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  1. 7201
    “…The PRC2-associated histone modification, H3K27me3, increased at many of these sites. Our data support a dynamic interaction between two fundamental modes of epigenetic repression during postnatal maturation of excitatory neurons, which together confer robustness on neuronal regulation.…”
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    Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3
  2. 7202
    “…Glycogen synthase kinase 3β (GSK-3β) catalyses the hyperphosphorylation of tau protein in the Alzheimer’s disease (AD) pathology. …”
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    Synthesis and biological evaluation of thieno[3,2-c]pyrazol-3-amine derivatives as potent glycogen synthase kinase 3β inhibitors for Alzheimer’s disease
  3. 7203
    “…In this research, different films made of biodegradable polymers, poly(3-hydroxybutyrate) (PHB) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHB-co-HV), containing different molecular weights, with microstructured surfaces were investigated. …”
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    Honeycomb-Structured Porous Films from Poly(3-hydroxybutyrate) and Poly(3-hydroxybutyrate-co-3-hydroxyvalerate): Physicochemical Characterization and Mesenchymal Stem Cells Behavior
  4. 7204
    “…Perovskite La(2/3x)Li(3x)TiO(3) (LLTO) materials are promising solid-state electrolytes for lithium metal batteries (LMBs) due to their intrinsic fire-resistance, high bulk ionic conductivity, and wide electrochemical window. …”
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    Engineered interfaces between perovskite La(2/3x)Li(3x)TiO(3) electrolyte and Li metal for solid-state batteries
  5. 7205
    “…Acute stress increases hypothalamic CRF and the GABAergic neurosteroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP). We previously showed that 3α,5α-THP regulation of CRF is sex and brain region dependent. …”
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    (3α,5α)3-Hydroxypregnan-20-one (3α,5α-THP) Regulation of the HPA Axis in the Context of Different Stressors and Sex
  6. 7206
    “…The well-known compound tetrakis(tert-butylammonium)-cyclo-tetrametavanadate (V), [(CH(3))(3)CNH(3)](4)[V(4)O(12)] (1h_RT), which crystallizes in the tetragonal I4/m space group, undergoes an irreversible solid state transformation upon heating, constituting one of the few examples in which the initial and the final stages are structurally characterized by sc-XRD. …”
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    Reversible First-Order Single Crystal to Single Crystal Thermal Phase Transition in [(CH(3))(3)CNH(3)](4)[V(4)O(12)]
  7. 7207
    “…Mechanistically, SH3BGRL can unexpectedly bind to ribosomal subunits to enhance PIK3C3 translation efficiency and sustain ATG12 stability. …”
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    Adaptor SH3BGRL drives autophagy-mediated chemoresistance through promoting PIK3C3 translation and ATG12 stability in breast cancers
  8. 7208
    “…Differential expression Excel tables (one for each time point) were generated displaying average differential expression (log2 fold change) of the 4 replicates of treated versus control samples with cutoffs of 0.3 log2 fold change (increase or decrease) and p-values of less than 0.05. …”
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    Dataset of transcriptomic changes that occur in human preadipocytes over a 3-day course of exposure to 3,3′,4,4′,5-Pentachlorobiphenyl (PCB126)
  9. 7209
    “…Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) with various 3-hydroxyvalerate (3HV) contents biosynthesized by mixed microbial consortia (MMC) fed fermented dairy manure at the large-scale level was assessed over a 3-month period. …”
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    Effect of 3-Hydroxyvalerate Content on Thermal, Mechanical, and Rheological Properties of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Biopolymers Produced from Fermented Dairy Manure
  10. 7210
    “…Herein, focusing on the Fe(2)O(3) catalyst for the selective catalytic reduction of NO with NH(3) (NH(3)-SCR) as a model system, we reveal quantitatively the self-evolving Fe(3+)@Fe(2+) (∼1:1) double-centers under the in-situ condition by the first-principles microkinetic simulations, which enables the accurate prediction of the optimal industry operating temperature (590 K). …”
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    Activity Self-Optimization Steered by Dynamically Evolved Fe(3+)@Fe(2+) Double-Center on Fe(2)O(3) Catalyst for NH(3)-SCR
  11. 7211
    “…In this study, we aim to investigate the biological function of USP1 in osteoblastic MC3T3-E1 cells. METHODS: Hydrogen peroxide (H(2)O(2)) as an oxidative reagent was used to trigger osteoblastic MC3T3-E1 cellular damage. …”
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    USP1 Inhibits NF-κB/NLRP3 Induced Pyroptosis through TRAF6 in Osteoblastic MC3T3-E1 Cells
  12. 7212
    “…The glycolytic enzyme, pyruvate kinase Pyk1 maintains telomere heterochromatin by phosphorylating histone H3T11 (H3pT11), which promotes SIR (silent information regulator) complex binding at telomeres and prevents autophagy-mediated Sir2 degradation. …”
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    SESAME-catalyzed H3T11 phosphorylation inhibits Dot1-catalyzed H3K79me3 to regulate autophagy and telomere silencing
  13. 7213
    “…Experimental and theoretical studies on the reaction between (E)-3,3,3-trichloro-1-nitroprop-1-ene and N-(4-bromophenyl)-C-arylnitrylimine were performed. …”
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    On the Question of the Formation of Nitro-Functionalized 2,4-Pyrazole Analogs on the Basis of Nitrylimine Molecular Systems and 3,3,3-Trichloro-1-Nitroprop-1-Ene
  14. 7214
    “…The interaction between lentil protein isolate (LPI) and cyanidin-3-O-glucoside (C3G) was investigated via with UV–vis spectroscopy, circular dichroism, and fluorescence spectroscopy and the stability of anthocyanin was also evaluated. …”
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    The Interactional Characterization of Lentil Protein Isolate (LPI) with Cyanidin-3-O-Glucoside (C3G) and Their Effect on the Stability and Antioxidant Activity of C3G
  15. 7215
    “…Herein, we performed terahertz time-domain spectroscopy (THz-TDS) in the frequency range of 0.1–3.0 THz on different thicknesses of MAPbBr(3) (0.3, 0.6, and 0.8 mm) and MAPbI(3) (0.6, 0.8, 0.9, 1.3, and 2.3 mm). …”
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    Measurement of Optical Properties of CH(3)NH(3)PbX(3) (X = Br, I) Single Crystals Using Terahertz Time-Domain Spectroscopy
  16. 7216
    “…During these years, the 3D node coverage of heterogeneous wireless sensor networks that are closer to the actual application environment has become a strong focus of research. …”
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    VKECE-3D: Energy-Efficient Coverage Enhancement in Three-Dimensional Heterogeneous Wireless Sensor Networks Based on 3D-Voronoi and K-Means Algorithm
  17. 7217
    “…Here, we show that BRPF1, a multi-histone binding module protein, is essential for pluripotency in human embryonic stem cells (ESCs). BRPF1, H3K4me3, and H3K23ac substantially co-occupy the open chromatin and stemness genes in hESCs. …”
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    BRPF1 bridges H3K4me3 and H3K23ac in human embryonic stem cells and is essential to pluripotency
  18. 7218
    “…Acute myeloid leukemia (AML) patients with FLT3-ITD mutations are associated with poor prognosis. …”
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    The GSK3β/Mcl-1 axis is regulated by both FLT3-ITD and Axl and determines the apoptosis induction abilities of FLT3-ITD inhibitors
  19. 7219
    “…We profiled genome-wide H3K27me3 and H3K27ac occupancy by CUT&Tag in neural tissues from ICR mouse embryos with benzo[a]pyrene (BaP)-induced NTDs (250 mg kg(−1)) at E9.5. …”
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    Distinct H3K27me3 and H3K27ac Modifications in Neural Tube Defects Induced by Benzo[a]pyrene
  20. 7220
    “…Although we found that all three APOBEC3s could interact with APOBEC3H haplotype I, only APOBEC3F affected APOBEC3H haplotype I by surprisingly accelerating its proteasomal degradation. …”
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    Stability of APOBEC3F in the Presence of the APOBEC3 Antagonist HIV-1 Vif Increases at the Expense of Co-Expressed APOBEC3H Haplotype I
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