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8121por Kim, In-Ryoung, Kim, Seong-Eon, Baek, Hyun-Su, Kim, Bok-Joo, Kim, Chul-Hoon, Chung, In-Kyo, Park, Bong-Soo, Shin, Sang-Hun“…It also increased the expression of the autophagy-related factors beclin-1, SQSTM1/p62 and the conversion of LC3-II from LC3-I. The application of 3-MA decreased the activity of ALP and the autophagy induced by kaempferol. …”
Publicado 2016
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8122“…RESULTS: Three-dimensional (3D) reconstruction revealed latent features of carious hard tissues (strongly expressed amelogenin proteins in dentin tubules), and soft tissues (increased glial markers GFAP and S100B in pulp components). …”
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8123por Yoo, Jung-Yoon, Jeong, Jae-Wook, Fazleabas, Asgerally T., Tayade, Chandrakant, Young, Steven L., Lessey, Bruce A.“…Our objective is to determine how STAT3 activity is regulated in endometriosis. Protein inhibitor of activated STAT3 (PIAS3) is a negative regulator of STAT3 activity. …”
Publicado 2016
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8124por Frampton, Matthew, da Silva Filho, Miguel Inacio, Broderick, Peter, Thomsen, Hauke, Försti, Asta, Vijayakrishnan, Jayaram, Cooke, Rosie, Enciso-Mora, Victor, Hoffmann, Per, Nöthen, Markus M, Lloyd, Amy, Holroyd, Amy, Eisele, Lewin, Jöckel, Karl-Heinz, Ponader, Sabine, von Strandmann, Elke Pogge, Lightfoot, Tracy, Roman, Eve, Lake, Annette, Montgomery, Dorothy, Jarrett, Ruth F, Swerdlow, Anthony J, Engert, Andreas, Hemminki, Kari, Houlston, Richard S“…A combined analysis identifies new HL susceptibility loci mapping to 3p24.1 (rs3806624; P=1.14×10(-12), odds ratio [OR]=1.26) and 6q23.3 (rs7745098; P=3.42×10(-9), OR=1.21). rs3806624 localizes 5’ to the EOMES (eomesodermin) gene within a p53 response element affecting p53 binding. rs7745098 maps intergenic to HBS1L and MYB, a region previously associated with hematopoiesis. …”
Publicado 2013
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8125por Slørdahl, Tobias S., Abdollahi, Pegah, Vandsemb, Esten N., Rampa, Christoph, Misund, Kristine, Baranowska, Katarzyna A., Westhrin, Marita, Waage, Anders, Rø, Torstein B., Børset, Magne“…PRL-3 has also been identified as a marker gene for a subgroup of patients with MM. …”
Publicado 2016
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8126por Hao, Feike, Itoh, Takashi, Morita, Eiji, Shirahama‐Noda, Kanae, Yoshimori, Tamotsu, Noda, Takeshi“…We previously reported that overexpression of phosphatase‐deficient MTMR3, a member of the myotubularin phosphatidylinositol (PI) 3‐phosphatase family, leads to induction of autophagy. …”
Publicado 2016
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8127por Gargaté, Maria João, Ferreira, Idalina, Vilares, Anabela, Martins, Susana, Cardoso, Carlos, Silva, Susana, Nunes, Baltazar, Gomes, João Paulo“…METHODS: We studied the seroprevalence trends in the Portuguese general population over the past 3 decades, by assessing chronological spread cross-sectional studies, with special focus on women of childbearing age, by age group, region and gender. …”
Publicado 2016
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8128por Bonartsev, A.P., Bonartseva, G. A., Myshkina, V. L., Voinova, V. V., Mahina, T. K., Zharkova, I. I., Yakovlev, S. G., Zernov, A. L., Ivanova, E. V., Akoulina, E. A., Kuznetsova, E. S., Zhuikov, V. A., Alekseeva, S. G., Podgorskii, V. V., Bessonov, I. V., Kopitsyna, M. N., Morozov, A. S., Milanovskiy, E. Y., Tyugay, Z. N., Bykova, G. S., Kirpichnikov, M. P., Shaitan, K. V.“…We studied the ability of an effective strain-producer Azotobacter chroococcum 7B to synthesize not only poly(3-hydroxybutyrate) homopolymer (PHB) and its main copolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), but also a novel copolymer, poly(3-hydroxybutyrate-co-3-hydroxy-4-methylvalerate) (PHB4MV). …”
Publicado 2016
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8129por Robinson, Thomas P., Lo, Siu‐Kwan, De Rosa, Daniel, Aldridge, Simon, Goicoechea, Jose M.“…Despite their differing reactivity towards nucleophilic substrates with polarised element–hydrogen bonds (e.g., NH(3)), both the phosphorus(III), P(ONO) (1 a), and arsenic(III), As(ONO) (1 b), compounds exhibit similar reactivity towards charged nucleophiles and electrophiles. …”
Publicado 2016
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8130por Marzi, Carola, Holdt, Lesca M, Fiorito, Giovanni, Tsai, Pei-Chien, Kretschmer, Anja, Wahl, Simone, Guarrera, Simonetta, Teupser, Daniel, Spector, Tim D., Iacoviello, Licia, Sacerdote, Carlotta, Strauch, Konstantin, Lee, Serene, Thasler, Wolfgang E., Peters, Annette, Thorand, Barbara, Wolf, Petra, Prokisch, Holger, Tumino, Rosario, Gieger, Christian, Krogh, Vittorio, Panico, Salvatore, Bell, Jordana T., Matullo, Giuseppe, Waldenberger, Melanie, Grallert, Harald, Koenig, Wolfgang“…Four CpG sites (located at BCL3, AQP3, SOCS3, and cg19821297 intergenic at chromosome 19p13.2, P ≤ 1.01E-07) were significantly hypomethylated at high CRP concentrations independent of various confounders including age, sex, BMI, smoking, and white blood cell composition. …”
Publicado 2016
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8131por Wu, Yelin, Quan, Yanchun, Liu, Yuanqi, Liu, Keiwei, Li, Hongquan, Jiang, Ziwei, Zhang, Tian, Lei, Hu, Radek, Katherine A., Li, Dongqing, Wang, Zhenhua, Lu, Jilong, Wang, Wang, Ji, Shizhao, Xia, Zhaofan, Lai, Yuping“…Here we show that the antimicrobial protein REG3A controls TLR3-mediated inflammation after skin injury. …”
Publicado 2016
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8132por Gao, Yuan-Feng, Zhu, Tao, Mao, Chen-Xue, Liu, Zhi-Xiong, Wang, Zhi-Bin, Mao, Xiao-Yuan, Li, Ling, Yin, Ji-Ye, Zhou, Hong-Hao, Liu, Zhao-Qian“…Independent validation with glioma patients tissue (n = 70) and normal brain tissue (n = 19) found PPIC, EMP3 and CHI3L1 were up-regulated in glioma tissue. …”
Publicado 2016
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8133por Jiang, Dongqing, Wang, Dianhui, Zhuang, Xianghua, Wang, Zhanqing, Ni, Yihong, Chen, Shihong, Sun, Fudun“…RESULTS: TG content of differentiated 3T3-L1 cells was significantly decreased by more than 10% after treated with BBR. …”
Publicado 2016
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8134
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8135por McGarvey, Lorcan, Morice, Alyn H, Smith, Jaclyn A, Birring, Surinder S, Chuecos, Ferran, Seoane, Beatriz, Jarreta, Diana“…The efficacy of aclidinium bromide 400 µg twice daily in patients with stable COPD has been established in two phase III studies (ACCORD COPD I and ATTAIN) and a phase IIIb active-comparator study. …”
Publicado 2016
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8136por Paddison, Joseph A. M., Ong, Harapan S., Hamp, James O., Mukherjee, Paromita, Bai, Xiaojian, Tucker, Matthew G., Butch, Nicholas P., Castelnovo, Claudio, Mourigal, Martin, Dutton, S. E.“…Neutron-scattering and bulk thermomagnetic measurements reveal a phase transition at ∼0.3 K from a disordered spin-ice-like regime to an emergent charge ordered state, in which emergent magnetic charge degrees of freedom exhibit three-dimensional order while spins remain partially disordered. …”
Publicado 2016
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8137por Kobayashi, Minoru, Funayama, Ryo, Ohnuma, Shinobu, Unno, Michiaki, Nakayama, Keiko“…Knockdown of the pathway components transcription factor 7‐like 2 (TCF7L2) or β‐catenin thus increased ABCC3 expression, whereas activation of Wnt signaling with inhibitors of glycogen synthase kinase–3β (GSK‐3β) reduced it. …”
Publicado 2016
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8138Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity“…We demonstrate that forced apical localization of Par3, which is normally restricted to tight junctions, is sufficient to alter apical membrane identity through its interactions with phosphatidylinositol 3-kinase (PI3K) and the Rac1 guanine nucleotide exchange factor Tiam1. …”
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8139por Kieckhaefer, Julia E., Lukovac, Sabina, Ye, Diana Z., Lee, Dolim, Beetler, Danielle J., Pack, Michael, Kaestner, Klaus H.“…Here, we studied the role of Polr3b, a large RNA polymerase III subunit, in the mammalian intestinal epithelium. …”
Publicado 2016
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8140“…3D integration with through-silicon via (TSV) is a promising candidate to perform system-level integration with smaller package size, higher interconnection density, and better performance. …”
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