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4401por Hussain, Sajjad, Chen, Xuenian, Harrison, William T. A., Elsegood, Mark R. J., Ahmad, Saeed, Li, Shujun, Muhammad, Shabbir, Awoyelu, David“…In 2, the Tb(III) ions are coordinated by six O atoms from three bidentate chelating carboxylates, one O atom from a bridging carboxylate and two O atoms from water molecules to generate distorted tri-capped trigonal prismatic TbO(9) polyhedron. …”
Publicado 2019
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4402“…The present study has identified and validated DNA methyltransferase 3β (DNMT3B) and TET methylcytosine dioxygenase 3 (TET3) as novel ceRNAs of PTEN, with which they share multiple miRNAs, in HCT116 colorectal cancer cells. miR-4465 was identified and characterized as a miRNA that directly targets and regulates all 3 transcripts via their 3′untranslated regions (3′UTRs) through a combination of luciferase reporter assays, abrogation of miRNA response elements (MREs) via site-directed mutagenesis, target protection of MREs with locked nucleic acids, RT-qPCR assays and western blot analysis. …”
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4403por Blandin, Anne-Florence, Durand, Aurélie, Litzler, Marie, Tripp, Aurélien, Guérin, Éric, Ruhland, Elisa, Obrecht, Adeline, Keime, Céline, Fuchs, Quentin, Reita, Damien, Lhermitte, Benoit, Coca, Andres, Jones, Chris, Lelong Rebel, Isabelle, Villa, Pascal, Namer, Izzie Jacques, Dontenwill, Monique, Guenot, Dominique, Entz-Werle, Natacha“…Methods: From our biobank of pediatric brain tumor-derived models, we selected 11 pHGGs driven by the histone H3.3K28M mutation. We compared the features of four patient tumors to their paired cell lines and mouse xenografts using NGS (next generation sequencing), aCGH (array comparative genomic hybridization), RNA sequencing, WES (whole exome sequencing), immunocytochemistry, and HRMAS (high resolution magic angle spinning) spectroscopy. …”
Publicado 2019
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4404por Meyer, Britta, Immer, Carina, Kaiser, Steffen, Sharma, Sunny, Yang, Jun, Watzinger, Peter, Weiß, Lena, Kotter, Annika, Helm, Mark, Seitz, Hans-Michael, Kötter, Peter, Kellner, Stefanie, Entian, Karl-Dieter, Wöhnert, Jens“…Here we identify the so far functionally uncharacterized YfiP protein as the SAM-dependent 3-amino-3-carboxypropyl transferase catalyzing this modification and thereby extend the list of known tRNA modification enzymes in E. coli. …”
Publicado 2020
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4405por Iglesias, Isabel, Huidobro, José A., Alfonso, Belén F., Trobajo, Camino, Espina, Aránzazu, Mendoza, Rafael, García, José R.Enlace del recurso
Publicado 2020
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4406por Zhang, Yi, Wu, Miaomiao, Ma, Jiwei, Wei, Guangfeng, Ling, Yun, Zhang, Renyuan, Huang, Yunhui“…As a representative cathode, Na(2/3)Ni(1/3)Mn(2/3)O(2), the capacity contribution at a 4.2 V plateau has long been assigned to the redox of the Ni(3+)/Ni(4+) couple, while at the same time it suffers large irreversible capacity loss during the initial discharging process. …”
Publicado 2020
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4407por Dunican, Donnchadh S., Mjoseng, Heidi K., Duthie, Leanne, Flyamer, Ilya M., Bickmore, Wendy A., Meehan, Richard R.“…BACKGROUND: Thousands of mammalian promoters are defined by co-enrichment of the histone tail modifications H3K27me3 (repressive) and H3K4me3 (activating) and are thus termed bivalent. …”
Publicado 2020
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4408por Kiritsis, Christos, Manta, Stella, Parmenopoulou, Vanessa, Balzarini, Jan, Komiotis, Dimitri“…This report describes the total and facile synthesis of 3′-C-cyano & 3′-C-cyano-3′-deoxy pyrimidine pyranonucleosides. …”
Publicado 2011
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4409por Olson, Robert, Mathews, Lindsay, Liu, Mitchell, Schellenberg, Devin, Mou, Benjamin, Berrang, Tanya, Harrow, Stephen, Correa, Rohann J. M., Bhat, Vasudeva, Pai, Howard, Mohamed, Islam, Miller, Stacy, Schneiders, Famke, Laba, Joanna, Wilke, Derek, Senthi, Sashendra, Louie, Alexander V., Swaminath, Anand, Chalmers, Anthony, Gaede, Stewart, Warner, Andrew, de Gruijl, Tanja D., Allan, Alison, Palma, David A.“…BACKGROUND: A recent randomized phase II trial evaluated stereotactic ablative radiotherapy (SABR) in a group of patients with a small burden of oligometastatic disease (mostly with 1–3 metastatic lesions), and found that SABR was associated with a significant improvement in progression-free survival and a trend to an overall survival benefit, supporting progression to phase III randomized trials. …”
Publicado 2020
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4410por Saiz-Rodríguez, Miriam, Almenara, Susana, Navares-Gómez, Marcos, Ochoa, Dolores, Román, Manuel, Zubiaur, Pablo, Koller, Dora, Santos, María, Mejía, Gina, Borobia, Alberto M., Rodríguez-Antona, Cristina, Abad-Santos, Francisco“…Several cytochrome P450 (CYP) CYP3A polymorphisms were associated with reduced enzyme function. …”
Publicado 2020
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4411“…[Image: see text] (La(1–x)Dy(x))(2/3)Ca(1/3)MnO(3) samples with the perovskite structure were prepared by the sol–gel method, and the R–T curves of the samples in 0–3000 Gs magnetic field during warming and cooling processes were compared. …”
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4412“…The opportunistic pathogen Pseudomonas aeruginosa encodes three T6SSs, namely H1-, H2-, and H3-T6SS. Each T6SS possesses its own effectors and their roles are not yet fully understood. …”
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4413por López, Carlos A., Abia, Carmen, Rodrigues, Joao E., Serrano-Sánchez, Federico, Nemes, Norbert M., Martínez, José L., Fernandez-Díaz, María T., Biškup, Neven, Alvarez-Galván, Consuelo, Carrascoso, Felix, Castellanos-Gomez, Andres, Alonso, José A.“…Among the hybrid organic–inorganic perovskites MAPbX(3) (MA: methyl-ammonium CH(3)–NH(3)(+), X = halogen), the triiodide specimen (MAPbI(3)) is still the material of choice for solar energy applications. …”
Publicado 2020
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4414por Xiao, Jun, Wang, Cong, Min, Xin, Wu, Xiaowen, Liu, Yangai, Huang, Zhaohui, Fang, Minghao“…Advances in solid-state white-light-emitting diodes (WLEDs) necessitate the urgent development of highly efficient single-phase phosphors with tunable photoluminescence properties. Herein, the Tm(3+), Dy(3+), and Sm(3+) ions are incorporated into the orthorhombic NaGdTiO(4) (NGT) phosphors, resulting in phosphors that fulfill the aforementioned requirement. …”
Publicado 2020
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4415por Syafutra, Heriyanto, Yun, Jung-Ho, Yoshie, Yuya, Lyu, Miaoqiang, Takeda, Sakura Nishino, Nakamura, Masakazu, Wang, Lianzhou, Jung, Min-Cherl“…The surface status of CH(3)NH(3)PbBr(3) (MAPbBr(3)) single crystal was studied after a grazing e-beam irradiation in an ultra-high vacuum. …”
Publicado 2020
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4416“…The first mammalian extraocular opsin to be discovered, opsin 3 (OPN3), was found in the brain more than two decades ago, yet its function remains unknown. …”
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4417“…OBJECTIVE: The application of multi‐planar reconstruction of three dimensional (3D) curved surface in microsurgery of 3D printing mold assisted eyebrow arch keyhole approach was studied. …”
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4418“…[Image: see text] An experimental and theoretical study is reported to investigate the influence of bromine doping on CH(3)NH(3)Pb(I(1–x)Br(x))(3) perovskite for Br compositions ranging from x = 0 to x = 0.1, in which the material remains in the tetragonal phase. …”
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4419por Lilja, Stephanie, Oldenburg, Julia, Pointner, Angelika, Dewald, Laura, Lerch, Mariam, Hippe, Berit, Switzeny, Olivier, Haslberger, Alexander“…AIM: We investigated different bioactive compounds including epigallocatechin gallate (EGCG), anthocyanidin, resveratrol, phloretin, spermidine, butyrate, and β-hydroxybutyrate with regard to their effect on SIRT3 via NRF2 and modulation of the proinflammatory senescence-associated secretory phenotype (SASP) in senescence induced 3T3-L1 preadipocytes. …”
Publicado 2020
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4420“…Luciferase assay further verified the binding of miR‐24‐3p to the 3′‐UTR of phosphatidylinositol 3‐kinase regulatory subunit gamma (PIK3R3) mRNA and the PIK3R3 expression enhanced human umbilical vein endothelial cells functionality in vitro. …”
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