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9921por Spahiu, Lidvana, Behluli, Emir, Peterlin, Borut, Nefic, Hilada, Hadziselimovic, Rifat, Liehr, Thomas, Temaj, Gazmend“…Here we provide an overview on known molecular basis of MPS in general, including enzyme defects and symptoms of MPS; however, the main focus is on MPS type III together with potential and perspective therapy-options.…”
Publicado 2021
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9922“…Central nervous system expression of MT isoform 3 (MT3) is thought to be neuroprotective. We report for the first time on the metalation pathways of As(3+) binding to apo-MT3 under physiological conditions, yielding the absolute binding constants (log K(n), n = 1–6) for each sequential As(3+) binding event: 10.20, 10.02, 9.79, 9.48, 9.06, and 8.31 M(−1). …”
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9923por Chen, Phang-Lang“…SUV3 is a nuclear-encoded helicase that is highly conserved and localizes to the mitochondrial matrix. …”
Publicado 2023
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9925
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9926por Ma, Meng, Gu, Jun, Wang, Dong-An, Bi, Siwei, Liu, Ruiqi, Zhang, Xiaosheng, Yang, Jing, Zhang, Yi“…In this paper, we first briefly introduce various 3D printing technologies commonly used in the biomedical field, particularly in aging research and aging care. …”
Publicado 2023
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9927por Wang, Meng, Sreenivas, Prethish, Sunkel, Benjamin D, Wang, Long, Ignatius, Myron, Stanton, Benjamin Z“…We report a comprehensive 3D chromatin structural analysis and characterization of fusion-positive (FP-RMS) and fusion-negative RMS (FN-RMS). …”
Publicado 2023
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9928“…The limitations in 2D monolayer cell culture have a substantial role in the existing limitations of understanding cell-to-cell interactions in the pulpal and periapical tissues. Three-dimensional (3D) tissue constructs with two or more different cell populations are a better physiological representation of in vivo environment. …”
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9929“…In this review, we consider various aspects of enhancer functioning in the context of the 3D genome. Particular attention is paid to the mechanisms of enhancer-promoter communication and the significance of the spatial juxtaposition of enhancers and promoters in 3D nuclear space. …”
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9931“…Despite decades of investigations, the underlying mechanism of CED-4–facilitated CED-3 activation remains elusive. Here, we report cryo-EM structures of the CED-4 apoptosome and three distinct CED-4/CED-3 complexes that mimic different activation stages for CED-3. …”
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9932“…Serine/arginine rich splicing factor 3 (SRSF3) is an important multi-functional splicing factor, and has attracted increasing attentions in the past thirty years. …”
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9933por Liu, Hao, Tsai, Hsiangyu, Yang, Maoquan, Li, Guozhi, Bian, Qian, Ding, Gang, Wu, Dandan, Dai, Jiewen“…Linear DNA undergoes a series of compression and folding events, forming various three‐dimensional (3D) structural units in mammalian cells, including chromosomal territory, compartment, topologically associating domain, and chromatin loop. …”
Publicado 2023
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9934“…Patients presenting with 3rd-degree AVB with ventricular escape rhythms can destabilize. …”
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9935por Azizi, Ghobad, Mayo, Michelle L., Ogden, Lorna L., Farrell, Jessica, Piper, Kele, Malchoff, Carl“…Thyroid 2D US showed an isoechoic solid TN with regular margins measuring 12 × 8 × 10 mm (TR3) in the left thyroid lobe. 3D US demonstrated markedly irregular margins. …”
Publicado 2023
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9936“…Neurexin-3 is primarily localized in the presynaptic membrane and forms complexes with various ligands located in the postsynaptic membrane. …”
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9937por Martinez-Lopez, Sebastian, Angel-Gomis, Enrique, Sanchez-Ardid, Elisabet, Pastor-Campos, Alberto, Picó, Joanna, Gomez-Hurtado, Isabel“…SIMPLE SUMMARY: This article provides a review of recent studies that explore the application of the 3Rs in experimental animal models of liver disease, comparing different models for a correct search for replacement, refinement, and reduction methods. …”
Publicado 2023
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9939por Sowmya, Meleti Venkata, Mehrotra, Divya, Mohammad, Shadab, Singh, R.K., Tiwari, Arunesh Kumar, Katrolia, Ravi, Sharma Yogesh, Shivani“…MATERIAL AND METHODS: A cross-sectional study was conducted in our institutional OPD in a tertiary health care centre in the Northern part of India.400 people were chosen based on selection criteria. facial scans were done for 3D pictures using Canfield VECTRA® H2 3D imaging device. …”
Publicado 2023
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9940por Kleinbongard, Petra“…Activation of signal transducer and activator of transcription 3 (STAT3) has been identified as a key cardioprotective signal not only in animal studies but also in humans—in animals, STAT3 is causally involved in cardioprotection. …”
Publicado 2023
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