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8441por Shi, Yefei, Xu, Xu, Luan, Peipei, Kou, Wenxin, Li, Mingjie, Yu, Qing, Zhuang, Jianhui, Xu, Yawei, Peng, Wenhui, Jian, Weixia“…A dual-luciferase reporter revealed STAT3 as the target of miR-124-3p. The expression levels of miR-124-3p in human blood were negatively correlated with ankle-brachial index, which is an index for the evaluation of the severity of PAD. …”
Publicado 2020
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8442por Pichler, Gregor, Stöggl, Wolfgang, Trippel, Daniela, Candotto Carniel, Fabio, Muggia, Lucia, Ametrano, Claudio Gennaro, Çimen, Tuğçe, Holzinger, Andreas, Tretiach, Mauro, Kranner, Ilse“…Here, we studied cellular and extracellularly released phytohormones in three lichen mycobionts, Cladonia grayi, Xanthoria parietina and Tephromela atra, grown on solid medium, and the effects of indole-3-acetic acid (IAA) on their respective photobionts, Asterochloris glomerata, Trebouxia decolorans, Trebouxia sp. …”
Publicado 2020
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8443UAF1 deubiquitinase complexes facilitate NLRP3 inflammasome activation by promoting NLRP3 expressionpor Song, Hui, Zhao, Chunyuan, Yu, Zhongxia, Li, Qizhao, Yan, Rongzhen, Qin, Ying, Jia, Mutian, Zhao, Wei“…NOD-like receptor protein 3 (NLRP3) detects microbial infections or endogenous danger signals and activates the NLRP3 inflammasome, which has important functions in host defense and contributes to the pathogenesis of inflammatory diseases, and thereby needs to be tightly controlled. …”
Publicado 2020
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8444por Steeds, Hannah G., Knowles, Jonathan P., Yu, Wai L., Richardson, Jeffery, Cooper, Katie G., Booker‐Milburn, Kevin I.“…A three‐step synthesis of the 2‐azabicyclo[3.3.1]nonane ring system from simple pyrroles, employing a combined photochemical/palladium‐catalysed approach is reported. …”
Publicado 2020
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8445“…We found that AKI significantly decreases H3S28ph while increasing H3K27me3 specifically in H3K27M tumors. …”
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8446“…The phosphoinositide 3-kinase (PI3K)/AKT signalling pathway is hyperactivated in ~70% of breast cancers. …”
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8447“…An 11‐year‐old Thoroughbred gelding with a history of poor performance was diagnosed with an atrial septal defect, measuring approximately 2 cm in diameter, on 2D transthoracic echocardiography. Real‐time three‐dimensional (3D) echocardiography was used to map the structure of the defect and was useful in fully characterising the ASD in this case.…”
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8448
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8449por Torbøl Pedersen, Jesper, De Loma, Jessica, Levi, Michael, Palmgren, Michael, Broberg, Karin“…In humans and other eukaryotic organisms, the arsenite methyltransferase (AS3MT) protein methylates arsenite. AS3MT sequences from eukaryotic organisms group phylogenetically with predicted eubacterial AS3MT sequences, which has led to the suggestion that AS3MT was acquired from eubacteria by multiple events of horizontal gene transfer. …”
Publicado 2020
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8450por Paruch, Kinga, Popiołek, Łukasz, Biernasiuk, Anna, Hordyjewska, Anna, Malm, Anna, Wujec, Monika“…The aim of our study was the two-stage synthesis of 1,3,4-oxadiazole derivatives. The first step was the synthesis of hydrazide–hydrazones from 3-methyl-4-nitrobenzhydrazide and the corresponding substituted aromatic aldehydes. …”
Publicado 2020
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8451“…However, the effects of liraglutide on osteoblast proliferation and differentiation in MC3T3-E1 cells have not been fully elucidated. In the present study, the promoting effects of liraglutide were investigated in MC3T3-E1 cells. …”
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8452por Montera, Marena, Goins, Aleyah, Cmarko, Leos, Weiss, Norbert, Westlund, Karin N., Alles, Sascha R. A.“…In this brief report, we demonstrate that the Ca(v)3.3 T-type voltage-gated calcium channel subtype is involved in our FRICT-ION model of chronic trigeminal neuropathic pain. …”
Publicado 2020
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8453por Xin, Yongan, Jin, Yifei, Ge, Juan, Huang, Zhenyue, Han, Longsen, Li, Congyang, Wang, Danni, Zhu, Shuai, Wang, Qiang“…In the present study, we focused on whether SIRT3‐GSK3β pathway mediates the meiotic defects in oocytes from diabetic mice. …”
Publicado 2020
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8454
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8455B3GNT3: A prognostic biomarker associated with immune cell infiltration in pancreatic adenocarcinomapor Kong, Kaiwen, Zhao, Yuanyu, Xia, Leilei, Jiang, Hui, Xu, Mingjuan, Zheng, Jianming“…Therefore, there is a need to identify effective biomarkers, such as UDP-GlcNAc: βGal β-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3), that predict the survival outcome of patients with pancreatic cancer. …”
Publicado 2021
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8456por Meereboer, Kjeld W., Pal, Akhilesh K., Cisneros-López, Erick O., Misra, Manjusri, Mohanty, Amar K.“…Worldwide, improper disposal of plastics is instigating environmental initiatives to combat plastics accumulation of in the environment and the world’s oceans. Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) biocomposites with Miscanthus (Misc) fibres and distillers’ dried grains with solubles (DDGS) were studied to ascertain if natural fibres and proteinaceous fillers can improve polyhydroxyalkanoate marine biodegradability. …”
Publicado 2021
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8457por Li, Jun-Lin, Wang, Xiao-Hui, Sun, Jun-Chao, Peng, Yi-Yuan, Ji, Cong-Bin, Zeng, Xing-Ping“…Herein, a chiral tertiary amine catalyzed [4 + 2] cyclization of 3-aroylcoumarines with benzyl 2,3-butadienoate was reported. …”
Publicado 2021
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8458por Moreno-Alcázar, Ana, Ramos-Quiroga, Josep A., Ribases, Marta, Sánchez-Mora, Cristina, Palomar, Gloria, Bosch, Rosa, Salavert, Josep, Fortea, Lydia, Monté-Rubio, Gemma C., Canales-Rodríguez, Erick J., Milham, Michael P., Castellanos, F. Xavier, Casas, Miquel, Pomarol-Clotet, Edith, Radua, Joaquim“…We recruited and genotyped adult patients with combined type ADHD and healthy controls to achieve a sample balanced for age, sex, premorbid IQ, and three ADGRL3 haplotype groups (risk, protective, and others). …”
Publicado 2021
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8459por Avagliano Trezza, Rossella, Punt, A. Mattijs, Mientjes, Edwin, van den Berg, Marlene, Zampeta, F. Isabella, de Graaf, Ilona J., van der Weegen, Yana, Demmers, Jeroen A. A., Elgersma, Ype, Distel, Ben“…Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by brain-specific loss of UBE3A, an E3 ubiquitin protein ligase. A substantial number of possible ubiquitination targets of UBE3A have been identified, although evidence of being direct UBE3A substrates is often lacking. …”
Publicado 2021
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8460por Tugaeva, Kristina V., Hawkins, Dorothy E.D.P., Smith, Jake L.R., Bayfield, Oliver W., Ker, De-Sheng, Sysoev, Andrey A., Klychnikov, Oleg I., Antson, Alfred A., Sluchanko, Nikolai N.“…Binding of phosphorylated SARS-CoV N to the host 14-3-3 protein in the cytoplasm was reported to regulate nucleocytoplasmic N shuttling. …”
Publicado 2021
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