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  1. 3741
    por Ren, Dong-mei
    Publicado 2012
    “…In the title compound, C(10)H(9)Cl(2)NO(3), the dihedral angle between the benzene ring and the plane of the nitro group is 39.1 (1)°, while that between the benzene ring and the plane through the three C and two Cl atoms of the dichloro­all­yloxy unit is 40.1 (1)°. …”
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    1-(3,3-Dichloro­all­yloxy)-4-methyl-2-nitro­benzene
  2. 3742
    “…In the title compound, C(11)H(9)N(3)O, the quinazoline unit is almost planar, with a mean deviation of 0.006 (1) Å from the least-squares plane defined by the ten constituent atoms. …”
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    3,8-Dimethyl-4-oxo-3,4-dihydro­quinazoline-6-carbonitrile
  3. 3743
    “…In the title compound, C(13)H(10)FN(3)O(3), the dihedral angle between the fluoro­phenyl and nitro­phenyl ring planes is 6.51 (9)°. …”
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    1-(3-Fluoro­phen­yl)-3-(4-nitro­phen­yl)urea
  4. 3744
    “…Human organic cation transporter 3 (OCT3, SLC22A3) mediates the uptake of many important endogenous amines and basic drugs in a variety of tissues. …”
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    Genetic and Epigenetic Regulation of the Organic Cation Transporter 3, SLC22A3
  5. 3745
    “…We recently showed that 3β-acetyl tormentic acid (3ATA) had no effect on P-gp/ABCB1 activity. …”
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    Effects of 3β-Acethyl Tormentic Acid (3ATA) on ABCC Proteins Activity
  6. 3746
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    1-Phenyl-3H-2,3-benzodiazepin-4(5H)-one
  7. 3747
    “…However, it remains unclear how TRB3 contributes to the process. We recently demonstrated that TRB3 was cleaved by caspase-3 (CASP3) in vitro and also in apoptosis-induced cells. …”
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    Stress-Inducible Caspase Substrate TRB3 Promotes Nuclear Translocation of Procaspase-3
  8. 3748
    “…The dihedral angles between the tetra­zole ring and its three attached benzene rings in the four independent cations are: 12.9 (4), 67.0 (4), 48.1 (4); 20.8 (4), 51.1 (4), 62.3 (4); 11.4 (4), 52.3 (4), 47.3 (4) and 6.0 (4), 85.7 (4), 43.5 (4)°. …”
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    2,3,5-Triphenyl-2H-tetra­zol-3-ium iodide
  9. 3749
    “…Autophagy is a tightly regulated lysosomal self-digestion process that can both promote and impede tumorigenesis. Here, we utilize a three-dimensional (3D) culture model to address how interactions between autophagy and the PI3K/Akt/mTOR pathway impact the malignant behavior of cells carrying a tumor-derived, activating mutation in PI3K (PI3K-H1047R). …”
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    Autophagy Restricts Proliferation Driven By Oncogenic Phosphatidylinositol 3-Kinase in Three-Dimensional Culture
  10. 3750
    “…The present report describes nonsurgical endodontic treatment of three mandibular second premolars with three canals. …”
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    Mandibular Second Premolars with Three Root Canals: A Review and 3 Case Reports
  11. 3751
    “…Suppressor of cytokine signaling 3 (SOCS3) is a major negative regulator of both leptin and insulin signaling, thereby implicating SOCS3 in the pathogenesis of obesity and associated metabolic abnormalities. …”
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    Regulation of Insulin and Leptin Signaling by Muscle Suppressor of Cytokine Signaling 3 (SOCS3)
  12. 3752
    “…The engagement of Toll-like receptor 3 (TLR3) leads to the oligomerization of the adaptor TICAM-1 (TRIF), which can induces either of three acute cellular responses, namely, cell survival coupled to Type I interferon production, or cell death, via apoptosis or necrosis. …”
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    TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis
  13. 3753
    “…In this study some new 2,3-disubstituted-4(3H)quinqzolinone derivatives were synthesized from anthranilic acid in six steps by introducing a new chiral center to the aliphatic side chain of the quinazolinone. …”
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    Synthesis of some new 2,3-disubstituted-4(3H)quinazolinone derivatives
  14. 3754
    por Sarkar, Anita, Pérez, Serge
    Publicado 2012
    “…The knowledge of polysaccharide three-dimensional (3D) structure is important in studying carbohydrate-mediated host-pathogen interactions, interactions with other bio-macromolecules, drug design and vaccine development as well as material science applications or production of bio-ethanol. …”
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    PolySac3DB: an annotated data base of 3 dimensional structures of polysaccharides
  15. 3755
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    A TRPC3 blocker, Pyr3, prevents stent-induced arterial remodeling
  16. 3756
    “…Lysyl hydroxylase 3 (LH3) has lysyl hydroxylase, galactosyltransferase, and glucosyltransferase activities, which are sequentially required for the formation of glucosylgalactosyl hydroxylysines in collagens. …”
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    The Activities of Lysyl Hydroxylase 3 (LH3) Regulate the Amount and Oligomerization Status of Adiponectin
  17. 3757
    “…In the title compound, C(11)H(10)O(3), the 1-indanone unit is essentially planar (r.m.s. deviation = 0.036 Å). …”
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    3-Oxo-2,3-dihydro-1H-inden-4-yl acetate
  18. 3758
    “…The mean plane of the allyl group is roughly perpendicular to the mean plane of the 1,3-benzimidazol-2(3H)-one system, making a dihedral angle of 86.1 (2)°. …”
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    1-Allyl-1H-1,3-benzimidazol-2(3H)-one
  19. 3759
    “…Objectives: To investigate cognitive components and mechanisms of learning and memory in primary progressive aphasia (PPA) using a simple clinical measure, the Three Words Three Shapes Test (3W3S). Background: PPA patients can complain of memory loss and may perform poorly in standard tests of memory. …”
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    Verbal and Nonverbal Memory in Primary Progressive Aphasia: The Three Words-Three Shapes Test
  20. 3760
    “…METHODOLOGY/PRINCIPAL FINDINGS: Induced cells were identified as adipocytes based on the following three characteristics: (1) Accumulation of triglyceride droplets as demonstrated by oil red O stain. (2) Transport rate of 2-deoxyglucose increased after insulin stimulation. (3) Expression of fat specific genes such as Fabp4 (aP2), Slc2a4 (Glut4) and Pparg (PPARγ). …”
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    Prolonged Induction Activates Cebpα Independent Adipogenesis in NIH/3T3 Cells
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