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  1. 4041
    “…DUSP3 interacted with the C-terminal domain of STAT3 and dephosphorylated p-Y705 of STAT3. …”
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    Regulation of signal transducer and activator of transcription 3 activation by dual-specificity phosphatase 3
  2. 4042
    “…3,3′-Diindolylmethane (DIM) is a naturally derived chemopreventive compound. …”
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    Chemopreventive Agent 3,3′-Diindolylmethane Inhibits MDM2 in Colorectal Cancer Cells
  3. 4043
    “…Here, we investigated whether the Smad3 inhibitor SIS3 can ameliorate damage to injured podocytes. …”
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    Puromycin aminonucleoside‐induced podocyte injury is ameliorated by the Smad3 inhibitor SIS3
  4. 4044
    “…We determined the cryo–electron microscopy structures of human connexin 31.3 (Cx31.3)/GJC3 hemichannels in the presence and absence of calcium ions and with a hearing-loss mutation R15G at 2.3-, 2.5-, and 2.6-Å resolutions, respectively. …”
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    Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel
  5. 4045
    por Ku, Hui-Chen, Cheng, Ching-Feng
    Publicado 2020
    “…Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that plays vital roles in modulating metabolism, immunity, and oncogenesis. …”
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    Master Regulator Activating Transcription Factor 3 (ATF3) in Metabolic Homeostasis and Cancer
  6. 4046
    por Gao, Shuang, Cui, Zhao, Zhao, Ming-hui
    Publicado 2020
    “…The pathogenesis of some kidney diseases is closely associated with complement activation, where the C3a/C3a receptor (C3aR) might play a crucial role. …”
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    The Complement C3a and C3a Receptor Pathway in Kidney Diseases
  7. 4047
    “…We discovered a unique expression pattern of two histone methyltransferases Suv39h1 and Suv39h2 during 3T3-L1 adipogenesis, both of which preferentially catalyse the formation of H3K9 dimethylation (H3K9me2) and further H3K9 trimethylation (H3K9me3), a transcriptional repressive mark. …”
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    The histone methyltransferase Suv39h regulates 3T3-L1 adipogenesis
  8. 4048
    “…CONCLUSION: No evidence of hemolytic anemia associated with ceftobiprole was observed in either adults or children across several indications in this analysis of three large Phase 3 trials.…”
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    No Evidence for Ceftobiprole-Induced Immune Hemolytic Anemia in Three Phase 3 Clinical Trials
  9. 4049
    por Zhang, Yi, Wang, Jun, Xiao, Yi
    Publicado 2020
    “…The template-based methods usually can give more accurate 3D structures due to the use of native 3D templates, but they cannot work if the 3D templates are not available. …”
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    3dRNA: Building RNA 3D structure with improved template library
  10. 4050
    “…Hence, in this study, we developed a biosilica-based syringe filtration system for the efficient separation of biomolecules from cancer samples using amine-modified diatomaceous earth (AD) with dimethyl 3,3′-dithiobispropionimidate (DTBP). The syringe filter can be an efficient and rapid tool for use in various procedures without complex instruments. …”
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    Dimethyl 3,3′-dithiobispropionimidate-functionalized diatomaceous earth particles for efficient biomolecule separation
  11. 4051
    “…In contrast, genetic disruption of RGN inhibited adipogenic stimulation‐induced differentiation of 3T3‐L1 cells. Furthermore, RGN overexpression in differentiated 3T3‐L1 adipocytes blocked inflammatory crosstalk between 3T3‐L1 adipocytes and RAW264.7 macrophages in a transwell coculture system. …”
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    Regucalcin enhances adipocyte differentiation and attenuates inflammation in 3T3‐L1 cells
  12. 4052
    “…The phase mask encodes the 3D fluorescence intensity into a single 2D measurement, and the 3D volume is recovered by solving a sparsity-constrained inverse problem. …”
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    Miniscope3D: optimized single-shot miniature 3D fluorescence microscopy
  13. 4053
    “…Cul3 is a component of E3-ubiquitin ligase complexes that target substrates for ubiquitin-dependent proteasomal degradation. …”
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    The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription
  14. 4054
    por Dharmshaktu, Ganesh S.
    Publicado 2020
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    Three important events to reaffirm three important elements in global COVID-19 management
  15. 4055
    “…After sternal tumor resection, reconstruction of chest wall defects is still a challenging part of thoracic surgery. Three‐dimensional (3D)‐printed titanium alloy prosthesis implants provide an effective solution. …”
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    Three‐dimensional (3D)‐printed titanium sternum replacement: A case report
  16. 4056
    “…Herein, we developed a fluorescence-based screening assay to search for inhibitors targeting the ZIKV NS2B-NS3 protease (ZIKVpro), and identified theaflavin-3,3’-digallate (ZP10), a natural active compound derived from black tea, as a potent ZIKV protease inhibitor in vitro (IC(50 =) 2.3 μM). …”
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    Identification of Theaflavin-3,3’-Digallate as a Novel Zika Virus Protease Inhibitor
  17. 4057
    por Crevillén, Pedro
    Publicado 2020
    “…There has been a lot of research on Polycomb functions and H3K27 methylation; however, until recently, little was known about the role of histone H3K27 demethylases. …”
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    Histone Demethylases as Counterbalance to H3K27me3 Silencing in Plants
  18. 4058
    “…A subset of glioblastomas (GBMs) harbors potentially druggable oncogenic FGFR3-TACC3 (F3T3) fusions. However, their associated molecular and clinical features are poorly understood. …”
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    Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions
  19. 4059
    “…Our studies suggest that PI(3)P generated by class III phosphoinositide 3-kinase is essential for cone photoreceptor function and survival. …”
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    Loss of Class III Phosphoinositide 3-Kinase Vps34 Results in Cone Degeneration
  20. 4060
    “…This study was aimed to investigate the inhibitory effects of Porphyra dentata (P. dentata) extract on the adipogenesis of 3T3-L1 cells and evaluate its anti-obesity effect. …”
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    Inhibitory effects of Porphyra dentata extract on 3T3-L1 adipocyte differentiation
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