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3941por Murer, Anita, McHugh, Donal, Caduff, Nicole, Kalchschmidt, Jens, Barros, Mario, Zbinden, Andrea, Capaul, Riccarda, Niedobitek, Gerald, Allday, Martin, Chijioke, Obinna, Münz, Christian“…The EBV oncoproteins nuclear antigen 3A (EBNA3A) and 3C (EBNA3C) are required for B cell transformation in vitro and are expressed in EBV associated immunoblastic lymphomas in vivo. …”
Publicado 2018
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3942“…The title compound, (systematic name: N,N′-dibenzyl-3,3′-dimethoxy-1,1′-biphenyl-4,4′-diamine), C(28)H(28)N(2)O(2), was synthesized by the reduction of a Schiff base prepared via a condensation reaction between o-dianisidine and benzaldehyde under acidic conditions. …”
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3943por Liu, Wei, Löwenheim, Hubert, Santi, Peter A., Glueckert, Rudolf, Schrott-Fischer, Annelies, Rask-Andersen, Helge“…TMPRSS3 (Trans-membrane Serine Protease 3) is a type II trans-membrane serine protease that has proteolytic activity essential for hearing. …”
Publicado 2018
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3944“…AIM: Variants of TIM-3/HAVCR2 3′UTR miRNA binding sites are significantly associated with cancer; however, roles in post-transcriptional regulation have not been elucidated. …”
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3945por Rabouw, Freddy T., Prins, P. Tim, Villanueva-Delgado, Pedro, Castelijns, Marieke, Geitenbeek, Robin G., Meijerink, Andries“…Here we study the excited-state dynamics of the workhorse UC material β-NaYF(4) co-doped with Yb(3+) and Er(3+). For each of the energy levels involved in infrared-to-visible UC, we measure and model the competition between spontaneous emission, energy transfer between lanthanide ions, and other decay processes. …”
Publicado 2018
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3946“…Self-standing Bi(2)Te(3) networks of interconnected nanowires were fabricated in three-dimensional porous anodic alumina templates (3D–AAO) with a porous structure spreading in all three spatial dimensions. …”
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3947por Song, Min Seok, Park, Su Min, Park, Jeong Seok, Byun, Jin Ho, Jin, Hee Jung, Seo, Seung Hyun, Ryu, Pan Dong, Lee, So Yeong“…Voltage-gated potassium (Kv) channels, including Kv3.1 and Kv3.4, are known as oxygen sensors, and their function in hypoxia has been well investigated. …”
Publicado 2018
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3948por Wakae, Kousho, Nishiyama, Tomoaki, Kondo, Satoru, Izuka, Takashi, Que, Lusheng, Chen, Cong, Kase, Kina, Kitamura, Kouichi, Mohiuddin, Md, Wang, Zhe, Ahasan, Md Monjurul, Nakamura, Mitsuhiro, Fujiwara, Hiroshi, Yoshizaki, Tomokazu, Hosomochi, Kazuyoshi, Tajima, Atsushi, Nakahara, Tomomi, Kiyono, Tohru, Muramatsu, Masamichi“…In vitro, we found that APOBEC3A (A3A) and 3B (A3B) expression, as well as mtDNA hypermutation, were induced in a cervical dysplastic cell line W12 when cultured in a differentiating condition. …”
Publicado 2018
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3949“…Ectonucleotide phosphodiesterase/pyrophosphatase-3 (NPP3) is a membrane-bound glycoprotein that regulates extracellular levels of nucleotides. …”
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3950por Winkelhaus, Daniel, Holthausen, Michael H., Dobrovetsky, Roman, Stephan, Douglas W.“…The cationic N(3)-species [(p-HC(6)F(4))(3)PN(3)](+) (1) featuring a perfluoro-arene phosphonium group serves as a N(3)(+)-source in stoichiometric reactions with several Lewis bases (L) allowing for the stepwise formation of [(L)N(3)](+) and [(L)(2)N(3)](+) cations (L = phosphine, carbene) with liberation of (p-HC(6)F(4))(3)P. …”
Publicado 2015
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3951“…GAS could also reduce reactive oxygen species (ROS) production, inhibit mitochondrial permeability transition pore (mPTP) opening, alter the maintenance of the mitochondrial membrane potential (∆Ψm), decrease the activation of caspase-3, and finally restrain cell apoptosis. Downregulating 14-3-3η levels by transfection with siRNA14-3-3η clearly attenuated the protective effect of GAS on cardiomyocytes in A/R injury.…”
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3952por Park, Eunkuk, Kim, Jeonghyun, Yeo, Subin, Kim, Gijeong, Ko, Eun-Hee, Lee, Sang Woo, Li, Wan Yi, Choi, Chun Whan, Jeong, Seon-Yong“…Loganic acid treatment significantly decreased the adipocyte differentiation of 3T3-L1 preadipocytes in a dose-dependent manner. …”
Publicado 2018
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3953“…The filtration efficiencies of triple modal tungsten oxide (WO(x)) nanoparticles were experimentally determined at three different concentrations for the size range of 0.82–3.3 nm in diameter. …”
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3954por Yu, Xiaoyan, Teng, Xiao-Lu, Wang, Feixiang, Zheng, Yuhan, Qu, Guojun, Zhou, Yan, Hu, Zhilin, Wu, Zhongqiu, Chang, Yuzhou, Chen, Lei, Li, Hua-Bing, Su, Bing, Lu, Liming, Liu, Zhiduo, Sun, Shao-Cong, Zou, Qiang“…Here, we report that lysosomal TRAF3IP3 acts as a pivotal regulator in the maintenance of T reg cell metabolic fitness. …”
Publicado 2018
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3955“…In this data article we attempt to shed some light on the 3D structure, providing useful details about the crystallization process of the 14-3-3ζ dimer in complex with the 13-mer SOS1pS(1161). …”
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3956por Karlberg, Tobias, Hornyak, Peter, Pinto, Ana Filipa, Milanova, Stefina, Ebrahimi, Mahsa, Lindberg, Mikael, Püllen, Nikolai, Nordström, Axel, Löverli, Elinor, Caraballo, Rémi, Wong, Emily V., Näreoja, Katja, Thorsell, Ann-Gerd, Elofsson, Mikael, De La Cruz, Enrique M., Björkegren, Camilla, Schüler, Herwig“…ADP-ribosyltransferase activities of Pseudomonas exotoxin-S and -T depend on 14-3-3 proteins inside the host cell. By binding in the 14-3-3 phosphopeptide binding groove, an amphipathic C-terminal helix of ExoS and ExoT has been thought to be crucial for their activation. …”
Publicado 2018
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3957por Liu, Jinyi, Zheng, Xiangjin, Pang, Xiaocong, Li, Li, Wang, Jinhua, Yang, Cui, Du, Guanhua“…Disialoganglioside with three glycosyl groups (GD3) and disialoganglioside with two glycosyl groups (GD2) are markedly increased in pathological conditions such as cancers and neurodegenerative diseases. …”
Publicado 2018
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3958por Bento-Abreu, Andre, Jager, Gunilla, Swinnen, Bart, Rué, Laura, Hendrickx, Stijn, Jones, Ashley, Staats, Kim A, Taes, Ines, Eykens, Caroline, Nonneman, Annelies, Nuyts, Rik, Timmers, Mieke, Silva, Lara, Chariot, Alain, Nguyen, Laurent, Ravits, John, Lemmens, Robin, Cabooter, Deirdre, Van Den Bosch, Ludo, Van Damme, Philip, Al-Chalabi, Ammar, Bystrom, Anders, Robberecht, Wim“…Depletion of ELP3 in vitro reduced the modified tRNA wobble uridine mcm(5)s(2)U and increased abundance of insoluble mutant SOD1, which was reverted by exogenous ELP3 expression. …”
Publicado 2018
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3959“…Genetic and clinical studies have demonstrated that loss-of-function variants in the angiopoietin-like 3 (ANGPTL3) gene are associated with decreased plasma levels of triglycerides (TGs), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C), which leads to a significant reduction in cardiovascular risk. …”
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3960“…FGFR3-TACC3 retains the entire extracellular domain and most of the kinase domain of FGFR3, with its C-terminal domain fused to TACC3. …”
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