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  1. 6501
    “…[Image: see text] The 3,3′-di-O-methyl derivative (15) of the bis-C-aryl glycoside natural product ardimerin (1) has been synthesized in 11 steps from 2,3,4,6-tetrabenzylglucose (2) and 1,2,3-trimethoxybenzene (3). …”
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    Synthesis of 3,3′-Di-O-methyl Ardimerin and Exploration of Its DNA Binding Properties
  2. 6502
    “…In this review, we summarize advances in the involvement of the PI3K/AKT/GSK-3β pathways in cell signaling of neuronal cells. …”
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    Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer’s disease
  3. 6503
    “…Objective: This study was designed to evaluate the expression of the key regulator of this signaling pathway GSK3-β and its presumed role in azoospermia. Materials and Methods: WNT3a protein concentration and GSK3-β gene expression levels were measured and compared between two groups of infertile men. …”
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    Expression of Glycogen synthase kinase 3-β (GSK3-β) gene in azoospermic men
  4. 6504
    “…We demonstrate the use of animated 3D models embedded in PDF documents, which combine the advantages of both movie and interactivity, based on the example of preserved Trigonopterus weevils. …”
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    Three-Dimensional Reconstructions Come to Life – Interactive 3D PDF Animations in Functional Morphology
  5. 6505
    “…1α,25-Dihydroxyvitamin D3 [1,25(OH)(2)D(3)] has been demonstrated to inhibit the growth of cancer cells. …”
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    Synergy of 1,25-dihydroxyvitamin D3 and carboplatin in growth suppression of SKOV-3 cells
  6. 6506
    “…Vascular endothelial growth factor receptor 3 (VEGFR-3) supports tumor lymphangiogenesis. It was originally identified as a lymphangiogenic factor expressed in lymphatic endothelial cells. …”
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    Novel peptides suppress VEGFR-3 activity and antagonize VEGFR-3-mediated oncogenic effects
  7. 6507
    “…The purpose of this study was to determine the effects of erythromycin (EM) on polymethylmethacrylate (PMMA) particle-challenged MC3T3 osteoblast precursor cells. Methods. MC3T3 cells were pretreated with EM (0–10 μg/mL) and then stimulated with PMMA (1 mg/mL). …”
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    Mitigative Effect of Erythromycin on PMMA Challenged Preosteoblastic MC3T3-E1 Cells
  8. 6508
    “…The largely cytoplasmic KMT SMYD3 (SET and MYND domain containing protein 3) is overexpressed in numerous human tumors(2-4). …”
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    SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
  9. 6509
    “…Since the initial cloning of fractalkine/CX3CL1, it was proposed that the only known member of the CX3C or δ subfamily of chemotactic cytokines could play some significant role in the nervous system, due to its high expression on neurons. …”
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    Modulating neurotoxicity through CX3CL1/CX3CR1 signaling
  10. 6510
    “…Mutations in known tumor suppressors DNMT3A (p.G728D) and ASXL1 (p.E657fs), consistent with mutations of known consequence in acute myeloid leukemia, were identified. …”
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    ASXL1 and DNMT3A mutation in a cytogenetically normal B3 thymoma
  11. 6511
    “…In animals, replication-independent incorporation of nucleosomes containing the histone variant H3.3 enables global reprogramming of histone modifications and transcriptional profiles. …”
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    The HIRA complex that deposits the histone H3.3 is conserved in Arabidopsis and facilitates transcriptional dynamics
  12. 6512
    “…Unlike histone H3, which is present only in S phase, the variant histone H3.3 is expressed throughout the cell cycle [1] and is incorporated into chromatin independent of replication [2]. …”
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    Histone H3.3 Is Required to Maintain Replication Fork Progression after UV Damage
  13. 6513
    por Shek, Daniel Tan Lei, Yu, Lu
    Publicado 2014
    “…The present study attempted to examine the construct validity of the Chinese version of Psycho-Educational Profile-3rd edition (CPEP-3). The CPEP-3 was administered to a sample of 455 children with ASD and a comparison group of 281 children without ASD. …”
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    Construct Validity of the Chinese Version of the Psycho-Educational Profile-3rd Edition (CPEP-3)
  14. 6514
    “…CONCLUSION: The epilogue was that the additional finding changed the final Gleason score to 3 + 3 = 6 with tertiary pattern 4 and the stage to pT3a. …”
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    Does prostate acinar adenocarcinoma with Gleason Score 3 + 3 = 6 have the potential to metastasize?
  15. 6515
    “…In this study, we investigated the antiviral activities of seven ginsenosides [protopanaxatriol (PT) type: Re, Rf, and Rg2; protopanaxadiol (PD) type: Rb1, Rb2, Rc, and Rd)] against coxsackievirus B3 (CVB3), enterovirus 71 (EV71), and human rhinovirus 3 (HRV3). …”
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    Antiviral activity of ginsenosides against coxsackievirus B3, enterovirus 71, and human rhinovirus 3
  16. 6516
    “…We show the presence of high-affinity binding site for STAT3 in the 5′-flanking region of the Tpx2 gene, which is in vivo bound by activated STAT3. …”
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    Upregulation of TPX2 by STAT3: Identification of a Novel STAT3 Binding Site
  17. 6517
    “…The aim of this study was to determine whether mulberry leaf ethanol extract (MLEE) affects adipogenesis in 3T3-L1 adipocytes. MATERIALS/METHODS: The 3T3-L1 adipocytes were treated with different doses of MLEE for 8 days starting 2 days post-confluence. …”
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    Anti-adipogenic effect of mulberry leaf ethanol extract in 3T3-L1 adipocytes
  18. 6518
    “…Here, we report the photo-luminescence excitation spectroscopy results of single Pr(3+) ions in a bulk crystal of LaF(3) at 1.5 K. …”
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    Spectroscopy of single Pr(3+) ion in LaF(3) crystal at 1.5 K
  19. 6519
    “…Here we critically investigated the effects of the excitation parameters of low-intensity pulsed ultrasound (LIPUS) stimulation on proliferation of MC3T3-E1 preosteoblastic cells in monolayer cultures. …”
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    Ultrasound stimulation increases proliferation of MC3T3-E1 preosteoblast-like cells
  20. 6520
    “…Three observers evaluated right and left lateral recumbent radiographs from 56 adult English Bulldogs independently on three different occasions. …”
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    Comparison between tracheal ratio methods used by three observers at three occasions in English Bulldogs
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