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1021“…Lymphocyte activation gene-3 (LAG-3), T cell immunoglobulin and mucin-domain-containing-3 (TIM-3), and T cell immunoreceptor with immunoglobulin and tyrosine-based inhibitory motif (ITIM) domain (TIGIT) constitute the second wave of immunotherapy targets that show great promise for use in the treatment of solid tumors and leukemia. …”
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1022“…This study resampled and analyzed putative paleosols within and below the Strelley Pool Formation (3.3 Ga), at four classic locations: Strelley Pool, Steer Ridge, Trendall Ridge, and Streckfuss, and also at newly discovered outcrops near Marble Bar. …”
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1023“…This review consolidates over three decades of research about the role of TPM3 in skeletal muscle. …”
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1024“…METHODS: An established and psychometrically valid questionnaire was administered to 524 nurses, covering three grades and coming from five provinces. RESULTS: Significant differences in job profile were found in nurses from different provinces, suggesting that the nature of the role is determined to some degree by the geographical location of practice. …”
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1025“…A [3 + 3] annelation of enantiomerically pure aziridine 7 provides the functionalised piperidine 8 that can be elaborated to the indolizidine skeleton in only 4 steps with good stereocontrol.…”
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1026por Untergasser, Andreas, Nijveen, Harm, Rao, Xiangyu, Bisseling, Ton, Geurts, René, Leunissen, Jack A.M.“…Here we present Primer3Plus, a new web interface to the popular Primer3 primer design program as an enhanced alternative for the CGI- scripts that come with Primer3. …”
Publicado 2007
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1027“…In contrast, excess CD displaces up to 40% of the bound [3H]CB. These results suggest that three different classes of high-affinity CB binding sites exist in 3T3 cells: sites related to sugar transport, sites related to cell motility and morphology, and sites with undetermined function.…”
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1028Publicado 1979“…This paper reports that the angular distribution of directional change of 3T3 cells which followed guiding lines on a substrate and left the guidance at various angles shows a peculiar preference for angles between 30 degrees and 60 degrees. …”
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1029Publicado 1980“…In differentiating 3T3-L1 cells, lipid spheres, the endoplasmic reticulum (ER), microperoxisomes, and mitochondria form "constellations" that may reflect the interplay of lipid metabolizing enzymes in these organelles. …”
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1030Publicado 1977“…Using a new technique to visualize the tracks of moving 3T3 cells and combining it with the visualization of actin-containing microfilament bundles by indirect immunofluorescence (Lazarides, E. and K. …”
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1032por Mueller-Dieckmann, Christoph, Kernstock, Stefan, Mueller-Dieckmann, Jochen, Weiss, Manfred S., Koch-Nolte, Friedrich“…The three-dimensional structure has been resolved at a resolution of 1.8 Å. …”
Publicado 2008
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1033“…Tumour and normal tissue from 41 male cases of Wilms' tumour were screened to determine the presence of sequence variants in the glypican 3 (GPC3) gene. Two non-conservative single base changes were present in tumour tissue only. …”
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1034por Pavlopoulos, Georgios A, O'Donoghue, Seán I, Satagopam, Venkata P, Soldatos, Theodoros G, Pafilis, Evangelos, Schneider, Reinhard“…RESULTS: We present a new visualization tool, Arena3D, which introduces a new concept of staggered layers in 3D space. …”
Publicado 2008
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1037por Johnson, Catherine, Crowther, Sandra, Stafford, Margaret J., Campbell, David G., Toth, Rachel, MacKintosh, Carol“…More than 200 phosphorylated 14-3-3-binding sites in the literature were analysed to define 14-3-3 specificities, identify relevant protein kinases, and give insights into how cellular 14-3-3/phosphoprotein networks work. …”
Publicado 2010
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1038
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