“…Phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that regulate diverse cellular processes including proliferation, adhesion, survival, and motility. …”
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“…OBJECTIVES: The aim of this study is to investigate the correlation between 2-dimensional (2D) cephalometric measurement and 3-dimensional (3D) cone beam computed tomography (CBCT) measurement, and to evaluate the availability of 3D analysis for asymmetry patients. …”
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“…RNA polymerase III (Pol III) occurs in two versions, one containing the POLR3G subunit and the other the closely related POLR3GL subunit. …”
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“…Its structure is isotypic to that of the lead analogue PbMn(II) (2)Mn(III)(PO(4))(3). Two O atoms are in general positions, whereas all others atoms are in special positions. …”
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“…Its structure is isotypic with the lead and strontium analogues AMn(II) (2)Mn(III)(PO(4))(3) (A = Pb, Sr). Except for two O atoms on general positions, all atoms are located on special positions. …”
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“…In the crystal, the cations and anions are linked by classical N—H⋯Cl hydrogen bond and weak C—H⋯Cl and C—H⋯O hydrogen bonds; the C—H⋯O hydrogen bonds exhibit R (2) (2)(14) ring motifs while the C—H⋯Cl hydrogen bonds link the mol­ecules into chains along the a-axis direction. π–π stacking is observed between parallel phenyl rings of adjacent cations, the centroid–centroid distance being 3.8164 (15) Å.…”
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“…Aberrant expression of oncogenic 14-3-3 proteins is correlated with poor survival of cancer patients. …”
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“…The present study explored the factors responsible for the differentiation of 3T3-L1 white preadipocytes to beige adipocytes. …”
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“…The title compound, C(6)H(4)IN(3), is essentially planar, with a dihedral angle of 0.82 (3)° between the planes of the pyridine and pyrazole rings. …”
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“…In addtion, weak C—H⋯π inter­actions and π–π stacking inter­actions between benzene and pyrimidine rings, with a centroid–centroid distance of 3.730 (3) Å, link the chains, forming a two-dimensional network parallel to (001).…”
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“…In addition, we compare expression profiles and alternative splicing patterns for CenH3 in representatives of each genus. RESULTS: All three genera retain both duplicated CenH3 copies, while Brassica and Gossypium exhibit pronounced homoeologous expression level bias. …”
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“…The phosphorylation in cells is regulated by growth factors and is sensitive to phosphatidyl inositol-3 kinase (PI3K) inhibitors. This phosphorylation generates binding sites to the 14-3-3 regulatory proteins, which are involved in the regulation of nucleocytoplasmic shuttling of target proteins, restricting phosphorylated Notch4-ICD to the cytoplasm. …”
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“…The effect of hydrogen sulfide (H(2)S) on differentiation of 3T3L1-derived adipocytes was examined. Endogenous H(2)S was increased after 3T3L1 differentiation. …”
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“…The H3.3 histone variant has been a subject of increasing interest in the field of chromatin studies due to its two distinguishing features. …”
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“…Our structural and biochemical studies reveal an unusually tight interaction between ULK3 and IST1, an ESCRT-III subunit required for abscission. …”
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“…Congenital hepatic fibrosis is a relatively rare disease of children and young adults characterized by hard hepatomegaly, portal hypertension with relative preservation of liver function and underlying architecture, and frequent renal involvement. We experienced 3 cases of congenital hepatic fibrosis with Caroli’s disease in 3 siblings, whose clinical manifestations were diverse, such as repeated cholangitis, variceal hemorrhage, or intrahepatic stones. …”
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“…Flavihumibacter solisilvae 3-3(T) (= KACC 17917(T) = JCM 19891(T)) represents a type strain of the genus Flavihumibacter within the family Chitinophagaceae. …”
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“…BACKGROUND: The family of 14-3-3 proteins plays an important role in the regulation of cell survival and death. …”
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