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  1. 6621
    “…In this study, we focus on the role of class III phosphatidylinositol 3-kinase (PtdIns3K, corresponding to yeast Vps34) in order to identify central regulators of PND. …”
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    Role of class III phosphatidylinositol 3-kinase during programmed nuclear death of Tetrahymena thermophila
  2. 6622
    “…BCl(3)‐induced borylative cyclization of aryl‐alkynes possessing ortho‐EMe (E=S, O) groups represents a simple, metal‐free method for the formation of C3‐borylated benzothiophenes and benzofurans. …”
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    BCl(3)‐Induced Annulative Oxo‐ and Thioboration for the Formation of C3‐Borylated Benzofurans and Benzothiophenes
  3. 6623
    “…Thus, our study gives important insight for Polycomb-mediated repression in lower eukaryotes, uncovering a previously unknown link between H3K27me3 targets and protein splicing.…”
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    Characterization of the Polycomb-Group Mark H3K27me3 in Unicellular Algae
  4. 6624
    “…Here, we characterize the interactions between the CBS-pair (Bateman) domain of CNNM3 and either PRL2 or PRL3 using X-ray crystallography, isothermal titration calorimetry, and activity assays. …”
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    PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3
  5. 6625
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    Properties of PEMA-NH(4)CF(3)SO(3) Added to BMATSFI Ionic Liquid
  6. 6626
    “…In this study, we report that PHLDA3, a p53 target gene, functions as a blockage of iPSCs generation by activating the Akt-GSK3β pathway. …”
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    PHLDA3 impedes somatic cell reprogramming by activating Akt-GSK3β pathway
  7. 6627
    “…Here we demonstrate that sortilin is also involved in retrograde protein traffic. In cultured 3T3-L1 adipocytes, sortilin together with retromer rescues Glut4 from degradation in lysosomes and retrieves it to the TGN, where insulin-­responsive vesicles are formed. …”
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    Sortilin and retromer mediate retrograde transport of Glut4 in 3T3-L1 adipocytes
  8. 6628
    “…The aim of this study was to evaluate the associations between the signal transducer and activator of transcription 3 (STAT3) promoter methylation, mRNA expression and the invasiveness or recurrence of PAs and patient clinical characteristics. …”
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    Signal transducer and activator of transcription 3 (STAT3) promoter methylation and expression in pituitary adenoma
  9. 6629
    por Liu, Xing, Kong, Jian-qiang
    Publicado 2017
    “…The search of new substrates with pharmaceutical and industrial potential for biocatalysts including cytochrome P450 enzymes is always challenging. Cytochrome P450 BM3 mutant 139-3, a versatile biocatalyst, exhibited hydroxylation activities towards fatty acids and alkanes. …”
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    Steroids hydroxylation catalyzed by the monooxygenase mutant 139-3 from Bacillus megaterium BM3
  10. 6630
    “…Methods: In steroid-free conditions, 3T3-L1 pre-adipocytes were induced to differentiate in the presence of EDs, singularly or in mixtures, for 2 days. …”
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    Early endocrine disruptors exposure acts on 3T3-L1 differentiation and endocrine activity
  11. 6631
    “…We found that echinomycin, a potent HIF-1 inhibitor, completely inhibited adipogenesis in 3T3-L1 WAT preadipocytes by affecting the early phase of mitotic clonal expansion. …”
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    Echinomycin inhibits adipogenesis in 3T3-L1 cells in a HIF-independent manner
  12. 6632
    “…Tryptophan degradation through kynurenine pathway produces some metabolites with redox properties as 3-hydroxykynurenine (3-HK) and 3-hydroxyanthranilic acid (3-HANA). …”
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    3-Hydroxykynurenine and 3-Hydroxyanthranilic Acid Enhance the Toxicity Induced by Copper in Rat Astrocyte Culture
  13. 6633
    “…It was found that an optimized strain cultivated in a shaking incubator is able to produce up to 52.1% of the DCW of PHB-V (10.8 g L(−1)) with 12.3%mol of PHV fraction. Although further optimization of cultivation conditions in a fed-batch bioreactor led to lower polymer content (15.3% of the DCW of PHB-V), the PHV fraction and total polymer level increased to 23.1%mol and 11.6 g L(−1) respectively. …”
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    Enhancement of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) accumulation in Arxula adeninivorans by stabilization of production
  14. 6634
    por Xia, Wenlong, Jiao, Jianwei
    Publicado 2017
    “…Overexpression of the H3.3, MOF, and GLI1 could rescue the abnormal phenotype caused by H3.3 knockdown in the embryonic brain, but H3.1 or H3.3K36R overexpression can not rescue it. …”
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    Histone variant H3.3 orchestrates neural stem cell differentiation in the developing brain
  15. 6635
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    A multidimensional phasor approach reveals LAURDAN photophysics in NIH-3T3 cell membranes
  16. 6636
    “…Three-dimensional (3D) printing is a rapidly emerging technology that promises to transform tissue engineering into a commercially successful biomedical industry. …”
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    In situ repair of bone and cartilage defects using 3D scanning and 3D printing
  17. 6637
    “…The apolipoprotein B messenger RNA-editing, enzyme-catalytic, polypeptide-like 3 (APOBEC3) family of cytidine deaminases plays an important role in the innate immune response to viral infections by editing viral genomes. …”
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    Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression
  18. 6638
    “…The phosphoserine/phosphothreonine-binding protein 14-3-3 is known to regulate actin; this function has been previously attributed to sequestration of phosphorylated cofilin. 14-3-3 was identified as an actin-associated protein in the deep-branching eukaryote Giardia lamblia; however, Giardia lacks cofilin and all other canonical actin-binding proteins (ABPs). …”
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    14-3-3 Regulates Actin Filament Formation in the Deep-Branching Eukaryote Giardia lamblia
  19. 6639
    “…BACKGROUND: Reduced expression of tripartite motif-containing 3 (TRIM3) has been reported to be involved in the pathogenesis of human glioblastoma. …”
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    Tripartite motif-containing 3 (TRIM3) inhibits tumor growth and metastasis of liver cancer
  20. 6640
    “…We report enzymatic and asymmetric synthetic studies, which define the product of TMLH catalysis as (2S,3S)-3-hydroxy-N (ε)-trimethyllysine.…”
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    Human carnitine biosynthesis proceeds via (2S,3S)-3-hydroxy-N (ε)-trimethyllysine
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