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  1. 3281
    “…Human chymotrypsin-like elastases 3A and 3B (CELA3A and CELA3B) are the products of gene duplication and share 92% identity in their primary structure. …”
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    Genetic Analysis of Human Chymotrypsin-Like Elastases 3A and 3B (CELA3A and CELA3B) to Assess the Role of Complex Formation between Proelastases and Procarboxypeptidases in Chronic Pancreatitis
  2. 3282
    “…BACKGROUND: Two new subclades of influenza A(H3N2) viruses became prominent during the 2014‐2015 Northern Hemisphere influenza season. …”
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    The characteristics and antigenic properties of recently emerged subclade 3C.3a and 3C.2a human influenza A(H3N2) viruses passaged in MDCK cells
  3. 3283
    “…Objective: We aimed to investigate the therapeutic use of RA as an anti-obesity agent by measuring its effects on adipogenesis, lipolysis, and messenger RNA (mRNA) expression of major adipokines in 3T3-L1 adipocytes; and its effects on lipopolysaccharide (LPS)-induced tumor necrosis factor-α (TNF-α) secretion in macrophages and inflammatory mediators in 3T3-L1 adipocytes incubated with macrophage-conditioned medium (MCM). …”
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    Rosmarinic acid suppresses adipogenesis, lipolysis in 3T3-L1 adipocytes, lipopolysaccharide-stimulated tumor necrosis factor-α secretion in macrophages, and inflammatory mediators in 3T3-L1 adipocytes
  4. 3284
    “…These included mannose(6)-N-acetyl-glucosamine(2) (P=0.044), mannose(9)-N-acetyl-glucosamine(2) (Ρ=0.030) and NeuAc3H3N3M3N2F (Ρ=0.002). These three glycan structures may therefore be associated with tumor progression in CCA and may be useful for its diagnosis.…”
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    Increased expression of the high-mannose M6N2 and NeuAc3H3N3M3N2F tri-antennary N-glycans in cholangiocarcinoma
  5. 3285
    “…Heparan sulfate 3-O-sulfotransferases (HS3STs) catalyze the maturation step of heparan sulfate (HS) 3-O-sulfation. …”
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    The Pro-Tumoral Activity of Heparan Sulfate 3-O-Sulfotransferase 3B (HS3ST3B) in Breast Cancer MDA-MB-231 Cells Is Dependent on the Expression of Neuropilin-1
  6. 3286
    “…Using a common 1-(1-phenylethenyl)-1,2,3,4-tetrahydroisoquinoline precursor to the required ylide or N-oxide intermediate, the Stevens [2,3] and analogous Meisenheimer [2,3] sigmatropic rearrangements have been applied to afford concise syntheses of phenyl -substituted representatives of each of the reduced 1H-3-benzazonine and 4,3-benzoxazonine systems, respectively. …”
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    Synthesis and X-ray Structural Studies of a Substituted 2,3,4,5-Tetrahydro-1H-3-benzazonine and a 1,2,3,5-Tetrahydro-4,3-benzoxazonine
  7. 3287
    “…The results of the study suggest that 3-(quinoxaline-3-yl) prop-2-ynyl methanosulphate and 3-(quinoxaline-3-yl) prop-2-yn-1-ol induce apoptotic cell death in A549 lung cancer cells.…”
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    Induction of Cell Death in Human A549 Cells Using 3-(Quinoxaline-3-yl) Prop-2-ynyl Methanosulphonate and 3-(Quinoxaline-3-yl) Prop-2-yn-1-ol
  8. 3288
    “…The XRD pattern revealed a polycrystalline nature with the hexagonal structure of the La(2)O(3) NPs. The synthesized undoped and doped La(2)O(3) NPs were also employed as catalysts for the reduction of 4-nitrophenol, it shows that the doped (Sm(3+), Gd(3+) and Hf(3+)) La(2)O(3) NPs provided better catalytic activity than the undoped La(2)O(3) NPs. …”
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    Facile synthesis, characterization and enhanced catalytic reduction of 4-nitrophenol using NaBH(4) by undoped and Sm(3+), Gd(3+), Hf(3+) doped La(2)O(3) nanoparticles
  9. 3289
    por Kumar, S. Anil, Bhaskar, B.L.
    Publicado 2019
    “…Detection and qualification of unknown impurities during commercial drug synthesis have been mandated by the regulatory authorities. 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo [d]azepin-2-one) in short IVA-9, is one such process-related impurity formed during the synthesis of cardiotonic drug Ivabradine. …”
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    Computational and spectral studies of 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one)
  10. 3290
    “…The present study reports the modulation of MI transitions in [10 nm-NdNiO(3)/t-LaNiO(3)/10 nm-NdNiO(3)/SrTiO(3) (100)] trilayers (t = 5, 7, 10, and 20 nm) via the control of the LaNiO(3) thickness. …”
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    Modulation of metal-insulator transitions of NdNiO(3)/LaNiO(3)/NdNiO(3) trilayers via thickness control of the LaNiO(3) layer
  11. 3291
    “…The importance of germline-inherited posttranslational histone modifications on priming early mammalian development is just emerging(1–4). Histone H3 lysine 9 (H3K9) trimethylation is associated with heterochromatin and gene repression during cell-fate change(5), while histone H3 lysine 4 (H3K4) trimethylation marks active gene promoters(6). …”
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    KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
  12. 3292
    “…To gain a better understanding and a more decisive precursor for TNBC, two major histone modifications, an activating modification H3K4me3 and a repressive modification H3K27me3, were analyzed using data from normal breast cell lines against TNBC cell lines. …”
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    Analysis of opposing histone modifications H3K4me3 and H3K27me3 reveals candidate diagnostic biomarkers for TNBC and gene set prediction combination
  13. 3293
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    Retracted: DNA Binding and Photocleavage Studies of Cobalt(III) Polypyridine Complexes: [Co(en)(2)PIP](3+), [Co(en)(2)IP](3+), and [Co(en)(2)phen-dione](3+)
  14. 3294
    por Wang, Hongli, Zeng, Kaiyang
    Publicado 2021
    “…The effect of relative humidity on the domain structure imaging and polarization switching process of Pb(Zn(1/3)Nb(2/3))O(3)-x%PbTiO(3) (PZN-x%PT) ferroelectric single crystals has been investigated by means of the piezoresponse force microscopy (PFM) and piezoresponse force spectroscopy (PFS) techniques. …”
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    Humidity Effects on Domain Structure and Polarization Switching of Pb(Zn(1/3)Nb(2/3))O(3)-x%PbTiO(3) (PZN-x%PT) Single Crystals
  15. 3295
    “…Gd and Yb elements have high chemical stability, which can stabilize the solid solution in ZrO(2). Gd(2)O(3) and Yb(2)O(3) have high melting points, and good oxidation resistance in extreme environments, stable chemical properties. …”
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    Effect of Gd(2)O(3) Addition on the Microstructure and Properties of Gd(2)O(3)-Yb(2)O(3)-Y(2)O(3)-ZrO(2) (GYYZO) Ceramics
  16. 3296
    “…Here, we characterize the localization, the biogenesis, and the function of an atypical heterochromatin, which is simultaneously enriched in the typical H3K9me3 mark and in H3K36me3, a histone mark usually associated with gene expression. …”
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    SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers
  17. 3297
    “…Pediatric high-grade gliomas (pHGG) are among the most lethal of all human cancers. Histone H3.3 G34R/V mutations are an early event in these tumors and show reduced H3.3 K36 trimethylation; implicating epigenetic dysregulation in tumorigenesis. …”
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    HGG-30. H3.3 G34R/V mutations disrupt H3.3 mitotic phosphorylation leading to high-grade glioma formation through the induction of chromosomal instability
  18. 3298
    “…This study retrospectively characterized Neu3 and ST3Gal3 expression by immunohistochemistry in 71 paraffin-embedded GC tissue specimens and analyzed the relationship between their expression and the clinicopathological parameters. …”
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    α2,3 sialic acid processing enzymes expression in gastric cancer tissues reveals that ST3Gal3 but not Neu3 are associated with Lauren's classification, angiolymphatic invasion and histological grade
  19. 3299
    “…We recently demonstrated the prognostic relevance of EMT-related (epithelial-mesenchymal transition) genes in stage II/III CRC. As EMT is a major step in CRC progression, we now aimed to analyse the prognostic relevance of EMT-related genes in stage IV CRC using the study cohort of the FIRE-3 trial, an open-label multi-centre randomised controlled phase III trial of patients with metastatic CRC. …”
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    EMT-Related Genes Have No Prognostic Relevance in Metastatic Colorectal Cancer as Opposed to Stage II/III: Analysis of the Randomised, Phase III Trial FIRE-3 (AIO KRK 0306; FIRE-3)
  20. 3300
    “…To combat these infections, the search for new therapeutic agents is in high demand. A series of new 3-(2-(3-(substituted benzyloxy)oxetan-3-yl)-3-fluorophenoxy)-8-fluoro-2-methylquinoline (9a–i) derivatives have been synthesized. …”
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    Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3-(2-(3-(Substituted benzyloxy)oxetan-3-yl)-3-fluorophenoxy)-8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents
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