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6201Publicado 1975“…Inhibition of free movement of C3 receptors by either applying low temperature (3 degrees C) or fixing the cell surfce of lymphocytes with glutaraldehyde (2 times 10(-5) to 2 times 10(-1)%) results in loss of firm attachment of EAC142 3b cells to the lympocytes as demonstrated here by loss of rosette formation of Raji lymphoid cells. …”
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6202por Inabe, Kazunori, Ishiai, Masamichi, Scharenberg, Andrew M., Freshney, Norman, Downward, Julian, Kurosaki, Tomohiro“…To elucidate the mechanism(s) by which Vav3, a new member of the Vav family proteins, participates in B cell antigen receptor (BCR) signaling, we have generated a B cell line deficient in Vav3. …”
Publicado 2002
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6203“…The method is used to identify the genotypic patterns of three mutants of Hemophilus influenzae which are resistant to different levels of streptomycin. …”
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6204“…Complement component 3 (C3), a critical regulator of innate immunity, may also play a role in the regulation of cognate immunity, such as contact sensitivity responses. …”
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6205“…BACKGROUND: 14-3-3σ is a p53-mediated cell-cycle inhibitor in epithelial cells. …”
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6206Publicado 1992“…To investigate the functions of this enzyme in physiological systems, we have established lines of Balb-C 3T3 fibroblasts stably transfected with a constitutive tissue transglutaminase expression plasmid. …”
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6207Publicado 1991“…Mediated transport across the nuclear envelope was investigated in proliferating and growth-arrested (confluent or serum starved) BALB/c 3T3 cells by analyzing the nuclear uptake of nucleoplasmin-coated colloidal gold after injection into the cytoplasm. …”
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6208por Oldfield, Christopher J, Meng, Jingwei, Yang, Jack Y, Yang, Mary Qu, Uversky, Vladimir N, Dunker, A Keith“…RESULTS: Here we present a detailed examination of two divergent examples: 1) p53, which uses different disordered regions to bind to different partners and which also has several individual disordered regions that each bind to multiple partners, and 2) 14-3-3, which is a structured protein that associates with many different intrinsically disordered partners. …”
Publicado 2008
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6209por Liedtke, Cornelia, Cardone, Luca, Tordai, Attila, Yan, Kai, Gomez, Henry L, Figureoa, Luis J Barajas, Hubbard, Rebekah E, Valero, Vicente, Souchon, Eduardo A, Symmans, W Fraser, Hortobagyi, Gabriel N, Bardelli, Alberto, Pusztai, Lajos“…METHODS: Tumor DNA from 140 patients with stage II–III breast cancer undergoing neoadjuvant chemotherapy was sequenced for PIK3CA mutations on exons 1, 9, and 20. …”
Publicado 2008
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6210“…Here, we identified 14-3-3ε and 14-3-3ζ as Cby-binding partners using affinity purification/mass spectrometry. 14-3-3 proteins specifically recognize serine 20 within the 14-3-3–binding motif of Cby when phosphorylated by Akt kinase. …”
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6211por Burgold, Thomas, Spreafico, Fabio, De Santa, Francesca, Totaro, Maria Grazia, Prosperini, Elena, Natoli, Gioacchino, Testa, Giuseppe“…In particular, the observation that lineage-specific genes repressed in ES cells by Polycomb-mediated H3-K27 trimethylation (H3-K27me3) are demethylated and derepressed in differentiated cells posited the existence of a specific H3-K27 demethylase. …”
Publicado 2008
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6212por Rajagopalan, Sridharan, Jaulent, Agnes M., Wells, Mark, Veprintsev, Dmitry B., Fersht, Alan R.“…We have screened various p53 C-terminal phosphorylated peptides for binding to two different isoforms of 14-3-3, ɛ and γ. We found that phosphorylation at either S366 or T387 caused even tighter binding to 14-3-3. …”
Publicado 2008
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6213por Geng, Xin, Shi, Yong, Nakagawa, Akihisa, Yoshina, Sawako, Mitani, Shohei, Shi, Yigong, Xue, Ding“…In Caenorhabditis elegans, however, no IAP homolog or caspase inhibitor has been identified, calling into question how the cell-killing caspase CED-3 can be negatively regulated. Here we show that inactivation of the C. elegans csp-3 gene, which encodes a protein similar to the small subunit of the CED-3 caspase, causes cells that normally live to undergo apoptosis in a CED-3–dependent manner. …”
Publicado 2008
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6214por Wang, Zhihui, Tropè, Claes G, Suo, Zhenhe, Trøen, Gunhild, Yang, Guanrui, Nesland, Jahn M, Holm, Ruth“…BACKGROUND: 14-3-3 sigma (σ) promotes G2/M cell cycle arrest by sequestering cyclin B1-CDC2 complex in cytoplasm. …”
Publicado 2008
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6215“…The spontaneous transfer of drug resistance genes has been shown to take place between cultured mammalian NIH-3T3 cells and occurs with a hierarchy of transfer efficiencies, transformed cells being more efficient than non-transformed cells. …”
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6216por Kolasinska-Zwierz, Paulina, Down, Thomas, Latorre, Isabel, Liu, Tao, Liu, X. Shirley, Ahringer, Julie“…We find that C. elegans genes show similarities in distributions of histone modifications to those of other organisms, with H3K4me3 near transcription start sites, H3K36me3 in the body of genes, and H3K9me3 enriched on silent genes. …”
Publicado 2009
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6217“…The database of 3D interacting domains (3did) is a collection of protein interactions for which high-resolution 3D structures are known. 3did exploits structural information to provide the crucial molecular details necessary for understanding how protein interactions occur. …”
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6218por Katargin, Alexey N, Pavlova, Larissa S, Kisseljov, Fjodor L, Kisseljova, Natalia P“…We previously identified non-satellite 3.3-kb repeats associated with facioscapulohumeral muscular dystrophy (FSHD) as hypermethylated in cervical cancer in genome-wide screening. …”
Publicado 2009
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6219por Hamdy, Emad, El-Raouf, Ahmed Abd, El-Hemaly, Mohamed, Salah, Tarek, El-Hanafy, Ehab, Mostafa, Mohamed, Hak, Nabil GadEl“…All patients completed the Gastroesophageal Reflux Disease-Health Related Quality Of Life (GERD-HRQL) questionnaire both pre- and postoperatively (early within 3 months after operation and late after 3 years). …”
Publicado 2008
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6220por Ueshima, Kazuhito, Minakata, Yoshiaki, Sugiura, Hisatoshi, Yanagisawa, Satoru, Ichikawa, Tomohiro, Akamatsu, Keiichirou, Hirano, Tsunahiko, Nakanishi, Masanori, Matsunaga, Kazuto, Yamagata, Toshiyuki, Ichinose, Masakazu“…BACKGROUND: We have recently developed a new technique for quantitatively measuring protein-bound 3-nitrotyrosine (3-NT), a footprint of nitrosative stress, utilizing high-performance liquid chromatography with an electrochemical detection (HPLC-ECD) system. …”
Publicado 2007
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