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  1. 3441
    “…Methods and Results: In this study, we discovered a previously unexplored regulation mechanism for histone PTMs by targeting transcription regulation factor 14-3-3ζ. Mechanistic studies revealed 14-3-3ζ dimerization as a key prerequisite, which could be dynamically induced via an allosteric effect. …”
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    Allosteric regulation of protein 14-3-3ζ scaffold by small-molecule editing modulates histone H3 post-translational modifications
  2. 3442
    “…Herein, we reported that Notch3 promotes mouse 3T3‐L1 pre‐adipocytes differentiation by performing the integrative transcriptome and TMT‐based proteomic analyses. …”
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    Notch3 promotes 3T3‐L1 pre‐adipocytes differentiation by up‐regulating the expression of LARS to activate the mTOR pathway
  3. 3443
    “…This study employs the deposition of an electron transport layer of C(60) and an Ag electrode on CH(3)NH(3)PbBr(3) perovskite crystals to complete a photodetector structure, which exhibits a metal–semiconductor–metal (MSM) type structure. …”
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    Study of Metal–Semiconductor–Metal CH(3)NH(3)PbBr(3) Perovskite Photodetectors Prepared by Inverse Temperature Crystallization Method
  4. 3444
    “…In this work, we report on the fabrication of depressed-cladding waveguide 2D 2 × 2, 1 × 2 and 3D 3 × 3 directional couplers in Tm [Formula: see text]:YAG crystal by femtosecond laser writing. …”
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    Femtosecond Laser Written Depressed-Cladding Waveguide 2 × 2, 1 × 2 and 3 × 3 Directional Couplers in Tm(3+):YAG Crystal
  5. 3445
    “…The genes A6X20_40975 and A6X20_41030 in strain BLY3-8 were predicted to encode the transcriptional activator and apparatus of the type III secretion system (T3SS) (the proteins TtsI and RhcJ), respectively. …”
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    Mutants Disrupted in the Type III Secretion System of Bradyrhizobium elkanii BLY3-8 Overcame Nodulation Restriction by Rj(3)-genotype Soybean
  6. 3446
    “…This paper's contribution lies in achieving a step-by-step procedure of scanning any three-dimensional object as this helps in understanding the 3D scanning hardware and support software. …”
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    3D scanning of a carburetor body using COMET 3D scanner supported by COLIN 3D software: Issues and solutions
  7. 3447
    “…The present study identified miR-27a-3p as a critical suppressor of osteoblastogenesis. …”
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    miR-27a-3p negatively regulates osteogenic differentiation of MC3T3-E1 preosteoblasts by targeting osterix
  8. 3448
    “…BACKGROUND: Clinical trials have been conducted to clarify the beneficial effects of VD3 (1α,25-dihydroxy vitamin D3, also known as calcitriol) treatment in prostate cancer. …”
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    Molecular evidence of IGFBP-3 dependent and independent VD3 action and its nonlinear response on IGFBP-3 induction in prostate cancer cells
  9. 3449
    “…Replication-dependent canonical histone messenger RNAs (mRNAs) do not terminate with a poly(A) tail at the 3′ end. We previously demonstrated that exposure to arsenic, an environmental carcinogen, induces polyadenylation of canonical histone H3.1 mRNA, causing transformation of human cells in vitro. …”
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    Polyadenylation of Histone H3.1 mRNA Promotes Cell Transformation by Displacing H3.3 from Gene Regulatory Elements
  10. 3450
    “…2D and 3D cultures of 3T3-L1 cells were employed in a study of the effects of Omidenepag (OMD), interacting with a non-prostanoid EP2 receptor, on adipogenesis. …”
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    Omidenepag, a non-prostanoid EP2 receptor agonist, induces enlargement of the 3D organoid of 3T3-L1 cells
  11. 3451
    “…In yeast, NuA3 histone acetyltransferase (NuA3 HAT) promotes acetylation of histone H3 lysine 14 (H3K14) and transcription of a subset of genes through interaction between the Yng1 plant homeodomain (PHD) finger and H3K4me3. …”
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    NuA3 HAT antagonizes the Rpd3S and Rpd3L HDACs to optimize mRNA and lncRNA expression dynamics
  12. 3452
    “…In this work, we propose CH(3)NH(3)PbI(3) (MAPI) perovskite slab models whose energy levels, free of quantum confinement, explicitly consider the spin–orbit coupling and thermal motion. …”
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    Methodological Issues in First-Principle Calculations of CH(3)NH(3)PbI(3) Perovskite Surfaces: Quantum Confinement and Thermal Motion
  13. 3453
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    Faraday Rotation of Dy(2)O(3), CeF(3) and Y(3)Fe(5)O(12) at the Mid-Infrared Wavelengths
  14. 3454
    “…The new series of 3-(2-chlorophenyl)- and 3-(3-chlorophenyl)-pyrrolidine-2,5-dione-acetamide derivatives as potential anticonvulsant and analgesic agents was synthesized. …”
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    Synthesis, Anticonvulsant, and Antinociceptive Activity of New 3-(2-Chlorophenyl)- and 3-(3-Chlorophenyl)-2,5-dioxo-pyrrolidin-1-yl-acetamides
  15. 3455
    por Winston, Dennis S., Boehr, David D.
    Publicado 2021
    “…Expansion of the conformational ensemble available to 3CD may allow it to perform additional functions not observed in 3C and 3D alone despite having nearly identical lowest-energy structures.…”
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    The Picornavirus Precursor 3CD Has Different Conformational Dynamics Compared to 3C(pro) and 3D(pol) in Functionally Relevant Regions
  16. 3456
    “…Second, androgens can also influence gene expression by decreasing the tri-methyl mark on lysine 27 of histone3 (H3K27me3), a gene silencing epigenetic mark. …”
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    Androgens regulate ovarian gene expression by balancing Ezh2-Jmjd3 mediated H3K27me3 dynamics
  17. 3457
    “…Binding domain mapping showed that the CC1 domain of VP3 and the residue lysine-155 of tumor necrosis factor receptor-associated factor 3 (TRAF3) are essential for the interaction. …”
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    Inhibition of Antiviral Innate Immunity by Avibirnavirus VP3 via Blocking TBK1-TRAF3 Complex Formation and IRF3 Activation
  18. 3458
    “…The aim of this study was to evaluate the precision of extraoral digitalization of three types of photosensitive resin polymers used for 3D printing with the aid of a digital extraoral optical scanner. …”
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    Accuracy of Three-Dimensional (3D) Printed Dental Digital Models Generated with Three Types of Resin Polymers by Extra-Oral Optical Scanning
  19. 3459
    “…SF3B3 was identified firstly as a negative autophagic regulator, and siRNA/shRNA-SF3B3 were shown to induce autophagy-associated cell death in in vitro and in vivo breast cancer models. …”
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    Multi-omics approaches identify SF3B3 and SIRT3 as candidate autophagic regulators and druggable targets in invasive breast carcinoma
  20. 3460
    “…This paper describes the reaction of Al(OR(F))(3)*PhF (R(F) = C(CF(3))(3)) with silica partially dehydroxylated at 700 °C (SiO(2-700)) to form the bridging silanol [triple bond, length as m-dash]Si–OH⋯Al(OR(F))(3) (1). …”
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    Al(OR(F))(3) (R(F) = C(CF(3))(3)) activated silica: a well-defined weakly coordinating surface anion
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