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  1. 8481
    por Zhang, Yanjun, Fang, Dong
    Publicado 2021
    “…The histone H3.3K36M mutation, identified in over 90% of chondroblastoma cases, reprograms the H3K36 methylation landscape and gene expression to promote tumorigenesis. …”
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  2. 8482
    por Takei, Yuma, Ishida, Takashi
    Publicado 2021
    “…Model quality assessment (MQA), which selects near-native structures from structure models, is an important process in protein tertiary structure prediction. The three-dimensional convolution neural network (3DCNN) was applied to the task, but the performance was comparable to existing methods because it used only atom-type features as the input. …”
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  3. 8483
    “…Previous studies on accuracy of three-dimensional (3D) printed model focused on full arch measurements at few points. …”
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  4. 8484
    “…[Image: see text] A novel asymmetric phase-transfer-catalyzed γ-alkylation of phthalide 3-carboxylic esters has been developed, giving access to 3,3-disubstituted phthalide derivatives, which present a chiral quaternary γ-carbon in good to excellent yields and good enantioselectivities (74–88% ee). …”
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  5. 8485
  6. 8486
    “…This compound crystallized in the space group P [Image: see text] and the structure features three η (5)-coordinated Cp′ rings and a κ (3)-coordinated (BH(4))(−) ligand.…”
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  7. 8487
    “…The present works focus on the synthesis of a novel three-dimensional (3D) polymer-metal–carbon (3D-PMC) framework for the exclusion of contaminants (chemical and biological) from water bodies. …”
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  8. 8488
    “…To overcome the problem of low vortex penetration field in Nb(3)Sn, it has been proposed to coat Nb cavities with thin film Nb(3)Sn multilayers with dielectric interlayers. …”
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  9. 8489
    “…KMT2D and NOTCH1 previously have been reported to be associated with CHDs, however, WDFY3 is reported for the first time to be possibly related to CHD in human. …”
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  10. 8490
    “…A simple and efficient BF(3)-OEt(2) promoted C3-alkylation of indole has been developed to obtain3-indolylsuccinimidesfrom commercially available indoles and maleimides, with excellent yields under mild reaction conditions. …”
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  11. 8491
    “…The aim of this study was to investigate the expression of phosphatase of regenerating live-3 (PRL-3) in human stage III colorectal cancer (CRC) and to evaluate its correlation with metachronous liver metastasis (MLM) and prognosis. …”
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  12. 8492
    “…Here, we demonstrate that the adaptor molecule Bat3 acts as a molecular checkpoint of T cell exhaustion, with deficiency of Bat3 promoting a profound exhaustion phenotype, suppressing autoreactive T cell–mediated neuroinflammation. …”
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  13. 8493
    “…More recently, newer technologies such as three-dimensional (3D) scanning and 3D printing have been applied in breast assessment. …”
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  14. 8494
  15. 8495
    “…Golgi phosphoprotein 3 (GOLPH3) has been demonstrated to promote tumor progression in various gastrointestinal malignancies. …”
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  16. 8496
  17. 8497
    “…MDM2 proto-oncogene, E3 ubiquitin protein ligase (MDM2) is a well-known oncogene and has been reported to be closely associated with epithelial-to-mesenchymal transition (EMT). …”
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  18. 8498
  19. 8499
    “…BACKGROUND: We compared the outcomes of three fixation techniques for Müller type C2 and C3 distal femoral fractures. …”
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  20. 8500
    “…Regioselective 1,1′,3,3′-tetrazincation [C–H to C–Zn(tBu)] of ferrocene has been achieved by reaction of a fourfold excess of di-t-butylzinc (tBu(2)Zn) with sodium 2,2,6,6-tetramethylpiperidide (NaTMP) in hexane solution manifested in the trimetallic iron–sodium–zinc complex [Na(4)(TMP)(4)Zn(4)(tBu)(4){(C(5)H(3))(2)Fe}], 1. …”
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