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7641
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7642por Ahmed, Mona Mostafa, Hegazy, Abdelmonem Awad, Embaby, Ahmed, Nawwar, Esraa Mohammad, Hegazy, Salwan Abdelmonem, Ibrahim, Hanaa M., Gobran, Mai Ahmed“…The study aimed to evaluate the diagnostic utility of TOX, FOXP3, CDD4 and GATA3 in differentiating early stages of MF from histologically overlapping BID lesions. …”
Publicado 2023
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7643por Han, Dongsheng, Schaffner, Samantha H., Davies, Jonathan P., Benton, Mary Lauren, Plate, Lars, Nordman, Jared T.“…Depletion of the chromatin-binding protein BRWD3 (Bromodomain and WD repeat-containing protein 3), a known substrate-specificity factor of the Cul4-DDB1 E3 ubiquitin ligase complex, results in increased H3K4me1 (H3 lysine 4 monomethylation) levels. …”
Publicado 2023
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7644por Navarro, Rosa E., Coronado, Alan, Inoue, Motomichi, Orozco Valencia, Ángel U., Soberanes, Yedith, Salazar-Medina, Alex J.“…[Image: see text] A new macrocyclic ligand was synthesized by a reaction between diethylenetriaminepentaacetic (DTPA) dianhydride and trans-1,4-diaminocyclohexane, and the Gd(III) and Yb(III) complexes were prepared. The compounds were characterized by spectroscopic methods. …”
Publicado 2023
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7645por Othman, Jad, Potter, Nicola, Mokretar, Katya, Taussig, David, Khan, Anjum, Krishnamurthy, Pramila, Latif, Anne-Louise, Cahalin, Paul, Aries, James, Amer, Mariam, Belsham, Edward, Conneally, Eibhlin, Craddock, Charles, Culligan, Dominic, Dennis, Mike, Duncan, Caroline, Freeman, Sylvie D., Furness, Caroline, Gilkes, Amanda, Gkreka, Paraskevi, Hodgson, Katherine, Ingram, Wendy, Jain, Manish, King, Andrew, Knapper, Steven, Kottaridis, Panagiotis, McMullin, Mary Frances, Mohite, Unmesh, Ngu, Loretta, O’Nions, Jenny, Patrick, Katharine, Rider, Tom, Roberts, Wing, Severinsen, Marianne Tang, Storrar, Neill, Taylor, Tom, Russell, Nigel H., Dillon, Richard“…Patients with FLT3-mutated AML have a high relapse rate and suboptimal outcomes. …”
Publicado 2023
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7646por Takyar, Shervin S.Enlace del recurso
Publicado 2023
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7647por Ashokan, Agalya, Nehru, Jayasudha, Chakkarapani, Nandhini, Khamrang, Themmila, Kavitha, Savaridasan Jose, Rajakannan, Venkatachalam, Hemamalini, Madhukar“…In the title hydrated salt, C(5)H(5)Cl(2)N(2) (+)·C(6)H(4)NO(3) (−)·H(2)O, the pyridine N atom of the cation is protonated and an intramolecular O—H⋯O hydrogen bond is observed in the anion, which generates an S(6) ring. …”
Publicado 2023
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7648por Yuyama, Yoshihiko, Kawamura, Tomoyuki, Hotta, Yuko, Nishikawa-Nakamura, Naoko, Hamazaki, Takashi“…Among these phenotypes, MODY3, caused by mutations in HNF1A, is one of the most frequent. …”
Publicado 2023
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7649“…To address these challenges, in this paper we propose an online learning status recognition method based on shallow 3D convolution (S3DC-OLSR) for online students, to identify students' online learning states by analysing their micro-expressions. …”
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7650“…Also, novel indenopyridotriazine [4.3.3]propellanes were synthesized via the reaction of pyrido[1,2,4]triazine and N-methyl-1-(methylthio)-2-nitroethenamine (NMSM) by using of HOAc in ethanol. …”
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7651por Kiladjian, Jean-Jacques, Vannucchi, Alessandro M., Gerds, Aaron T., Gupta, Vikas, Verstovsek, Srdan, Egyed, Miklos, Platzbecker, Uwe, Mayer, Jiří, Grosicki, Sebastian, Illés, Árpád, Woźny, Tomasz, Oh, Stephen T., McLornan, Donal, Kirgner, Ilya, Yoon, Sung-Soo, Harrison, Claire N., Klencke, Barbara, Huang, Mei, Kawashima, Jun, Mesa, Ruben“…Post hoc analyses herein evaluated the efficacy and safety of momelotinib in patients with MF and thrombocytopenia (platelet counts <100 × 10(9)/L) from randomized phase 3 studies: MOMENTUM (momelotinib versus danazol; JAK inhibitor experienced); SIMPLIFY-1 (momelotinib versus ruxolitinib; JAK inhibitor naïve); and SIMPLIFY-2 (momelotinib versus best available therapy; JAK inhibitor experienced); these studies were not statistically powered to assess differences in thrombocytopenic subgroups, and these analyses are descriptive. …”
Publicado 2023
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7652por Zhang, Chuancheng, Ding, Shoujun, Wang, Miaomiao, Ren, Hao, Tang, Xubing, Zou, Yong, Dou, Renqin, Liu, Wenpeng“…In this study, a high-quality 5 at% Yb(3+) and 1 at% Ho(3+) co-doped Gd(0.74)Y(0.2)TaO(4) single crystal was grown by the Czochralski (Cz) method, and the structure of the as-grown crystal was characterized. …”
Publicado 2023
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7653“…MATERIALS AND METHODS: SF/Col-Ⅱ/HA scaffolds were constructed by low-temperature 3D printing, and to prepare a three-phase complex. …”
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7654por Belda-Perez, Ramses, Heras, Sonia, Cimini, Costanza, Romero-Aguirregomezcorta, Jon, Valbonetti, Luca, Colosimo, Alessia, Colosimo, Bianca Maria, Santoni, Silvia, Barboni, Barbara, Bernabò, Nicola, Coy, Pilar“…All the 3D-printed scaffolds were used to support IVF process in a bovine embryo assay. …”
Publicado 2023
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7655por Chang, Jeeyoon, Shin, Min-Kyung, Park, Joori, Hwang, Hyun Jung, Locker, Nicolas, Ahn, Junhak, Kim, Doyeon, Baek, Daehyun, Park, Yeonkyoung, Lee, Yujin, Boo, Sung Ho, Kim, Hyeong-In, Kim, Yoon Ki“…The direct interaction between eIF4A3-eIF3g serves as a molecular linker between the eIF4A3 and eIF3 complex, thereby facilitating internal ribosomal entry. …”
Publicado 2023
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7656por Li, Shuai, Leakey, Andrew D. B., Moller, Christopher A., Montes, Christopher M., Sacks, Erik J., Lee, DoKyoung, Ainsworth, Elizabeth A.“…The deleterious effects of ozone (O(3)) pollution on crop physiology, yield, and productivity are widely acknowledged. …”
Publicado 2023
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7657por Mestre-Fos, Santi, Ferguson, Lucas, Trinidad, Marena, Ingolia, Nicholas T., Cate, Jamie H. D.“…Our data reveal eIF3 predominantly interacts with 3’ untranslated region (3’-UTR) termini of multiple mRNA isoforms, adjacent to the poly(A) tail. …”
Publicado 2023
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7658por Wadden, Thomas A., Chao, Ariana M., Machineni, Sriram, Kushner, Robert, Ard, Jamy, Srivastava, Gitanjali, Halpern, Bruno, Zhang, Shuyu, Chen, Jiaxun, Bunck, Mathijs C., Ahmad, Nadia N., Forrester, Tammy“…The coprimary endpoint of the percentage of participants achieving additional weight reduction ≥5% was met with 87.5% (s.e. 2.2) with tirzepatide and 16.5% (s.e. 3.0) with placebo achieving this threshold (odds ratio 34.6%; 95% CI 19.2%, 62.6%; P < 0.001). …”
Publicado 2023
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7659Exposure to Chlorpyrifos Alters Proliferation, Differentiation and Fatty Acid Uptake in 3T3-L1 Cellspor Czajka, Magdalena, Sawicki, Krzysztof, Matysiak-Kucharek, Magdalena, Kruszewski, Marcin, Kurzepa, Jacek, Wojtyła-Buciora, Paulina, Kapka-Skrzypczak, Lucyna“…The aim of this study was to investigate the effect of a representative of OPs, chlorpyrifos (CPF), on viability, proliferation, differentiation, and fatty acid uptake in 3T3-L1 cells. The effect of CPF exposure on preadipocyte proliferation was examined by the MTT, NR, and BrdU assays. …”
Publicado 2023
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7660“…To investigate the effects of cimifugin on adipogenesis and tumor necrosis factor (TNF-α)-induced insulin resistance (IR) and inflammation in 3T3-L1 adipocytes. 3T3-L1 adipocytes were treated with 3-isobutyl-1-methyl-xanthine, dexamethasone, and insulin or cimifugin and then Oil Red O staining and intracellular triglyceride content detection were performed to assess adipogenesis. …”
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