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  1. 7461
    “…Seventeen novel 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylate and -carboxamide derivatives were synthesized and evaluated for their growth inhibition in seven human solid tumor and a human leukemia HL-60 cell lines. …”
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    Synthesis and Antitumor Activity of 3-Methyl-4-oxo-3,4-dihydroimidazo [5,1-d][1,2,3,5]tetrazine-8-carboxylates and -carboxamides
  2. 7462
    “…Expression of the PTP4A3 gene, encoding a phosphatase, is predictive of poor patient survival. …”
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    Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) promotes the aggressiveness of human uveal melanoma through dephosphorylation of CRMP2
  3. 7463
    “…INTERPRETATION: We identify a new pro-oncogenic mechanism whereby 14-3-3θ negatively regulates the nuclear function of the tumor suppressor SLC2A4RG, with significant therapeutic implications for the intervention of human glioma. …”
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    Shuttling SLC2A4RG is regulated by 14-3-3θ to modulate cell survival via caspase-3 and caspase-6 in human glioma
  4. 7464
    “…The degree of Zn(2+) and Ta(5+) ions ordering could play an important role in the dielectric loss in Ba(Zn(1/3)Ta(2/3))O(3) (BZT) ceramics. However, the influence of the grain size of Ba(B′(1/3)B″(2/3))O(3) ceramics with nano or sub-micron grains on the ordering domains structure is still not clear. …”
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    Ordered Domains and Microwave Properties of Sub-micron Structured Ba(Zn(1/3)Ta(2/3))O(3) Ceramics Obtained by Spark Plasma Sintering
  5. 7465
    “…CXCR3 was up-regulated on effector CD4(+)Foxp3(−) T cells as well as Foxp3(+) Tregs. …”
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    Plasmodium chabaudi AS Infection Induces CD4(+) Th1 Cells and Foxp3(+)T-bet(+) Regulatory T Cells That Express CXCR3 and Migrate to CXCR3 Ligands
  6. 7466
    “…The detailed function and molecular mechanism of miR-214-3p in adipocyte development is unclear. In this study, the 3T3-L1 cell line was used to analyze the function of miR-214-3p in vitro. …”
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    MicroRNA-214-3p Targeting Ctnnb1 Promotes 3T3-L1 Preadipocyte Differentiation by Interfering with the Wnt/β-Catenin Signaling Pathway
  7. 7467
    “…Therefore, the current study screened for miRNAs that regulate BLM gene expression, with software predicting that miRNA (miR)-27b-3p, miR-607, miR-361-3p, miR-628-5p and miR-338-3p. …”
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    miR-27b-3p and miR-607 cooperatively regulate BLM gene expression by directly targeting the 3′-UTR in PC3 cells
  8. 7468
    “…Compared with the non-catalytic ‘Zwitterion mechanism’, this Eley–Rideal model was proposed for CO(2) + RR′NH with MCO(3) (M = Ca, Mg, and Ba) with four elementary reaction steps: (B1) amine adsorption, (B2) Zwitterion formation, (B3) carbamate formation, and (B4) carbamate desorption. …”
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    Eley–Rideal model of heterogeneous catalytic carbamate formation based on CO(2)–MEA absorptions with CaCO(3), MgCO(3) and BaCO(3)
  9. 7469
    “…Using in vitro cell cultures of preosteoblastic MC3T3‐E1 cells, we found that TNF‐α inhibited osteoblastic differentiation accompanied by an increase in ELP2 expression and STAT3 activation. …”
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    ELP2 negatively regulates osteoblastic differentiation impaired by tumor necrosis factor α in MC3T3–E1 cells through STAT3 activation
  10. 7470
    “…Ceramics of Sr(1−x)Pr(2x/3)□(x)(/3)TiO(3) (x = 0.1–1.0) were prepared by solid-state reaction at 1700–1723 K using highly reducing atmospheres. …”
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    Enhancing the thermoelectric properties of Sr(1−x)Pr(2x/3)□(x)(/3)TiO(3±δ) through control of crystal structure and microstructure
  11. 7471
    “…Mechanistically, the interaction of lncRNA RP11-732M18.3 with 14-3-3β/α increases the degradation of the p21 protein. lncRNA RP11-732M18.3 promoted the recruitment of ubiquitin-conjugating enzyme E2 E1 to 14-3-3β/α and the binding of 14-3-3β/α with ubiquitin-conjugating enzyme E2 E1 (UBE2E1) promoted the degradation of p21. …”
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    The binding of lncRNA RP11-732M18.3 with 14-3-3 β/α accelerates p21 degradation and promotes glioma growth
  12. 7472
    “…[Image: see text] A one-pot synthesis of 2-(het)aryl/alkyl-3-cyanobenzofurans has been reported. The overall sequence involves base-induced reaction of 2-(2-bromoaryl)-3-(het)aryl-3-(methylthio)acrylonitriles with benzyl carbamate, generating α-(het)aroyl-α-(2-bromoaryl)acetonitriles, which are in situ subjected to copper-catalyzed intramolecular O-arylation, furnishing the 2-(het)aryl/alkyl-3-cyanobenzofurans in high yields. …”
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    One-Pot Synthesis of 2-(Het)aryl/alkyl-3-cyanobenzofurans from 2-(2-Bromoaryl)-3-(het)aryl-3-(methylthio)acrylonitriles and Benzyl Carbamate
  13. 7473
    “…The complexes Ag(L)(n)[WCA] (L=P(4)S(3), P(4)Se(3), As(4)S(3), and As(4)S(4); [WCA]=[Al(OR(F))(4)](−) and [F{Al(OR(F))(3)}(2)](−); R(F)=C(CF(3))(3); WCA=weakly coordinating anion) were tested for their performance as ligand‐transfer reagents to transfer the poorly soluble nortricyclane cages P(4)S(3), P(4)Se(3), and As(4)S(3) as well as realgar As(4)S(4) to different transition‐metal fragments. …”
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    Coordination Chemistry of P(4)S(3) and P(4)Se(3) towards the Iron Fragments [Fe(Cp)(CO)(2)](+) and [Fe(Cp)(PPh(3))(CO)](+)
  14. 7474
    “…Crosslinked sulfonated polyacrylamide (Cross-PAA-SO(3)H) attached to nano-Fe(3)O(4) as a superior catalyst has been used for the synthesis of 3-alkyl-4-phenyl-1,3-thiazole-2(3H)-thione derivatives through a three-component reactions of phenacyl bromide or 4-methoxyphenacyl bromide, carbon disulfide and primary amine under reflux condition in ethanol. …”
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    Crosslinked sulfonated polyacrylamide (Cross-PAA-SO(3)H) tethered to nano-Fe(3)O(4) as a superior catalyst for the synthesis of 1,3-thiazoles
  15. 7475
    “…However, when the Sb(2)S(3) thickness is larger than the hole diffusion length, the inferior area in Sb(2)S(3) for holes that cannot be diffused to P3HT would become a dominant factor affecting the photocurrent. …”
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    Sb(2)S(3) Thickness-Related Photocurrent and Optoelectronic Processes in TiO(2)/Sb(2)S(3)/P3HT Planar Hybrid Solar Cells
  16. 7476
    “…Loss‐ and gain‐of‐function experiments demonstrate that miR‐193a‐3p regulates the MAPK pathway by targeting the MAP3k3 gene. …”
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    The miR‐193a‐3p‐MAP3k3 Signaling Axis Regulates Substrate Topography‐Induced Osteogenesis of Bone Marrow Stem Cells
  17. 7477
    “…CCK-8 analysis showed that puerarin (0.1, 1 and 10 µM) promoted the viability of osteoblastic MC3T3-E1 cells, with 1 µM of puerarin exhibiting the strongest effect. …”
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    Puerarin promotes the viability and differentiation of MC3T3-E1 cells by enhancing LC3B-mediated autophagy through downregulation of miR-204
  18. 7478
    “…Here, we determined that the protein tyrosine phosphatase 4A3 (PTP4A3 or PRL-3) plays a critical role in T-ALL initiation and progression by promoting leukemia cell migration. …”
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    Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) drives migration and progression of T-cell acute lymphoblastic leukemia in vitro and in vivo
  19. 7479
    “…RNAi-mediated downregulation of P300 modulated the global acetylation of H3 and the acetylation of H3K4, H3K9, and H3K27 in gata4 and Tbx5 promoters. …”
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    Acetylation of H3K4, H3K9, and H3K27 mediated by p300 regulates the expression of GATA4 in cardiocytes
  20. 7480
    “…The structure of the title quinoline carboxamide derivative, C(26)H(25)N(3)O, is described. The quinoline moiety is not planar as a result of a slight puckering of the pyridine ring. …”
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    The synthesis, crystal structure and Hirshfeld analysis of 4-(3,4-di­methyl­anilino)-N-(3,4-di­methyl­phen­yl)quinoline-3-carboxamide
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