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8181por Sijbesma, Eline, Skora, Lukasz, Leysen, Seppe, Brunsveld, Luc, Koch, Uwe, Nussbaumer, Peter, Jahnke, Wolfgang, Ottmann, Christian“…The two pockets that these fragments occupy are part of at least three physiologically relevant and structurally characterized 14-3-3 PPI interfaces, including those with serotonin N-acetyltransferase and plant transcription factor FT. …”
Publicado 2017
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8182por Zou, Bingyu, Wang, Hailian, Liu, Yilong, Qi, Ping, Lei, Tiantian, Sun, Minghan, Wang, Yi“…This study aimed to determine the apoptosis-inducing effect of mangiferin on human ovarian carcinoma OVCAR3 cells. By in vitro studies, we found mangiferin significantly inhibited viability of OVCAR3 cells, and remarkably increased the sensitivity of OVCAR3 cells to cisplatin. …”
Publicado 2017
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8183por Hamed, Sonja, Behnes, Michael, Pauly, Dominic, Lepiorz, Dominic, Barre, Max, Becher, Tobias, Lang, Siegfried, Akin, Ibrahim, Borggrefe, Martin, Bertsch, Thomas, Hoffmann, Ursula“…BACKGROUND: Pentraxin-3 (PTX-3) is an acute-phase protein involved in inflammatory and infectious processes. …”
Publicado 2017
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8184por Huang, Chao-Min, Chang, Kuo-Chin, Hung, Chao-Hung, Chiu, King-Wah, Lu, Sheng-Nan, Wang, Jing-Houng, Chen, Chien-Hung, Kee, Kwong-Ming, Kuo, Yuan-Hung, Tsai, Ming-Chao, Tseng, Po-Lin, Lin, Ming-Tsung, Wu, Cheng-Kun, Hu, Tsung-Hui, Cho, Chung-Lung, Yen, Yi-Hao“…In this study, then, we investigated the association of PNPLA3 and IFNL3 polymorphisms with HS in Asian CHC patients. …”
Publicado 2017
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8185“…Here we describe how a family of adaptor proteins called 14-3-3s can be targeted using small molecule drugs to enhance axon outgrowth and regeneration. 14-3-3s bind to many functionally diverse client proteins to regulate their functions. …”
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8186Three-dimensional structure of the 3′X-tail of hepatitis C virus RNA in monomeric and dimeric states“…Using small angle X-ray scattering measurements combined with model building guided by NMR spectroscopy, we have studied the stoichiometry, structure, and flexibility of domain 3′X and two smaller subdomain sequences as a function of ionic strength, and obtained a three-dimensional view of the full-length domain in its monomeric and dimeric states. …”
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8187por Tan, Yuyong, Ci, Yanpeng, Dai, Xiangpeng, Wu, Fei, Guo, Jianping, Liu, Deliang, North, Brian J., Huo, Jirong, Zhang, Jinfang“…Furthermore, we demonstrated that Cullin 3-based ubiquitin E3 ligase(s) primarily reduced the stability of HDAC6. …”
Publicado 2017
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8188por Duan, Ran, Liang, Junrong, Zhang, Jing, Chen, Yuhuang, Wang, Jing, Tong, Jing, Guo, Bangcheng, Hu, Wanfu, Wang, Mingliu, Zhao, Jiayong, Liu, Chang, Hao, Huijing, Wang, Xin, Jing, Huaiqi“…Prevalence of pathogenic bioserotype 3/O:3 varied geographically. In this population, the presence of fecal leukocytes was a characteristic of Y. enterocolitica infection and should be used as an indication for microbiological diagnostic testing, rather than for the diagnosis of bacillary dysentery. …”
Publicado 2017
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8189por Singh, Sarika, Prestat, Eric, Huang, Liang-Feng, Rondinelli, James M., Haigh, Sarah J., Rosen, Brian A.“…Solid phase crystallization offers an attractive route to synthesize Ni nanoparticles on a La(2)O(3) support. These materials have shown great promise as catalysts for methane oxidation and similar reactions. …”
Publicado 2017
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8190por Chang, Chia-Chu, Chen, Chen-Yu, Chang, Geen-Dong, Chen, Ting-Huan, Chen, Woan-Ling, Wen, Hui-Chin, Huang, Chih-Yang, Chang, Chung-Ho“…Effects of chronic exposure to hyperglycemia or AGEs on the adipogenic differentiation of 3T3-L1 preadipocytes remain unclear. We examined the chronic effect of AGEs and high glucose on the differentiation of 3T3-L1 cells by culturing 3T3-L1 cells in the presence of AGEs or 25 mM glucose for 1 month. …”
Publicado 2017
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8191por Matsumoto, Naoya, Satyam, Abhigyan, Geha, Mayya, Lapchak, Peter H., Dalle Lucca, Jurandir J., Tsokos, Maria G., Tsokos, George C.“…C3a is important in the regulation of the immune response as well as in the development of organ inflammation and injury. …”
Publicado 2017
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8192por Ueda, Yuko, Kitae, Kaori, Ooshio, Ikumi, Fusamae, Yasuyuki, Kawaguchi, Megumi, Jingushi, Kentaro, Harada, Kazuo, Hirata, Kazumasa, Tsujikawa, Kazutake“…Human AlkB homolog 3 (ALKBH3), a homolog of the Escherichia coli protein AlkB, demethylates 1-methyladenine and 3-methylcytosine (3-meC) in single-stranded DNA and RNA by oxidative demethylation. …”
Publicado 2016
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8193“…The aim of this study was to evaluate the effects of supplementary Cr3 {chromium(III) propionate complex, [Cr(3)O(O(2)CCH(2)CH(3))(6)(H(2)O)(3)]NO(3))} on the mineral status in female Wistar rats. …”
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8194“…Additionally, we extended the scope of the Huber et al. (2016) work by testing a broader age range, including children as young as 3 years, and using a culturally distinct participant pool. …”
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8195por Li, Yueru, Rong, Yinghui, Bao, Lisui, Nie, Ben, Ren, Guang, Zheng, Chen, Amin, Rajesh, Arnold, Robert D., Jeganathan, Ramesh B., Huggins, Kevin W.“…BACKGROUND: Increased consumption of omega-3 (ω-3) fatty acids found in cold-water fish and fish oil has been reported to protect against obesity. …”
Publicado 2017
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8196por Beaven, Robin, Bastos, Ricardo Nunes, Spanos, Christos, Romé, Pierre, Cullen, C. Fiona, Rappsilber, Juri, Giet, Régis, Goshima, Gohta, Ohkura, Hiroyuki“…We found that phosphodocking 14-3-3 proteins stabilize spindle bipolarity in Drosophila melanogaster oocytes. …”
Publicado 2017
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8197“…PfPSH3N also shows DNA helicase activity in the 3′–5′ direction. …”
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8198por Zhang, Bin, Gong, Aihua, Shi, Hui, Bie, Qingli, Liang, Zhaofeng, Wu, Peipei, Mao, Fei, Qian, Hui, Xu, Wenrong“…Growing evidence indicates that 14-3-3ζ and yes-associated protein (YAP) substantially promote tumorigenesis and tumor development. …”
Publicado 2017
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8199“…The enamine exchange with amines was efficiently catalyzed by Bi(OTf)(3) and Sc(OTf)(3) (2 mol %) and the equilibria (60 mm) could be attained within hours at room temperature. …”
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8200por Oh, Soo-Jin, Woo, Junsung, Lee, Young-Sun, Cho, Minhee, Kim, Eunju, Cho, Nam-Chul, Park, Jae-Yong, Pae, Ae Nim, Justin Lee, C., Hwang, Eun Mi“…RESULTS: We identified 14-3-3γ as novel binding partner of Best1 in astrocytes: among 7 isoforms of 14-3-3 protein, only 14-3-3γ was found to bind specifically. …”
Publicado 2017
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