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  1. 6221
    por Simonsen, Anne, Tooze, Sharon A.
    Publicado 2009
    “…Here we discuss the cross talk between autophagy and intracellular compartments, highlighting recent exciting data about the role and regulation of the Vps34 class III phosphatidylinositol (PI) 3-kinase in autophagy.…”
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    Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
  2. 6222
    “…In order to identify genes critical for adipogeneis, we took a novel approach based on phenotype change of individual cell, to search for genes with regulatory roles in adipogenesis genome-wide in 3T3-L1 cells. METHODS: Lentivirus-based inducible random homologous knockdown was used for the screening of functional gene that altered lipid formation in the adipocyte during differentiation. …”
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    Involvement of an alternatively spliced mitochondrial oxodicarboxylate carrier in adipogenesis in 3T3-L1 cells
  3. 6223
    “…Here, we have determined the crystal structure of the A(3)B(3) subcomplex of V-ATPase at 2.8 Å resolution. …”
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    Crystal structure of A(3)B(3) complex of V-ATPase from Thermus thermophilus
  4. 6224
    “…Protein cleavage is a common feature in human neurodegenerative disease. Ataxin-3 protein with an expanded polyglutamine (polyQ) repeat causes spinocerebellar ataxia type-3 (SCA3), also called Machado–Joseph disease, and is cleaved in mammalian cells, transgenic mice and SCA3 patient brain tissue. …”
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    Preventing Ataxin-3 protein cleavage mitigates degeneration in a Drosophila model of SCA3
  5. 6225
    “…ULM comprises S776 of Atx1 and overlaps with a nuclear localization signal and a 14-3-3 binding motif. We demonstrate that phosphorylation of S776 provides the molecular switch which discriminates between 14-3-3 and components of the spliceosome. …”
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    Phosphorylation of S776 and 14-3-3 Binding Modulate Ataxin-1 Interaction with Splicing Factors
  6. 6226
    “…A random-effects meta-analysis of all three samples was significant (p = 3 × 10(−6); OR=1.32), with no heterogeneity. …”
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    Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder
  7. 6227
    “…ASP expression was increased during 3T3-L1 differentiation and reached a peak at day 8 with cell maturation. …”
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    Role of protease inhibitors and acylation stimulating protein in the adipogenesis in 3T3-L1 cells
  8. 6228
    “…Mixed Lineage Kinase 3 (MLK3) is a mitogen-activated protein kinase kinase kinase (MAPKKK) that is activated by Tumor Necrosis Factor-α (TNF-α) and specifically activates c-Jun N-terminal kinase (JNK) upon TNF-α stimulation. …”
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    TRAF2-MLK3 interaction is essential for TNF-α-induced MLK3 activation
  9. 6229
    “…In this paper, a panel of 24 breast cell lines was grown in 3D culture, their morphology was imaged through phase contrast microscopy, and computational methods were developed to segment and represent each colony at multiple dimensions. …”
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    Molecular Predictors of 3D Morphogenesis by Breast Cancer Cell Lines in 3D Culture
  10. 6230
    “…These results suggest that 14-3-3β is a downstream effector of xCT in KS to mediate the cell proliferation.…”
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    Overexpression of xCT induces up-regulation of 14-3-3β in Kaposi's sarcoma
  11. 6231
    “…The total synthesis of (3R,5R)-harzialactone A (1) and its (3R,5S)-isomer (2) is described. …”
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    Synthesis of (3R,5R)-harzialactone A and its (3R,5S)-isomer
  12. 6232
    “…Three GSKs have already been shown to relay BR responses, including phosphorylation of the transcriptional regulator BES1. …”
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    ASKθ, a group-III Arabidopsis GSK3, functions in the brassinosteroid signalling pathway
  13. 6233
    “…To identify regulatory molecules which play key roles in the development of obesity, we investigated the transcriptional profiles in 3T3-L1 cells at early stage of differentiation and analyzed the promoter sequences of differentially regulated genes. …”
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    Transcriptome analysis and promoter sequence studies on early adipogenesis in 3T3-L1 cells
  14. 6234
    “…When ferrous ammonium sulfate and cobalt chloride were added to sodium tungstate, hexagonal WO(3)nanowire clusters and hexagonal WO(3)nanorods were obtained, respectively. …”
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    Controlled Growth of WO(3)Nanostructures with Three Different Morphologies and Their Structural, Optical, and Photodecomposition Studies
  15. 6235
    “…The aims of this study were to establish the impact of eicosapentaenoic acid (EPA; C20:5n-3) in comparison to SFA (STA; stearic acid, C18:0) and MUFA (OLA; oleic acid, C18:1n-9) on 3T3-L1 adipocyte LD formation, regulation of genes central to LD function and adipokine responsiveness. …”
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    Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes
  16. 6236
    “…In addition, the protein level of 14-3-3epsilon in stage III or IV tumours was significantly lower than that in stage I or II tumours. …”
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    14-3-3epsilon contributes to tumour suppression in laryngeal carcinoma by affecting apoptosis and invasion
  17. 6237
    “…RESULTS: We have optimized a process for bio-catalytic production of 3-substituted catechols viz. 3-nitrocatechol (3-NC) and 3-methylcatechol (3-MC) at pilot scale. …”
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    A process optimization for bio-catalytic production of substituted catechols (3-nitrocatechol and 3-methylcatechol
  18. 6238
    “…In the mol­ecule of the title compound, C(17)H(15)BrO(3), the rings make a dihedral angle of 75.54 (17)°. …”
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    (E)-Methyl 3-{3-[(4-bromo­phen­oxy)­methyl]phen­yl}acrylate
  19. 6239
    por Ma, Chun-Yan, Song, Wen-Dong, Xi, Dan-Li
    Publicado 2007
    “…In the title complex, [Cd(C(5)H(4)NO)(C(12)H(9)O(2))(H(2)O)](n), each Cd(II) atom is coordinated by two carboxylate O atoms from one 1-naphthyl­acetate ligand, two hydroxyl O atoms from two pyridin-3-olate ligands, one N atom from another pyridin-3-olate ligand and one water mol­ecule, and displays a distorted octa­hedral coordination geometry. …”
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    Poly[[aqua­(1-naphthyl­acetato)cadmium(II)]-μ(3)-pyridin-3-olato]
  20. 6240
    “…Whilst the larger RPA subunits, Rpa1 and Rpa2, have essential interactions with ssDNA, the molecular functions of the smallest subunit Rpa3 are unknown. Here, we investigate the Rpa3 ortholog Ssb3 in Schizosaccharomyces pombe and find that it is dispensable for cell viability, checkpoint signaling, RPA foci formation, and meiosis. …”
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    Critical Functions of Rpa3/Ssb3 in S-Phase DNA Damage Responses in Fission Yeast
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