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  1. 6941
    Publicado 2022
    “…Modeling 3D genome organisation has been booming in the last years thanks to the availability of experimental datasets of genomic contacts. …”
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    3DGenBench: a web-server to benchmark computational models for 3D Genomics
  2. 6942
    “…Pathogen recognition and TNF receptors signal via receptor interacting serine/threonine kinase-3 (RIPK3) to cause cell death, including MLKL-mediated necroptosis and caspase-8-dependent apoptosis. …”
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    Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
  3. 6943
    por Niu, Haibo, Liu, Yachao, Shi, Jing, Wang, Vei
    Publicado 2022
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    Large Vertical Piezoelectricity in a Janus Cr(2)I(3)F(3) Monolayer
  4. 6944
    “…Importin α3 (Gene: Kpna3, the ortholog of human Importin α4) is a member of the importin α family and participates in nucleocytoplasmic transport by forming trimeric complexes between cargo proteins and importin β1. …”
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    Importin α3 (KPNA3) Deficiency Augments Effortful Reward-Seeking Behavior in Mice
  5. 6945
    “…BACKGROUND: Osteoarthritis (OA) is a common degenerative joint disease that may be closely linked to inflammation and oxidative stress destroying the balance of cartilage matrix. Theaflavin-3,3′-digallate (TFDG), a natural substance derived from black tea, has been reported to restrict the activity of inflammatory cytokines and effectively eliminate reactive oxygen species (ROS) in various diseases. …”
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    Theaflavin-3,3′-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways
  6. 6946
    “…METHODS: Eighty‐three eyes of 83 consecutive treatment naïve patients with stage 3 MNV3 were enrolled. …”
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    The RAP study, report 3: Discoloration of the macular region in patients with macular neovascularization type 3
  7. 6947
    “…In this research, a series of 3-(pyridine-3-yl)-2-oxazolidinone derivatives was designed, synthesized, and evaluated for in vitro antibacterial activity, which included bacteriostatic, morphological, kinetic studies, and molecular docking. …”
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    Synthesis and Biological Evaluation of 3-(Pyridine-3-yl)-2-Oxazolidinone Derivatives as Antibacterial Agents
  8. 6948
    “…LC–HRESIMS analysis showed different bioactive compounds in both active fractions (F2 and F3), including five polyenic macrolactams (kenalactams A-E), three isoflavone metabolites, along with mitomycin C and one p-phenyl derivative. …”
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    Taxonomic Characterization, Antiviral Activity and Induction of Three New Kenalactams in Nocardiopsis sp. CG3
  9. 6949
    por Lu, Yuanyuan
    Publicado 2022
    “…BACKGROUND: The earlier research has shown that the 14-3-3ζ is increased in neurofibrillary tangles (NFTs) of human Alzheimer's disease (AD) brains and stimulates the tau phosphorylation. …”
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    Early increase of cerebrospinal fluid 14-3-3ζ protein in the alzheimer's disease continuum
  10. 6950
    “…Recent studies in human pathology have demonstrated loss of trimethylation at lysine 27 of histone 3 (H3K27me3) in a subset of MNSTs using immunohistochemistry. …”
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    Loss of H3K27me3 expression in canine nerve sheath tumors
  11. 6951
    “…OBJECTIVES: To explore the clinical value of three-dimensional (3D) reconstruction technology combined with 3D printing in the treatment of pectus excavatum (PE). …”
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    Application of three-dimensional reconstruction technology combined with three-dimensional printing in the treatment of pectus excavatum
  12. 6952
    “…VAMP3 shRNA transduction considerably decreased VAMP3 expression compared with non-target shRNA-transduced (NT) cells. …”
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    Multifunctional regulation of VAMP3 in exocytic and endocytic pathways of RBL-2H3 cells
  13. 6953
    “…3-Hydroxybutyrate (3HB) is a product of interest as it is a precursor to the commercially produced bioplastic polyhydroxybutyrate. …”
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    Acetogenic production of 3-Hydroxybutyrate using a native 3-Hydroxybutyryl-CoA Dehydrogenase
  14. 6954
    “…[Image: see text] A straightforward, efficient, and selective method for the preparation of novel boryl-functionalized enynes or dienes via [Pt(PPh(3))(4)]-catalyzed diboration of a broad spectrum of symmetrical and unsymmetrical 1,3-diynes was developed. …”
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    [Pt(PPh(3))(4)]-Catalyzed Selective Diboration of Symmetrical and Unsymmetrical 1,3-Diynes
  15. 6955
    “…Reaction of a new two-coordinate iron complex, Fe{N((t)Bu)Dipp}(2) (1, Dipp = 2,6-diisopropylphenyl), with mesitylazide (MesN(3)) afforded a three-coordinate Fe–imidyl complex, Fe{N((t)Bu)Dipp}(2)([double bond, length as m-dash]NMes) (2). …”
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    Stabilization of a high-spin three-coordinate Fe(iii) imidyl complex by radical delocalization
  16. 6956
    “…(Tyr201Ter) and c.661C > T;p.(Arg221Cys) in CHST3 (NM_004273.5) in the three families with eight, five and two affected individuals, respectively. …”
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    Biallelic variants in CHST3 cause Spondyloepiphyseal dysplasia with joint dislocations in three Pakistani kindreds
  17. 6957
    “…Specifically, we identified and characterized a novel short isoform of Roundabout Guidance Receptor 3 (ROBO3s), upregulated in BLBC in response to chemotherapy and encoding for a protein variant lacking the transmembrane domain. …”
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    ROBO3s: a novel ROBO3 short isoform promoting breast cancer aggressiveness
  18. 6958
    por Li, Dechuan, Zhu, Guangping
    Publicado 2022
    “…Highly efficient quantum cutting KY(CO(3))(2):Tb(3+) phosphors excited by ultraviolet B (UVB) and ultraviolet C (UVC) were investigated. …”
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    Quantum Cutting in Ultraviolet B-Excited KY(CO(3))(2):Tb(3+) Phosphors
  19. 6959
    “…K/BxN serum-induced arthritis was induced in Wild-type (WT) and TET3 heterozygous-deficient (TET3(+/−)) C57BL/6 mice. …”
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    Role of DNA dioxygenase Ten-Eleven translocation 3 (TET3) in rheumatoid arthritis progression
  20. 6960
    “…Splicing of the GRB2 gene produces a deletion variant, Grb3-3, that is incapable of binding to RTKs. We show that, despite maintaining the ability to bind to Sos, the Grb3-3-Sos complex remains in the cytoplasm, unable to engage with RAS. …”
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    The Grb2 splice variant, Grb3-3, is a negative regulator of RAS activation
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