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  1. 6681
    “…In the Xenopus neural plate, PCP is marked by the enrichment of the conserved proteins Prickle3 and Vangl2 at anterior cell boundaries. Here we show that the apical determinant Par3 is also planar polarized in the neuroepithelium, suggesting a role for Par3 in PCP. …”
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    Par3 interacts with Prickle3 to generate apical PCP complexes in the vertebrate neural plate
  2. 6682
    “…The BH3-only family member BNIP3 has been described as either promoting cell survival or cell death. …”
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    The BH3 only Bcl-2 family member BNIP3 regulates cellular proliferation
  3. 6683
    “…The centromere specific histone H3 variant CENP-A/CENH3 specifies where the kinetochore is formed in most eukaryotes. …”
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    HJURP antagonizes CENP-A mislocalization driven by the H3.3 chaperones HIRA and DAXX
  4. 6684
    “…Here, we report that FGFBP3 (BP3) modulates fat and glucose metabolism in mouse models of metabolic syndrome. …”
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    Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism
  5. 6685
    “…Through data integration of three proteomics data sets we found that BV02 modulates numerous protein-protein interactions involving 14-3-3 proteins in our PCa models. …”
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    Structure-based assessment and network analysis of targeting 14-3-3 proteins in prostate cancer
  6. 6686
    “…Recently, a study identified that cullin 3 (CUL3) was significantly mutated and deleted in ESCC. …”
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    Variants in the 3'-untranslated region of CUL3 is associated with risk of esophageal squamous cell carcinoma
  7. 6687
    por Ye, Mingfu, Shi, Bin
    Publicado 2018
    “…We detected the cytotoxicity of TiO(2) and ZrO(2) NPs in osteoblast-like 3T3-E1 cells and found that reactive oxygen species (ROS) played a crucial role in the TiO(2) and ZrO(2) NP-induced cytotoxicity with concentration-dependent manner. …”
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    Zirconia Nanoparticles-Induced Toxic Effects in Osteoblast-Like 3T3-E1 Cells
  8. 6688
    “…BACKGROUND: 3D printing is an ideal manufacturing process for creating patient-matched models (anatomical models) for surgical and interventional planning. …”
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    3D printing for congenital heart disease: a single site’s initial three-yearexperience
  9. 6689
    “…N(6)-Methyladenosine (m(6)A) modification of messenger RNA (mRNA) is emerging as an important regulator of gene expression that impacts different developmental and biological processes, and altered m(6)A homeostasis is linked to cancer(1-5). m(6)A is catalyzed by METTL3 and enriched in the 3’ untranslated region (3’ UTR) of a large subset of mRNAs at sites close to the stop codon(5). …”
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    mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis
  10. 6690
    “…Additionally, cells cultured on the 1:3 ratio matrices had more nodules than those on other matrices. …”
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    Osteogenesis-Related Behavior of MC3T3-E1 Cells on Substrates with Tunable Stiffness
  11. 6691
    “…Moreover, IL-9 stimulation inhibited suppressor of cytokine signaling 3 (SOCS3) expression and wound healing ability in colonic epithelial cells and promoted the phosphorylation level of signal transducers and activators of transcription 3 (STAT3). …”
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    IL-9 promotes the pathogenesis of ulcerative colitis through STAT3/SOCS3 signaling
  12. 6692
    “…A new 3, 3”-biflavanone, neochamaejasmin C (1), was isolated from the roots of Stellera chamaejasme L., together with four known compounds. …”
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    A New C-3/C-3”-Biflavanone from the Roots of Stellera chamaejasme L
  13. 6693
    “…The thermal and mechanical properties of poly(3-hydroxybutyrate-co-3-hydroxyvalerate, PHBV) composites filled with boron nitride (BN) particles with two different sizes and shapes were studied by scanning electron microscopy (SEM), differential scanning calorimetry (DSC), X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), thermal gravimetric analysis (TGA) and mechanical testing. …”
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    The Effect of Boron Nitride on the Thermal and Mechanical Properties of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)
  14. 6694
    “…Non-fused 3,6-dihydro-2H-1,3-thiazine-2-thiones constitute a so far rather unexplored class of compounds, with the latest report dating back more than two decades. …”
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    Multicomponent Synthesis of 3,6-Dihydro-2H-1,3-thiazine-2-thiones
  15. 6695
    por Tu, Pham Thi Be, Tawata, Shinkichi
    Publicado 2014
    “…Finally, none of the three compounds reduced 3T3-L1 adipocyte viability. …”
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    Anti-Obesity Effects of Hispidin and Alpinia zerumbet Bioactives in 3T3-L1 Adipocytes
  16. 6696
    por Jung, Hye-Won, Park, Inae, Ghil, Sungho
    Publicado 2014
    “…Using the intracellular loop 3 of CB1R as bait, we identified 14-3-3β as an interacting partner of CB1R and confirmed their interaction using affinity-binding assays. 14-3-3β has been reported to induce a cell cycle delay at the G(2)/M phase. …”
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    Cannabinoid receptor activation inhibits cell cycle progression by modulating 14-3-3β
  17. 6697
    “…We recently demonstrated that the circadian clock component CRY2 is an essential cofactor in the SCF(FBXL3)-mediated ubiquitination of c-MYC. Because our demonstration that CRY2 recruits phosphorylated substrates to SCF(FBXL3) was unexpected, we investigated the scope of this role by searching for additional substrates of FBXL3 that require CRY1 or CRY2 as cofactors. …”
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    The circadian E3 ligase complex SCF(FBXL3+CRY) targets TLK2
  18. 6698
    “…Among them, several triterpenoids enhanced insulin stimulated glucose uptake in both 3T3-L1 adipocytes and C2C12 myotubes. Furthermore, compound 1 dose-dependently increased glucose uptake through activating AMP-activated protein kinase (AMPK)-p38 pathway. …”
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    Triterpenoids from Cyclocarya paliurus that Enhance Glucose Uptake in 3T3-L1 Adipocytes
  19. 6699
    “…UBE3A is an E3 ubiquitin ligase encoded by an imprinted gene whose maternal deletion or duplication leads to distinct neurodevelopment disorders Angelman and Dup15q syndromes. …”
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    UBE3A: An E3 Ubiquitin Ligase With Genome-Wide Impact in Neurodevelopmental Disease
  20. 6700
    “…Our aim was to evaluate the triglyceride-lowering effects of Q metabolites in mature and pre-adipocytes, and to compare them to those induced by Q. 3T3-L1 mature and pre-adipocytes were treated with 0.1, 1 and 10 µM of Q, tamarixetin (TAM), isorhamnetin (ISO), quercetin-3-O-glucuronide (3G), quercetin-3-O-sulfate (3S), as well as with 3S and quercetin-4-O-sulfate (4S) mixture (3S+4S). …”
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    Effects of Quercetin Metabolites on Triglyceride Metabolism of 3T3-L1 Preadipocytes and Mature Adipocytes
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