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  1. 8361
    “…Demethylation with azacytidine in cultured sympathetic ganglia cells led to increased GATA3 expression, suggesting a mechanistic link between GATA3 expression and DNA methylation. …”
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    Epigenetic deregulation of GATA3 in neuroblastoma is associated with increased GATA3 protein expression and with poor outcomes
  2. 8362
    “…The toxicitic mechanism involves excess ROS generation. 14-3-3s have the protective effects on various injured tissues and cells. …”
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    Tetramethylpyrazine Attenuates the Endotheliotoxicity and the Mitochondrial Dysfunction by Doxorubicin via 14-3-3γ/Bcl-2
  3. 8363
    “…Five variants showed differences in CYP3A catalytic activity: three CYP3A28 SNVs reduced TST 6β-hydroxylation; one CYP3A38 variant increased TST 16β-hydroxylation, while a CYP3A48 SNV showed enhanced NIF oxidation. …”
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    Functional impact of cytochrome P450 3A (CYP3A) missense variants in cattle
  4. 8364
    “…Whole blood cell RNASeq analysis was undertaken in a separate cohort of n = 31 SLE patients, and n = 28 healthy donors. RESULTS: Serum IL‐3 levels correlated with IFNα (r = 0.612, 95% CI 0.455–0.733, P < 0.001) and type III IFN (r = 0.585, 95% CI 0.406–0.720, P < 0.0001). …”
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    A potential association between IL‐3 and type I and III interferons in systemic lupus erythematosus
  5. 8365
    “…Thus, this study aims to extensively examine the distribution of CCL3L1 copy number in the three major populations from Malaysia namely Malay, Chinese and Indian. …”
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    Copy number variation of CCL3L1 among three major ethnic groups in Malaysia
  6. 8366
    “…Furthermore, NLRP3 was found to be degraded by the overexpression of ZIKV NS3 in 293T cells. …”
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    Zika Virus Impairs Host NLRP3-mediated Inflammasome Activation in an NS3-dependent Manner
  7. 8367
    “…Improving on currently available RNA-seq methods we have developed TM3′seq, a 3′-enriched library preparation protocol that uses Tn5 transposase and preserves sample identity at each step. …”
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    TM3’seq: A Tagmentation-Mediated 3’ Sequencing Approach for Improving Scalability of RNAseq Experiments
  8. 8368
    “…As expected, PTPRM bound to wild-type STAT3 but not the STAT3 Y705F mutant. PTPRM dephosphorylated STAT3 in the absence of DDIAS, suggesting that DDIAS hampers PTPRM/STAT3 interaction. …”
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    DDIAS promotes STAT3 activation by preventing STAT3 recruitment to PTPRM in lung cancer cells
  9. 8369
    “…This review highlights the unique role of Ru(III) complexes in the current panorama of anticancer agents, with particular emphasis on Ru-containing nanoformulations based on the incorporation of the Ru(III) complexes into suitable nanocarriers in order to enhance their bioavailability and pharmacokinetic properties. …”
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    Anticancer Ruthenium(III) Complexes and Ru(III)-Containing Nanoformulations: An Update on the Mechanism of Action and Biological Activity
  10. 8370
    “…The stromal antigen 3 (STAG3) gene, encoding a meiosis-specific cohesin component, is a strong candidate for causing male infertility, but little is known about this gene so far. …”
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    The association of stromal antigen 3 (STAG3) sequence variations with spermatogenic impairment in the male Korean population
  11. 8371
    “…The pathology of spinocerebellar ataxia type 3, also known as Machado‐Joseph disease, is triggered by aggregation of toxic ataxin‐3 (ATXN3) variants containing expanded polyglutamine repeats. …”
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    The Machado–Joseph disease deubiquitylase ataxin‐3 interacts with LC3C/GABARAP and promotes autophagy
  12. 8372
    por Noto, Shinichi, Uemura, Takamoto
    Publicado 2020
    “…BACKGROUND: The McMaster Health Utilities Index Mark 3 (HUI3) is a generic multi-attribute, preference-based system for assessing health-related quality of life (HRQOL). …”
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    Japanese health utilities index mark 3 (HUI3): measurement properties in a community sample
  13. 8373
    “…In this review we will take a holistic, organismal view of ILC3 biology and explore the tissue sensory circuits that regulate ILC3 function and align ILC3 responses with changes within the intestinal environment.…”
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    Immunoregulatory Sensory Circuits in Group 3 Innate Lymphoid Cell (ILC3) Function and Tissue Homeostasis
  14. 8374
    “…BACKGROUND: 14-3-3η is an intracellular protein also detected in the serum and synovial fluid of patients with rheumatoid arthritis (RA). …”
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    Tumour necrosis factor alpha promotes secretion of 14-3-3η by inducing necroptosis in macrophages
  15. 8375
    “…However, the underlying mechanism for the functions of NDRG3 remains unclear. Here, we report the crystal structure of human NDRG3 at 2.2 Å resolution, with six molecules in an asymmetric unit. …”
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    Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein
  16. 8376
    “…We previously demonstrated that the host restriction factor-APOBEC3B (A3B) inhibited HBV replication which was dependent on its deaminase activity during reverse transcription. …”
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    DHX9 interacts with APOBEC3B and attenuates the anti-HBV effect of APOBEC3B
  17. 8377
    “…Spindle and kinetochore associated complex subunit 3 (SKA3) plays a key role in cervical cancer development, but its contribution to LUAD is unknown. …”
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    SKA3 promotes lung adenocarcinoma metastasis through the EGFR–PI3K–Akt axis
  18. 8378
    “…Three and six cases of cut-out were noted in the U-blade Gamma3 and Gamma3 nail groups, respectively (P=0.18), however no other postoperative complications were noted in either group. …”
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    A Comparison of U-blade Gamma3 and Gamma3 Nails Used for the Treatment of Intertrochanteric Fractures
  19. 8379
    “…Vertebrates exhibit specific requirements for replicative H3 and non-replicative H3.3 variants during development. …”
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    Histone variant H3.3 residue S31 is essential for Xenopus gastrulation regardless of the deposition pathway
  20. 8380
    “…In this study, we isolated the level of error in 3D facial images attributable to four sources, using the 3dMDface and Vectra H1 camera systems. …”
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    Sources of variation in the 3dMDface and Vectra H1 3D facial imaging systems
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