatments result in disrupted GPCR/14-3-3 interaction signals. …”
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    14-3-3 signal adaptor and scaffold proteins mediate GPCR trafficking
  14. 2874
    “…5’ ends are important for determining the fate of RNA molecules. BCDIN3D is an RNA phospho-methyltransferase that methylates the 5’ monophosphate of specific RNAs. …”
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    BCDIN3D regulates tRNA(His) 3’ fragment processing
  15. 2875
    “…The aim of the study was to explore the possible role of Trefoil Factor Family peptide 3 (TFF3) for skeletal repair. The expression of TFF3 was analyzed in human joint tissues as well as in a murine bone fracture model. …”
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    Trefoil Factor 3 (TFF3) Is Involved in Cell Migration for Skeletal Repair
  16. 2876
    “…Taken together, our findings suggest that miR-152 could suppress 3T3-L1 preadipocyte proliferation, whereas it could promote 3T3-L1 preadipocyte differentiation by negatively regulating LPL. …”
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    Mir-152 Regulates 3T3-L1 Preadipocyte Proliferation and Differentiation
  17. 2877
    “…Regulatory 14-3-3 proteins interact with a plethora of phosphorylated partner proteins, however 14-3-3 complexes feature intrinsically disordered regions and often a transient type of interactions making structural studies difficult. …”
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    Concatenation of 14-3-3 with partner phosphoproteins as a tool to study their interaction
  18. 2878
    “…This three-dimensional analysis evaluated the response to static forces on the three models. …”
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    A Comparative 3D Finite Element Computational Study of Three Connections
  19. 2879
    “…Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that is activated by interleukin (IL)-6 and IL-10 that generate nearly opposing responses. …”
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    Increased expression of STAT3 and SOCS3 in placenta from hyperglycemic rats
  20. 2880
    “…In order to boost the electromechanical coupling factor and decrease the characteristic impedance, a 1-3 piezoelectric composite with a 3-tier polymer structure was designed and fabricated, in which epoxy resin constitutes the middle layer and silicone rubber is used to clamp the epoxy. …”
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    Characterization of 1-3 Piezoelectric Composite with a 3-Tier Polymer Structure
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