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  1. 9921
    “…Here we provide an overview on known molecular basis of MPS in general, including enzyme defects and symptoms of MPS; however, the main focus is on MPS type III together with potential and perspective therapy-options.…”
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  2. 9922
    por Yuan, Amelia T., Stillman, Martin J.
    Publicado 2023
    “…Central nervous system expression of MT isoform 3 (MT3) is thought to be neuroprotective. We report for the first time on the metalation pathways of As(3+) binding to apo-MT3 under physiological conditions, yielding the absolute binding constants (log K(n), n = 1–6) for each sequential As(3+) binding event: 10.20, 10.02, 9.79, 9.48, 9.06, and 8.31 M(−1). …”
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  3. 9923
    por Chen, Phang-Lang
    Publicado 2023
    “…SUV3 is a nuclear-encoded helicase that is highly conserved and localizes to the mitochondrial matrix. …”
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  4. 9924
  5. 9925
  6. 9926
    “…In this paper, we first briefly introduce various 3D printing technologies commonly used in the biomedical field, particularly in aging research and aging care. …”
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  7. 9927
    “…We report a comprehensive 3D chromatin structural analysis and characterization of fusion-positive (FP-RMS) and fusion-negative RMS (FN-RMS). …”
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  8. 9928
    por Li, Fang-Chi, Kishen, Anil
    Publicado 2023
    “…The limitations in 2D monolayer cell culture have a substantial role in the existing limitations of understanding cell-to-cell interactions in the pulpal and periapical tissues. Three-dimensional (3D) tissue constructs with two or more different cell populations are a better physiological representation of in vivo environment. …”
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  9. 9929
    “…In this review, we consider various aspects of enhancer functioning in the context of the 3D genome. Particular attention is paid to the mechanisms of enhancer-promoter communication and the significance of the spatial juxtaposition of enhancers and promoters in 3D nuclear space. …”
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  10. 9930
  11. 9931
    por Li, Yini, Tian, Lu, Zhang, Ying, Shi, Yigong
    Publicado 2023
    “…Despite decades of investigations, the underlying mechanism of CED-4–facilitated CED-3 activation remains elusive. Here, we report cryo-EM structures of the CED-4 apoptosome and three distinct CED-4/CED-3 complexes that mimic different activation stages for CED-3. …”
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  12. 9932
    por Jia, Rong, Zheng, Zhi-Ming
    Publicado 2023
    “…Serine/arginine rich splicing factor 3 (SRSF3) is an important multi-functional splicing factor, and has attracted increasing attentions in the past thirty years. …”
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  13. 9933
    “…Linear DNA undergoes a series of compression and folding events, forming various three‐dimensional (3D) structural units in mammalian cells, including chromosomal territory, compartment, topologically associating domain, and chromatin loop. …”
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  14. 9934
    por Meloy, Patrick, Rutz, Dan, Bhambri, Amit
    Publicado 2022
    “…Patients presenting with 3rd-degree AVB with ventricular escape rhythms can destabilize. …”
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  15. 9935
    “…Thyroid 2D US showed an isoechoic solid TN with regular margins measuring 12 × 8 × 10 mm (TR3) in the left thyroid lobe. 3D US demonstrated markedly irregular margins. …”
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  16. 9936
    “…Neurexin-3 is primarily localized in the presynaptic membrane and forms complexes with various ligands located in the postsynaptic membrane. …”
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  17. 9937
    “…SIMPLE SUMMARY: This article provides a review of recent studies that explore the application of the 3Rs in experimental animal models of liver disease, comparing different models for a correct search for replacement, refinement, and reduction methods. …”
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  18. 9938
  19. 9939
    “…MATERIAL AND METHODS: A cross-sectional study was conducted in our institutional OPD in a tertiary health care centre in the Northern part of India.400 people were chosen based on selection criteria. facial scans were done for 3D pictures using Canfield VECTRA® H2 3D imaging device. …”
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  20. 9940
    por Kleinbongard, Petra
    Publicado 2023
    “…Activation of signal transducer and activator of transcription 3 (STAT3) has been identified as a key cardioprotective signal not only in animal studies but also in humans—in animals, STAT3 is causally involved in cardioprotection. …”
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