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  1. 4241
    “…METHODS: Immunoblotting, real-time polymerase chain reaction, in vivo/in vitro deubiquitination, protein immunoprecipitation, immunofluorescence, and co-localization biological techniques were employed to examine the effect of ubiquitin-specific protease 3 (USP3) on APOBEC3G (A3G) stability and human immunodeficiency virus (HIV) replication. …”
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    Deubiquitinase ubiquitin-specific protease 3 (USP3) inhibits HIV-1 replication via promoting APOBEC3G (A3G) expression in both enzyme activity-dependent and -independent manners
  2. 4242
    “…The mol­ecular conformation of the title compound, C(41)H(29)ClN(4)O(3)S, is stabilized by intra­molecular C—H⋯O and C—H⋯Cl hydrogen bonds. …”
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    (1S,3′S,3a′R,6′S)-6′-(2-Chloro­phen­yl)-3′-[(2R,3S)-1-(4-meth­oxy­phen­yl)-4-oxo-3-phenyl­azetidin-2-yl]-2-oxo-3′,3′a,4′,6′-tetra­hydro-2H,2′H-spiro­[ace­naphthyl­ene-1,1′-pyrrolo­[1,2-c][1,3]thia­zole]-2′,2′-dicarbo­nitrile
  3. 4243
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    Crystal structures of ethyl (2S*,2′R*)-1′-methyl-2′′,3-dioxo-2,3-di­hydro­dispiro­[1-benzo­thio­phene-2,3′-pyrrolidine-2′,3′′-indoline]-4′-carboxyl­ate and ethyl (2S*,2′R*)-5′′-chloro-1′-methyl-2′′,3-dioxo-2,3-di­hydro­dispiro­[1-benzo­thio­phene-2,3′-pyrrolidine-2′,3′′-indoline]-4′-carboxyl­ate
  4. 4244
    por Zhou, Xin-Hui
    Publicado 2010
    “…The Mn(II) ion is coordinated by two O atoms and four water O atoms in a distorted octa­hedral geometry. Two pyrazolyl-3,5-dicarboxyl­ate anions chelate to two copper ions, forming a dinuclear unit, which further connects the Mn(II )ions into chains extending along [100]. …”
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    catena-Poly[hexaaqua-1κO,2κO,3κ(4) O-(μ(4)-3,5-dicarboxylatopyrazol-1-ido-3′:1:2:3κ(6) O (5):N (1),O (5′):N (2),O (3):O (3′))(μ(2)-3,5-dicarboxylatopyrazol-1-ido-1:2κ(4) N (2),O (3):N (1),O (5))-1,2-dicopper(II)-3-manganese(II)]
  5. 4245
    por Gao, Jing, Zhu, Bao-Yong, Cui, De-Liang
    Publicado 2008
    “…In the centrosymmetric dinuclear complex, [Cu(2)(C(8)H(4)O(5))(2)(C(10)H(8)N(2))(2)(H(2)O)(2)], the Cu(II) ion is coordinated by two N atoms from a bipyridine ligand, three O atoms from two 3-carb­oxy-2-oxidobenzoate dianions and the O atom of the water mol­ecule in a distorted octa­hedral geometry. …”
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    Bis(μ-3-carb­oxy-2-oxidobenzoato)-κ(3)O(1),O (2):O (3);κ(3) O (3):O(1),O (2)-bis­[aqua­(2,2′-bipyridine-κ(2) N,N′)copper(II)]
  6. 4246
    “…In the title compound, C(16)H(12)N(2)O(8)·2C(3)H(7)NO, the complete tricyclic compound is generated by a crystallographic centre of symmetry. …”
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    3,3′-(1,3,5,7-Tetra­oxo-2,3,6,7-tetra­hydro-1H,5H-pyrrolo[3,4-f]isoindole-2,6-di­yl)dipropanoic acid N,N-dimethyl­formamide disolvate
  7. 4247
    “…The title compound, C(18)H(23)NO(3), the adamantane derivative of norcantharidin, which is itself derived from cantharidin, crystallized with three independent mol­ecules in the asymmetric unit. …”
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    (3aRS,4SR,7RS,7aSR)-2-(Tricyclo­[3.3.1.1(3,7)]decan-1-yl)-4,5,6,7-tetra­hydro-4,7-epoxy­isoindoline-1,3-dione
  8. 4248
    “…The three stibine-substituted benzene rings make dihedral angles of 38.7 (3), 71.5 (3) and 70.0 (3)° with each other in mol­ecule A whereas these angles are 83.9 (3), 88.2 (3) and 56.8 (3)° in mol­ecule B. …”
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    [μ-Bis(diphenyl­phosphan­yl)ethane-1:2κ(2) P:P′]nona­carbonyl-1κ(3) C,2κ(3) C,3κ(3) C-(triphenyl­stibine-3κSb)-triangulo-triruthenium(0)
  9. 4249
    “…In the crystal, mol­ecules are linked through inter­molecular O—H⋯O and C—H⋯O hydrogen bonds, forming a three-dimensional network.…”
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    4-Hy­droxy-3-[(4-hy­droxy-6-methyl-2-oxo-3,6-dihydro-2H-pyran-3-yl)(3-thien­yl)meth­yl]-6-methyl-3,6-dihydro-2H-pyran-2-one
  10. 4250
    “…The asymmetric unit of the title triangulo-triruthenium compound, Ru(3)(CO)(9)(μ-Ph(2)AsCH(2)AsPh(2))(P[OCH(CH(3))(2)](3)) or [Ru(3)(C(25)H(22)As(2))(C(9)H(21)O(3)P)(CO)(9)], contains two mol­ecules of the triangulo-triruthenium complex. …”
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    [μ-Bis(diphenyl­arsanyl)methane-1:2κ(2) As:As′]nona­carbonyl-1κ(3)C,2κ(3)C,3κ(3)C-(triisoprop­yl phos­phite-3κP)-triangulo-triruthenium(0)
  11. 4251
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    4,4′-Dibromo-2,2′-{[(3aS,7aS)-2,3,3a,4,5,6,7,7a-octa­hydro-1H-1,3-benzimidazole-1,3-di­yl]bis­(methyl­idene)}diphenol
  12. 4252
    “…In the title compound C(38)H(32)N(4)O(3), one pyrrolidine ring adopts an envelope conformation with the N atom as the flap while other pyrrolidine ring adopts an twisted conformation. …”
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    1′-(1,3-Diphenyl-1H-pyrazol-4-yl)-1′′-methyl-2′,3′,5′,6′,7′,7a’-octa­hydro-1′H-dispiro­[1-benzopyran-3,2′-pyrrolizine-3′,3′′-indoline]-2′′,4-dione
  13. 4253
    “…The asymmetric unit of the title compound, [Ru(3)(C(19)H(17)P)(C(25)H(22)P(2))(CO)(9)], consists of two independent mol­ecules. …”
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    (Benzyl­diphenyl­phosphane-1κP)[μ-bis(diphenylphosphan­yl)methane-2:3κ(2) P:P′]nona­carbonyl-1κ(3) C,2κ(3) C,3κ(3) C-triangulo-triruthenium(0)
  14. 4254
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    Correction to: Synthesis, characterization and in vitro antimicrobial activity of novel fused pyrazolo[3,4-c]pyridazine, pyrazolo[3,4-d]pyrimidine, thieno[3,2-c] pyrazole and pyrazolo[3′,4′:4,5]thieno[2,3-d]pyrimidine derivatives
  15. 4255
    por Gao, Zhongjun, Li, Fahui
    Publicado 2009
    “…The three-coordinate μ(3)-oxido bridging O atom in the Sn(2)O(2) ring is attached to three Sn atoms. …”
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    Tetra­kis(μ(2)-5-methyl­pyrazine-2-carboxyl­ato)-1:2κ(3) N (1),O:O;2:3κ(3) O:N (1),O;1:2κ(2) O:O′;3:4κ(2) O:O′-octa­octyl-1κ(2) C,2κ(2) C,3κ(2) C,4κ(2) C-di-μ(3)-oxido-1:2:3κ(3) O;1:3:4κ(3) O-tetra­tin(IV)
  16. 4256
    “…BACKGROUND: Bivalent genes, of which promoters are marked by both H3K4me3 (trimethylation of histone H3 on lysine 4) and H3K27me3 (trimethylation of histone H3 on lysine 27), play critical roles in development and tumorigenesis. …”
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    H3K27me3-H3K4me1 transition at bivalent promoters instructs lineage specification in development
  17. 4257
    “…Thus there is a need to investigate new chemotherapy-targeted agents. VEGFR3 inhibitors are anti-tumour-growth and could be used to develop novel retinoblastoma-targeted agents. …”
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    2D, 3D-QSAR study and docking of vascular endothelial growth factor receptor 3 (VEGFR3) inhibitors for potential treatment of retinoblastoma
  18. 4258
    “…Activated phosphoinositide 3-kinase delta (PI3Kδ) syndrome (APDS) is an inborn error of immunity with clinical manifestations including infections, lymphoproliferation, autoimmunity, enteropathy, bronchiectasis, increased risk of lymphoma, and early mortality. …”
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    A randomized, placebo-controlled phase 3 trial of the PI3Kδ inhibitor leniolisib for activated PI3Kδ syndrome
  19. 4259
    “…Here we report a multiple-round SAR study to provide a novel bicyclic[3.3.0]proline peptidyl α-ketoamide compound 4a, which is endowed with excellent antiviral activities and pharmacokinetic properties. …”
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    Discovery of novel bicyclic[3.3.0]proline peptidyl α-ketoamides as potent 3CL-protease inhibitors for SARS-CoV-2
  20. 4260
    “…Cerium-doped gadolinium aluminum gallium garnet (Ce(3+):Gd(3)Al(3)Ga(2)O(12), Ce(3+):GAGG) ceramic is a promising scintillation material. …”
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    Structural and Scintillation Properties of Ce(3+):Gd(3)Al(3)Ga(2)O(12) Translucent Ceramics Prepared by One-Step Sintering
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