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6601por Schelhaas, Sonja, Heinzmann, Kathrin, Bollineni, Vikram R., Kramer, Gerbrand M., Liu, Yan, Waterton, John C., Aboagye, Eric O., Shields, Anthony F., Soloviev, Dmitry, Jacobs, Andreas H.“…The positron emission tomography (PET) tracer 3'-deoxy-3'-[(18)F]fluorothymidine ([(18)F]FLT) has been proposed to measure cell proliferation non-invasively in vivo. …”
Publicado 2017
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6602“…Recent high-throughput chromosome conformation capture studies have outlined the principles of these elements interacting and regulating the expression of distal target genes through three-dimensional (3D) chromatin looping. Here we present 3DSNP, an integrated database for annotating human noncoding variants by exploring their roles in the distal interactions between genes and regulatory elements. 3DSNP integrates 3D chromatin interactions, local chromatin signatures in different cell types and linkage disequilibrium (LD) information from the 1000 Genomes Project. 3DSNP provides informative visualization tools to display the integrated local and 3D chromatin signatures and the genetic associations among variants. …”
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6603“…METHODS AND RESULTS: Here, we identify a novel candidate therapeutic target, trefoil factor 3 (TFF3) which overexpressed in cervical cancer cells and was associated with reduced postoperative survival. …”
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6604por Wang, Wenbiao, Xiao, Feng, Wan, Pin, Pan, Pan, Zhang, Yecheng, Liu, Fang, Wu, Kailang, Liu, Yingle, Wu, Jianguo“…Activation of NLRP3 inflammasome is important for effective host defense against invading pathogen. …”
Publicado 2017
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6605por Ivanov, Alexander, Kaczkowska, Beata A., Khan, Saadat A., Ho, Jean, Tavakol, Morteza, Prasad, Ashok, Bhumireddy, Geetha, Beall, Allan F., Klem, Igor, Mehta, Parag, Briggs, William M., Sacchi, Terrence J., Heitner, John F.“…CONTEXT: Over the past three decades, industry sponsored research expanded in the United States. …”
Publicado 2017
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6607por Zhang, Shu, Mukherjee, Seema, Fan, Xuejun, Salameh, Ahmad, Mujoo, Kalpana, Huang, Zhao, Li, Leike, Salazar, Georgina To'a, Zhang, Ningyan, An, Zhiqiang“…HER3/ErbB3 has emerged as a new therapeutic target for cancer. …”
Publicado 2016
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6608“…The phase equilibrium diagram was determined for the Sc(2)O(3)-Ga(2)O(3) system. A quenching furnace, wound with 60 percent Pt—40 percent Rh wire, was employed for experiments conducted at temperatures up to 1,800 °C. …”
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6609por Lung, Tom, Howard, Kirsten, Etherton-Beer, Christopher, Sim, Moira, Lewin, Gill, Arendts, Glenn“…The multi-attribute utility instrument most commonly used and recommended to assess health-related quality of life in the nursing home population is the three-level EuroQol EQ-5D-3L. To date, there have been no studies using the Health Utilities Index Mark III (HUI3). …”
Publicado 2017
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6610por Wagh, Akshaya D., Sharma, Manoranjan, Mahapatra, Jogeshwar, Chatterjee, Abhijeet, Jain, Mukul, Addepalli, Veeranjaneyulu“…However, the kinases like Phosphoinositide 3 kinase (PI3K) and Janus kinase 3 (JAK3) are involved in mast cell proliferation, activation, recruitment, migration, and prolonged survival of inflammatory cells. …”
Publicado 2017
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6611The longstanding challenge of the nanocrystallization of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX)“…The most symptomatic example is the longstanding challenge of the nanocrystallization of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX). Recent advances in crystallization processes and milling technology mark the beginning of a new area which will hopefully lead the pyroelectric industry to finally embrace nanotechnology. …”
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6612“…The FMS-like tyrosine kinase-3 (FLT3) gene is the most commonly mutated gene in acute myeloid leukemia (AML), and patients carrying internal tandem duplication (ITD) mutations have a poor prognosis. …”
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6613“…In this study, a soft sensor-based three-dimensional (3-D) finger motion measurement system is proposed. …”
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6614“…The mechanisms of myeloma cells migration/invasion have remained unclear. Herein, we found SH3GL3 was highly expressed in the CD138-negative (CD138(−)) myeloma cells. …”
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6615por Park, Seon-Joo, Kim, Hong Beum, Kim, Jeeho, Park, Sanggon, Kim, Seok Won, Lee, Jung-Hee“…The p53-inducible gene 3 (PIG3), initially identified as a gene downstream of p53, plays an important role in the apoptotic process triggered by p53-mediated reactive oxygen species (ROS) production. …”
Publicado 2017
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6616por Baumbach, Sebastian F., Binder, Jakob, Synek, Alexander, Mück, Fabian G., Chevalier, Yan, Euler, Ekkehard, Langs, Georg, Fischer, Lukas“…METHODS: The local radiographic database was screened for CT-scans of intact radii. 1) The data sets were segmented and 3D surface models generated. Statistical 3D shape models were computed (overall, gender and side separate) and the 3D shape variation assessed by evaluating the number of modes. 2) Anatomical landmarks were assigned and used to define three standardized cross-sectional cut planes perpendicular to the main axis. …”
Publicado 2017
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6617por Bastide, Amandine, Peretti, Diego, Knight, John R.P., Grosso, Stefano, Spriggs, Ruth V., Pichon, Xavier, Sbarrato, Thomas, Roobol, Anne, Roobol, Jo, Vito, Davide, Bushell, Martin, von der Haar, Tobias, Smales, C. Mark, Mallucci, Giovanna R., Willis, Anne E.“…Cooling and hypothermia are profoundly neuroprotective, mediated, at least in part, by the cold shock protein, RBM3. However, the neuroprotective effector proteins induced by RBM3 and the mechanisms by which mRNAs encoding cold shock proteins escape cooling-induced translational repression are unknown. …”
Publicado 2017
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6618“…Zinc transporter 3 (ZnT3), a member of the SLC 30 zinc transporter family, is involved in the transport of zinc ions from the cytoplasm into synaptic vesicles or intracellular organelles. …”
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6619por Cardoso, F., Costa, A., Senkus, E., Aapro, M., André, F., Barrios, C. H., Bergh, J., Bhattacharyya, G., Biganzoli, L., Cardoso, M. J., Carey, L., Corneliussen-James, D., Curigliano, G., Dieras, V., El Saghir, N., Eniu, A., Fallowfield, L., Fenech, D., Francis, P., Gelmon, K., Gennari, A., Harbeck, N., Hudis, C., Kaufman, B., Krop, I., Mayer, M., Meijer, H., Mertz, S., Ohno, S., Pagani, O., Papadopoulos, E., Peccatori, F., Penault-Llorca, F., Piccart, M. J., Pierga, J. Y., Rugo, H., Shockney, L., Sledge, G., Swain, S., Thomssen, C., Tutt, A., Vorobiof, D., Xu, B., Norton, L., Winer, E.Enlace del recurso
Publicado 2017
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6620por Sausa, Rosario C., Pesce-Rodriguez, Rose A., Wingard, Leah A., Guzmán, Pablo E., Sabatini, Jesse J.“…Inversion-related rings are in close slip-stacked proximity, with an interplanar separation of 3.101 (3) Å [centroid–centroid distance = 3.701 (3) Å]. …”
Publicado 2017
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